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Histopathological Features of Lymphoma in Yogyakarta, Indonesia  

Dwianingsih, Ery Kus (Department of Anatomic Pathology, Universitas Gadjah Mada)
Indrawati, Indrawati (Department of Anatomic Pathology, Universitas Gadjah Mada)
Hardianti, Mardiah Suci (Department of Internal Medicine, Universitas Gadjah Mada)
Malueka, Rusdy Ghazali (Department of Neurology, Universitas Gadjah Mada)
Iswar, Riezka Rivani (Faculty of Medicine, Universitas Gadjah Mada)
Sutapa, Stefani APPG (Faculty of Medicine, Universitas Gadjah Mada)
Triningsih, FX Ediati (Department of Anatomic Pathology, Universitas Gadjah Mada)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.17, no.9, 2016 , pp. 4213-4216 More about this Journal
Abstract
The incidence and prevalence, the second most common lymphoid malignancy after leukemia, are both increasing. The distribution of lymphoma varies among sexes, age groups, and sites. In Indonesia, information about the incidence of lymphoma and its characteristics are insufficient. Therefore, this study was performed to evaluate the incidence of lymphoma and features based on age group, sex, site, clinical diagnosis, and histopathological type in Indonesia. This study is an observational analytical study with a cross-sectional design aimed to evaluate the histopathological profile of lymphoma in Yogyakarta from 2010-2014. It was based on secondary data from Anatomic Pathology Department's medical records from several hospitals and laboratories. The result showed an increased incidence of lymphoma in Yogyakarta in 2010-2014 (p=0.039). Lymphoma mostly occurred in age range 45-64 years (p=0.004), dominated by male with ratio 1.6:1. DLBCL was found to be the most common histopathological type (44.4%). Sex, age, and clinical diagnosis demonstrated statistically significant correlations with the histopathological type (p<0.001). In conclusion, the incidence of lymphoma has significantly increased from 2010-2014. There are statistically significant correlations between gender, age, and clinical diagnosis with the histopathological type of lymphoma.
Keywords
Lymphoma; Hodgkin's; non-Hodgkin's; incidence; Yogyakarta, Indonesia;
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