PHA-Induced Peripheral Blood Cytogenetics and Molecular Anslysis : a Valid Diagnostic and Follow-up Modality For Acute Primyelocytic Leukemia Patients Treated With ATRA and/or Arsenic Tri-oxide |
Baba, Shahid M
(Department of Immunology and Molecular Medicine, Sher-I-Kashmir Institute of Medical Sciences)
Azad, Niyaz A (Department of Immunology and Molecular Medicine, Sher-I-Kashmir Institute of Medical Sciences) Shah, Zaffar A (Department of Immunology and Molecular Medicine, Sher-I-Kashmir Institute of Medical Sciences) Afroze, Dil (Department of Immunology and Molecular Medicine, Sher-I-Kashmir Institute of Medical Sciences) Pandith, Arshad A (Advanced Centre for Human Genetics, Sher-I-Kashmir Institute of Medical Sciences) Jan, Aleem (Departement of Clinical Hematology, Sher-I-Kashmir Institute of Medical Sciences) Aziz, Sheikh A (Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences) Dar, Fayaz A (Advanced Centre for Human Genetics, Sher-I-Kashmir Institute of Medical Sciences) |
1 | Ghavamzadeh A, Alimoghaddam K, Ghaffari SH, et al (2006). Treatment of acute pro myelocytic leukemia with arsenic trioxide without ATRA and/or chemotherapy. Annals Oncol, 17, 131-4. DOI |
2 | Arnould C, Philippe C, Bourdon V, et al (1999). The signal transducer and activator of trans cription STAT5b gene is a new partner of retinoic acid receptor a in acute promyelocyti clike leukemia. Hum Mol Genet, 8, 1741-9. DOI |
3 | Arshad A. Pandith, Mushtaq A. Siddiqi (2012). Burden of cancers in the valley of Kashmir 5 year epidemiological reveals a different scenario. Tumor Biol, 33, 1629-37. DOI |
4 | Bennett JM, Catovsky D, Daniel MT, et al (1985). Proposed revised criteria for the classifi cation of acute myeloid leukemia: a report of the French-American-British Cooperative Group. Ann Intern Med, 103, 460-2. DOI |
5 | Biondi A, Rambaldi A, Pandofi PP, et al (1992). Molecular monitoring of myl/RAR-a fusion gene in acute promyelocytic leukemia by polymerase chain reaction. Blood, 80, 492-7. |
6 | Borrow J, Goddard AD, Gibbons B, et al (1992). Diagnosis of acute promyelocytic leukae mia by RT-PCR detection of PML-RARA and RAR-PML fusion transcripts. Br J Haematol, 82, 529-40. DOI |
7 | Carbone R, Botrugno OA, Ronzoni S, et al (2006). Recruitment ro the histone methyltransfe rase SUB39H1 and its role in the oncogenic properties of the leukemia-associated PML retinoic acid receptor fusion protein. Mol Cell Biol, 26,1288-96. DOI |
8 | Cassnat B, Zassadowski F, Balitrand N, et al (2000). Quantitation of minimal residual disease in acute promyelocytic leukemia patients with t(15;17) translocation using real-time RT-PCR. Leukemia, 14, 324-8. DOI |
9 | Castaigne S, Chomienne C, Daniel MT, et al (1990). All-trans retinoic acid as a differentia tion therapy for acute promyelocytic leukemia. I. Clinical results. Blood, 76, 1704-9. |
10 | Chen SJ, Zelent A, Tong JH, et al (1993). Rearrangements of the retinoic acid receptor alpha and promyelocytic zinc finger genes resulting form t(11;17)(q23;q21) in a patient with acute promyelocytic leukaemia. J Clin Invest, 91, 2260-7. DOI |
11 | Chen Z, Brand NJ, Chen A, et al(1993). Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-a locus due to a variant t(11; 17) translocation asso-ciated with acute promyelocytic leukaemia. EMBO J, 12, 1161-7. |
12 | Chomienne C, Ballerini P, Balitrand N et al (1990). All-trans retinoic acid in acute promye locytic leukemias. In vitro studies Structure-function relationship. Blood, 76, 1710-7. |
13 | David Grimwade, Andrea Biondi, Marie-Joëlle Mozziconacci, et al (2000). Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the euro-pean working party. groupe français de cytogénétique hematologique, groupe de français d'hematologie cellulaire, UK cancer cytogenetics group and BIOMED 1 Eu-ropean community-concerted action "molecular cytogenetic diagnosis in haematolo-gical malignancies. Blood, 96, 1297-308. |
14 | De Botton S, Chevret S, Sanz M, et al (2000). Additional chromosomal abnormalities in pa-tients with acute promyelocytic leukaemia (APML) do not confer poor prognosis results of APML 93 trial. Br J Haematol, 111, 801-6. |
15 | Di Croce L, Raker VA, Corsaro M, et al(2002). Methyltransferase recruitment and DNA Hypermethylation of target promoters by an oncogenic transcription factor. Science, 295, 1079-82. DOI |
16 | Ghavamzadeh A, Alimoghaddam K, Rostami S, et al (2011). Phase II study of single- agent arsenic trioxide for the front-line therapy of acute promyelocytic leukemia. J Clin Oncol, 29, 2753-7. DOI |
17 | Dilworth FJ, Chambon P (2000). Nuclear receptors coordinate the activities of chromatin re-modeling complexes and coactivators to facilitate initiation of transcription. Oncogene, 20, 3047-54. |
