Comparison of the Pain-relieving Effects of Human Milk, Sucrose, and Distilled Water during Examinations for Retinopathy of Prematurity: A Randomized Controlled Trial |
Jang, Eun Kyung
(Department of Neonatology, Neonatal Intensive Care Unit, Severance Hospital)
Lee, Hyejung (College of Nursing.Mo-Im Kim Nursing Research Institute, Yonsei University) Jo, Keum Sik (Department of Neonatology, Neonatal Intensive Care Unit, Severance Hospital) Lee, Sung Mi (Department of Neonatology, Neonatal Intensive Care Unit, Severance Hospital) Seo, Hyun Jin (Department of Neonatology, Neonatal Intensive Care Unit, Severance Hospital) Huh, Eun Joo (Department of Neonatology, Neonatal Intensive Care Unit, Severance Hospital) |
1 | Sun X, Lemyre B, Barrowman N, O'Connor M. Pain management during eye examinations for retinopathy of prematurity in preterm infants: A systematic review. Acta Paediatrica. 2010;99(3):329-334. https://doi.org/10.1111/j.1651-2227.2009.01612.x DOI |
2 | Mokhnach L, Anderson M, Glorioso R, Loeffler K, Shinabarger K, Thorngate L, et al. NICU procedures are getting sweeter: Development of a sucrose protocol for neonatal procedural pain. Neonatal Network. https://doi.org/10.1891/0730-0832.29.5.271 |
3 | Disher T, Cameron C, Mitra S, Cathcart K, Campbell-Yeo M. Painrelieving interventions for retinopathy of prematurity: A metaanalysis. Pediatrics. 2018;142(1):e20180401. https://doi.org/10.1542/peds.2018-0401 DOI |
4 | Mangat AK, Oei JL, Chen K, Quah-Smith I, Schmolzer GM. A review of non-pharmacological treatments for pain management in newborn infants. Children. 2018;5(10):E130. https://doi.org/10.3390/children5100130 DOI |
5 | Stevens B, Yamada J, Campbell-Yeo M, Gibbins S, Harrison D, Dionne K, et al. The minimally effective dose of sucrose for procedural pain relief in neonates: A randomized controlled trial. BMC Pediatrics. 2018;18(1):85. https://doi.org/10.1186/s12887-018-1026-x DOI |
6 | Kristoffersen L, Malahleha M, Duze Z, Tegnander E, Kapongo N, Stoen R, et al. Randomised controlled trial showed that neonates received better pain relief from a higher dose of sucrose during venepuncture. Acta Paediatrica. 2018;107(12):2071-2078. https://doi.org/10.1111/apa.14567 DOI |
7 | Gao H, Gao H, Xu G, Li M, Du S, Li F, et al. Efficacy and safety of repeated oral sucrose for repeated procedural pain in neonates: A systematic review. International Journal of Nursing Studies. 2016;62:118-125. https://doi.org/10.1016/j.ijnurstu.2016.07.015 DOI |
8 | Ribeiro LM, Castral TC, Montanholi LL, Dare MF, Silva AC, Antonini SR, et al. Human milk for neonatal pain relief during ophthalmoscopy. Revista da Escola de Enfermagem da USP. 2013;47(5):1039-1045. https://doi.org/10.1590/s0080-623420130000500005 DOI |
9 | Dolgun G, Bozlak S. Effect of nonpharmacologic pain control during examination for retinopathy of prematurity. Journal of Obstetric, Gynecologic, and Neonatal Nursing. 2017;46(5):709-715. https://doi.org/10.1016/j.jogn.2017.06.008 DOI |
10 | Rosali L, Nesargi S, Mathew S, Vasu U, Rao SP, Bhat S. Efficacy of expressed breast milk in reducing pain during ROP screening--A randomized controlled trial. Journal of Tropical Pediatrics. 2015; 61(2):135-138. https://doi.org/10.1093/tropej/fmu073 DOI |
11 | Desai S, Nanavati RN, Nathani R, Kabra N. Effect of expressed breast milk versus swaddling versus oral sucrose administration on pain associated with suctioning in preterm neonates on assisted ventilation: A randomized controlled trial. Indian Journal of Palliative Care. 2017;23(4):372-378. https://doi.org/10.4103/ijpc.Ijpc_84_17 DOI |
