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http://dx.doi.org/10.7314/APJCP.2015.16.8.3413

Re-examination of Opisthorchis viverrini Infection in Northeast Thailand  

Yeoh, Kheng-Wei (Department of Public Health, University of Oxford)
Promthet, Supannee (Department of Epidemiology, Faculty of Public Health, Khon Kaen University)
Sithithaworn, Paiboon (Department of Parasitology, Faculty of Medicine, Khon Kaen University)
Kamsaard, Supot (Cancer Unit, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University)
Parkin, Donald Maxwell (Department of Public Health, University of Oxford)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.16, no.8, 2015 , pp. 3413-3418 More about this Journal
Abstract
Background: Liver fluke infection caused by the parasite Opisthorchis viverrini (O. viverrini), a human carcinogen, is endemic in north-eastern Thailand and remains a major health problem. Objectives: The objectives of the study were to (1) resurvey the prevalence of O. viverrini infection in a field site from the Khon Kaen Cohort Study (in newly recruited subjects as well as previous cohort subjects surveyed in 1992); (2) investigate how subjects' lifestyle habits and their exposure to health promotion initiatives influence changes in prevalence of O. viverrini infection. Materials and Methods: The prevalence of O. viverrini infection in the cohort subjects (as well as new subjects) was investigated using faecal egg counts. Information on demographic factors, lifestyle and awareness of health promotion initiatives were obtained through questionnaires. Results: O. viverrini infection rates in the same individuals of the cohort were lower in 2006 than in 1992. Also, by studying the period effect, the current 35-44 year olds had a 12.4% (95% CI 3.9% to 20.9%) lower prevalence of O. viverrini infection than the 35-44 year olds in 1992 (24.2% versus 11.8%). Lifestyle choices showed that smoking and alcohol consumption were associated with an increased chance of acquiring O. viverrini infection with adjusted odds ratios of 10.1 (95%CI 2.4-41.6) and 5.3 (95%CI 1.2-23.0), respectively. Conclusions: Our study has demonstrated that although the prevalence of O. viverrini infection over a 14-year period has decreased, unhealthy lifestyle was common with smoking and alcohol consumption being associated with increased chances of infection, emphasising the double burden of disease which developing countries are facing.
Keywords
Opisthorchis viverrini infection; Cholangiocarcinoma; O. viverrini antibody; lifestyle;
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1 Al-Ghamdi HS and Anil S (2007). Serum antibody levels in smoker and non-smoker Saudi subjects with chronic periodontitis. J Periodontol, 78, 1043-50.   DOI
2 Andrews RH, Sithithaworn P, Petney TN (2008). Opisthorchis viverrini: an underestimated parasite in world health. Trends Parasitol, 24, 497-501.   DOI   ScienceOn
3 Attasara P, Sriplung H (2012). Cancer incidence inThailand. In: Khuhaprema T, Attasara P, Sriplung H, Wianggnon S, Sumitsawan Y, Sangrajrang S, editors. Cancer inThailand. Vol.VI, 2004-2006. Bangkok: Ministry of Public Health, Ministry of Education; 2012. p3-68.
4 Bouvard V, Baan R, Straif K, et al (2009). WHO International Agency for Research on Cancer Monograph Working Group. A review of human carcinogens - Part B. Biological agents. Lancet Oncol, 10, 321-2.   DOI
5 Elkins DB, Sithithaworn P, Haswell-Elkins M, et al (1991). Opisthorchis viverrini: relationships between egg counts, worms recovered and antibody levels within an endemic community in northeast Thailand. Parasitology, 102, 283-8.   DOI
6 Fürst T, Keiser J, Utzinger J (2012). Global burden of human food-borne trematodiasis: a systematic review and metaanalysis. Lancet Infect Dis, 12, 201-21.   DOI
7 Grundy-Warr C, Andrews RH, Sithithaworn P, et al (2012). Raw attitudes, wetland cultures, life cycles: socio-cultural dynamics relating to Opisthorchis viverrini in the Mekong Basin. Parasitology Int, 61, 65-70.   DOI
8 Honjo S, Srivatanakul P, Sriplung H, et al (2005). Genetic and environmental determinants of risk for cholangiocarcinoma via Opisthorchis viverrini in a densely infested area in Nakhon Phanom, northeast Thailand. Int J Cancer, 117, 854-60.   DOI
9 International Agency For Research On Cancer, IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (2012). Biological agents. A review of human carcinogens. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 100, 1-441.
10 Johansen MV, Sithithaworn P, Bergquist R, Utzinger J (2010). Towards improved diagnosis of zoonotic trematode infections in Southeast Asia. Adv Parasitol, 73, 171-95.   DOI   ScienceOn
11 Jongsuksuntigul P, Imsomboon T. 2003. Opisthorchis control in Thailand. Acta Tropica, 88, 229-232.   DOI
12 Parkin DM, Ohshima H, Srivatanakul P, Vatanasapt V (1993). Cholangiocarcinoma: epidemiology, mechanisms of carcinogenesis and prevention. Cancer Epidemiol Biomarkers Prev, 2, 537-44.