18 | Douer D, Santillana S, Ramezani L, et al (2003). Acute promyelocytic leukaemia in patients originating in Latin America is associated with an increased frequency of the bcr1 sub-type of the PML/RARalpha fusion gene. Br J Haematol, 122, 563-570. DOI |
19 | Gallagher R, Willman CL, Slack JL, et al (1997). Association of PML/RARa fusion mRNA type with pretreatment hematologic characteristics but not treatment outcome in hematologic characteristics but not treatment outcome in acute promyelocytic leukemia: an intergroup molecular study. Blood, 90, 1656-63. |
20 | Glass CK, Rosenfeld MG (2000). The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev, 14, 121-41. |
21 | Grimwade D (1999). The pathogenesis of Acute Promyelocytic Leukemia; Evaluation of the role of molecular diagnosis and monitoring in the management of the disease. Br J Hematol, 106, 591-613. DOI |
22 | Huang M, Ye YC, Chen BR, et al(1988). Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood, 72, 567-72. |
23 | Huang W, Sun GL, Li ZS, et al(1993). Acute promyelocytic leukemia: clinical relevance of two major PML-RARa isoforms and detection of minimal residual disease by isoforms and detection of minimal residual disease by retrotrans-criptase/polymerase chain reaction to predict relapse. Blood, 82, 1264-9. |
24 | Mitelman F (1995). An International System for Humann Cytogenetic Nomenclature. S Karger. |
25 | Iqbal S, Grimwade D, Chase A, et al (2000). Identification of PML/ RARalpha rearrange ments in suspected acute promyelocytic leukemia using fluorescence in situ hybridization of bone marrow smears: a comparison with cytogenetic and RT-PCR in MRC ATRA trial patients. MRC Adult Leukaemia Working Party. Leukemia, 14, 950-3. DOI |
26 | Jensen K, Shiels C, Freement PS (2001). PML protein isoforms and the RBCC/TRIM motif. Oncogene, 20, 7223-33. DOI |
27 | Miller WH Jr, Kakizuka A, Frankel SR, et al (1992). Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor-a clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia. Proc Natl Acad Sci USA, 89, 2694-8. DOI |
28 | Niyaz A Azad, Shahid M Baba, Zafar A Shah, et al (2015). Phytohemagglutinin-induced pe-ripheral blood cytogenetics: a valid means for diagnosis and imatinib therapy monitoring of chronic phase chronic myeloid leukemia patients. J Cancer Sci Ther, 7, 242-248. |
29 | Pandolfi PP (2001). In vivo analysis of the molecular genetics of acute promyelocytic leu-kemia. Oncogen, 20, 5726-35. DOI |
30 | Pandolfi PP, Alcalay M, Fagioli M, et al (1992). Genomic variability and alternative splicing generate multiple PML/RARa transcripts that encode aberrant PML proteins and PML/RARa isoforms in acute promyelocytic leukemia. EMBO J, 11, 1397-407. |
31 | Redner RL, Rush EA, Faas S, et al(1996). The t(5;17) variant of acute promyelocytic leu-kemia expresses a nucleophosminretinoic acid receptor fusion. Blood, 87, 882-886. |
32 | Seabrigth M (1971). A rapid banding technique for human chromosomes. Lancet, 2, 971-72. |
33 | Vahdat L, Maslak P, Miller WH Jr, et al(1994). Early mortality and retinoic acid syndrome in acute promyelocytic leukemia: impact of leukocytosis, lowdose chemotherapy, PML/RAR-a isoform, and CD13 expression in patients treated with all-trans retinoid acid. Blood, 84, 3843-3849. |
34 |
Shen A-X, Chen G-Q, Ni J-H, et al(1997). Use of arsenic trioxide ( |
35 | So CC, Wan TS, Chow JL, et al (2011). A single-center cytogenetic study of 629 Chinese patients with de novo acute myeloid leukemia evidence of major ethnic differences and a high prevalence of acute promyelocytic leukemia in Chinese patients. Cancer Genet, 204, 430-8. DOI |
36 | van Dongen JJ, Macintyre EA, Gabert JA, et al (1999). Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of mi-nimal residual disease. Report of the BIOMED-1 Concerted Action investigation of mini-mal residual disease in acute leukemia. Leukemia, 13, 1901-28. DOI |
37 | Villa R, Morey L, Raker VA, et al (2006). The methyl-CpG binding protein MBD1 is requi-red for PML- RARalpha function. Proc Natl Acad Sci U S A, 103, 1400-5. DOI |
38 | Wang AM, Doyle MV, Mont DF (1989). Quantification of mRNA by polymerase chain reac-tion. Proc. Natl Acad Sci USA, 86, 9717-21. DOI |
39 | Warrell RP, Frankel SP, Miller WH, et al(1991). Differentiation therapy of acute promyelo-cytic leukemia with tretinoin (all-t"-retinoic acid). N Engl J Med, 324, 1385-9. DOI |
40 | Warrell R.P. Jr, de The H, Wang ZY, et al (1993). Acute Promyelocytic leukemia. N Eng J Med, 329, 177-89. DOI |
41 | Zhong S, Salomoni P, Pandolfi PP (2000). The transcriptional role of PML and the nuclear body. Nat Cell Biol, 2, 85-90. role of PML and the nuclear body. Nat Cell Biol, 2, 85-90. DOI |
42 | Wells RA, Catzavelos C, Kamel-Reid S (1997). Fusion of retinoic acid receptor a to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute apparatus protein, by a variant translocation in acute promyelocytic leukaemia. Nat Genet, 17,109-113. DOI |
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