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http://dx.doi.org/10.7584/ktappi.2013.45.1.027

Quantitative analysis of 5-HMF produced from fructose  

Sim, Jaehoon (Department of Wood and Paper Science, College of Agriculture and Life Science, Chungbuk Natl. Univ.)
Shin, Soo-Jeong (Department of Wood and Paper Science, College of Agriculture and Life Science, Chungbuk Natl. Univ.)
Publication Information
Journal of Korea Technical Association of The Pulp and Paper Industry / v.45, no.1, 2013 , pp. 27-34 More about this Journal
Abstract
Quantitative analysis of 5-hydroxymethylfufural (5-HMF) conversion from fructose by dehydration and rearrangement was investigated by $^1H$-NMR spectroscopic method. Fructose was converted to 5-HMF in dimethylsulfoxide (DMSO)-$d^6$ or acidic deuterium hydroxide at controlled reaction temperature and time. With addition of internal standards (biphenyl for DMSO-$d^6$ solvent, and 2,5-dihydroxybenzoic acid for deuterium oxide solvent), conversion from fructose to 5-HMF was analyzed by $^1H$-NMR spectroscopy. Quantitative analysis was run by comparison with peak area integration between of 5-HMF and internal standard. In DMSO solvent, 5-HMF was stable end product but part of 5-HMF was converted to formic and levulinic acid at acidic aqueous medium.
Keywords
fructose; 5-hydroxymethylfurfural (5-HMF); $^1H$-NMR;
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Times Cited By KSCI : 5  (Citation Analysis)
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