12 | Collados-Gomez L, Ferrera-Camacho P, Fernandez-Serrano E, Camacho-Vicente V, Flores-Herrero C, Garcia-Pozo AM, et al. Randomised crossover trial showed that using breast milk or sucrose provided the same analgesic effect in preterm infants of at least 28 weeks. Acta Paediatrica. 2018;107(3):436-441. https://doi.org/10.1111/apa.14151 DOI |
13 | Sener Taplak A, Erdem E. A comparison of breast milk and sucrose in reducing neonatal pain during eye exam for retinopathy of prematurity. Breastfeeding Medicine. 2017;12(5):305-310. https://doi.org/10.1089/bfm.2016.0122 DOI |
14 | Mitchell A, Green A, Jeffs D, Roberson P. Physiologic effects of retinopathy of prematurity screening examinations. Advances in Neonatal Care. 2011;11(4):291-297. https://doi.org/10.1097/ANC.0b013e318225a332 DOI |
15 | Francis K. What is best practice for providing pain relief during retinopathy of prematurity eye examinations? Advances in Neonatal Care. 2016;16(3):220-228. https://doi.org/10.1097/anc.0000000000000267 DOI |
16 | Stevens B, Johnston C, Petryshen P, Taddio A. Premature infant pain profile: Development and initial validation. The Clinical Journal of Pain. 1996;12(1):13-22. DOI |
17 | Dilli D, Ilarslan NE, Kabatas EU, Zenciroglu A, Simsek Y, Okumus N. Oral sucrose and non-nutritive sucking goes some way to reducing pain during retinopathy of prematurity eye examinations. Acta Paediatrica. 2014;103(2):e76-79. https://doi.org/10.1111/apa.12454 DOI |
18 | O'Sullivan A, O'Connor M, Brosnahan D, McCreery K, Dempsey EM. Sweeten, soother and swaddle for retinopathy of prematurity screening: A randomised placebo controlled trial. Archives of Disease in Childhood Fetal and Neonatal Edition. 2010;95(6):F419-422. https://doi.org/10.1136/adc.2009.180943 DOI |
19 | Ou-Yang MC, Chen IL, Chen CC, Chung MY, Chen FS, Huang HC. Expressed breast milk for procedural pain in preterm neonates: A randomized, double-blind, placebo-controlled trial. Acta Paediatrica. 2013;102(1):15-21. https://doi.org/10.1111/apa.12045 DOI |
20 | Williams AL, Khattak AZ, Garza CN, Lasky RE. The behavioral pain response to heelstick in preterm neonates studied longitudinally: Description, development, determinants, and components. Early Human Development. 2009;85(6):369-374. https://doi.org/10.1016/j.earlhumdev.2009.01.001 DOI |
21 | Gao H, Li M, Gao H, Xu G, Li F, Zhou J, et al. Effect of non-nutritive sucking and sucrose alone and in combination for repeated procedural pain in preterm infants: A randomized controlled trial. International Journal of Nursing Studies. 2018;83:25-33. https://doi.org/10.1016/j.ijnurstu.2018.04.006 DOI |
22 | Lim Y, Godambe S. Prevention and management of procedural pain in the neonate: An update, American Academy of Pediatrics, 2016. Archives of Disease in Childhood Education and Practice Edition. 2017;102(5):254-256. https://doi.org/10.1136/archdischild-2016-311066 DOI |
23 | Committee on Fetus and Newborn and Section on Anesthesiology and Pain Medicine. Prevention and management of procedural pain in the neonate: An update. Pediatrics. 2016;137(2):e20154271. https://doi.org/10.1542/peds.2015-4271 DOI |
24 | Bashinsky AL. Retinopathy of prematurity. North Carolina Medical Journal. 2017;78(2):124-128. https://doi.org/10.18043/ncm.78.2.124 DOI |
25 | Boyle EM, Freer Y, Khan-Orakzai Z, Watkinson M, Wright E, Ainsworth JR, et al. Sucrose and non-nutritive sucking for the relief of pain in screening for retinopathy of prematurity: A randomised controlled trial. Archives of Disease in Childhood Fetal and Neonatal Edition. 2006;91(3):F166-168. https://doi.org/10.1136/adc.2005.087668 |
![]() |