13 Kaewpitoon N, Kaewpitoon SJ, Pengsaa P, Chutigan P (2007). Knowledge, attitude and practice related to liver fluke infection in northeast Thailand. World J Gastroenterol, 13, 1837-40.   DOI
14 Murray CJ, Vos T, LozanoR, et al (2012). Disability adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet, 380, 2197-223.   DOI   ScienceOn
15 Parkin DM, Whelan SL, Ferlay J, Teppo L, Thomas DB eds. (2002). Cancer incidence in five continents, Vol.VIII. IARC Scientific Publications No.155. Lyon: International Agency for Research on Cancer.
16 Rhongbutsri P, Kitvatanachai P (2002). Survey of the fluke infection rate in Ban Kok Yai village, Khon Kaen, Thailand. J Trop Med Parasitol, 25, 76-8.
17 Sadun EH (1955). Studies of Opisthorchis viverrini in Thailand. Am J Hyg, 2, 81-115.
18 Saengsawang P, Promthet S, Bradshaw P (2013). Infection with Opisthorchis viverrini and use of praziquantel among a working-age population in northeast Thailand. Asian Pac J Cancer Prev, 14, 2963-6.   DOI   ScienceOn
19 Shang S, Ordway D, Henao-Tamayo M, et al (2011). Cigarette smoke increases susceptibility to tuberculosis-evidence from in vivo and in vitro models. J Infect Dis, 203, 1240-48.   DOI
20 Shin H, Oh J, Masuyer, Curado M, et al (2010). Epidemiology of cholangiocarcinoma: an update focusing on risk factors. Cancer Sci, 101, 579-85.   DOI
21 Sriamporn S, Parkin DM, Pisani P, et al (2005). A prospective study of diet, lifestyle, and genetic factors and the risk of cancer in Khon Kaen province, northeast Thailand: description of the cohort. Asian Pac J Cancer Prev, 6, 295-303.
22 Sithithaworn P (2003). Epidemiology of Opisthorchis viverrini. Acta Tropica, 88, 187-94.   DOI
23 Sithithaworn P, Andrews RH, Nguyen VD, et al (2012). The current status of opisthorchiasis and clonorchiasis in the Mekong Basin. Parasitol Int, 61, 10-6.   DOI
24 Songserm N, Promthet S, Sithithaworn P, et al (2012). Risk factors for cholangiocarcinoma in high-risk area of Thailand:role of lifestyle, diet and methylenetetrahydrofolate reductase polymorphisms. Cancer Epidemol, 36, 89-94.   DOI   ScienceOn
25 Sriamporn S, Pisani P, Pipitgool V, et al (2004). Prevalence of Opisthorchis viverrini infection and incidence of cholangiocarcinoma in Khon Kaen, Northeast Thailand. Trop Med Int Health, 9, 588-94.   DOI
26 Sriraj P, Aukkanimart R, Boobmars T, et al (2013). Alcohol and alkalosis enhance excystation of Opisthorchis viverrini metacercariae. Parasitol Res, 112, 2397-402.   DOI
27 Sripa B, Pairojkul C (2008). Cholangiocarcinoma: lessons from Thailand. Curr Opin Gastroenterol, 24, 349-56.   DOI   ScienceOn
28 Sripa B, Tangkawattana S, Laha T, et al (2015). Toward integrated opisthorchiasis control in northeast Thailand: The Lawa project. Acta Trop, 141, 361-67.   DOI
29 StataCorp LP (2007). Stata Release 10: User's guide. College Station TX: Stata Press.
30 Thammapalerd N, Tharavanji S, Nacapunchai D, et al (1988). Detection of antibodies against Opisthorchis viverrini in pateints before and after treatment with praziquantel. Southeast Asian J Trop Med Pub Health, 19, 101-8.
31 Thaewnongiew K, Singthong S, Kutchamart S, et al (2014). Prevalence and risk factors for Opisthorchis viverrini infections in upper Northeast Thailand. Asian Pac J Cancer Prev, 15, 6609-12.   DOI
32 Upatham ES, Viyanant V (2003). Opisthorchis viverrini and opisthorchiasis: a historical review and future perspective. Acta Trop, 88, 171-6.   DOI
33 Upatham ES, Viyanant V, Brockelman WY, et al (1988). Rate of re-infection by Opisthorchis viverrini in an endemic northeast Thai community after chemotherapy. Int J Parasitol, 18, 643-69.   DOI
34 Vatanasapt V, Pengsaa P, Tangvoraphonkchai V, et al (1992). Thailand: Khon Kaen Cancer Registry. In Parkin DM, Muir CS, Whelan SL, Gao TT, Ferlay J and Powell J (eds). Cancer incidence in five continents, Vol. VI. IARC Scientific Publications No. 120, pp 546-549. Lyon: International Agency for Research on Cancer.
35 Wang H, Zhou H, Mahler S, et al (2011). Alcohol affects the late differentiation of progenitor B cells. Alcohol and Alcoholism, 46, 26-32.   DOI
36 WHO (1995). Control of foodborne trematode infection. WHO technical report series, 849.
37 Wykoff DE, Harinasuta C, Juttijudata P, Winn MM (1965). Opisthorchis viverrini in Thailand-the life cycle and comparison with O. felineus. J Parasitol, 51, 207-14.   DOI