Autophagy in Tumorigenesis and Cancer Treatment |
Xu, Dong-Wei
(Department of Chinese Minority Traditional Medicine, Minzu University of China)
Zhang, Guan-Qing (Department of Chinese Minority Traditional Medicine, Minzu University of China) Wang, Zong-Wei (Department of Urology, Massachusetts General Hospital) Xu, Xiao-Yin (Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School) Liu, Tong-Xiang (Department of Chinese Minority Traditional Medicine, Minzu University of China) |
1 | Aguirre-Ghiso JA (2006). The problem of cancer dormancy: understanding the basic mechanisms and identifying therapeutic opportunities. Cell Cycle, 5, 1740-3. DOI |
2 | Ahn CH, Jeong EG, Lee JW, et al (2007). Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers. APMIS, 115, 1344-9. DOI |
3 | Apetoh L, Ghiringhelli F, Tesniere A, et al (2007). Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med, 13, 1050-9. DOI |
4 | Chen BL, Wang LT, Huang KH, et al (2014). Quercetin attenuates renal ischemia/reperfusion injury via an activation of AMP-activated protein kinase-regulated autophagy pathway. J Nutr Biochem, 25, 1226-34 DOI |
5 | Chen F, Sun ZW, Ye LF, et al (2014). Lycopene protects against apoptosis in hypoxia/reoxygenationinduced H9C2 myocardioblast cells through increased autophagy. Mol Med Rep, 11, 1358-65. |
6 | Eisenberg-Lerner A, Kimchi A (2009). The paradox of autophagy and its implication in cancer etiology and therapy. Apoptosis, 14, 376-91. DOI |
7 | Galluzzi L, Vitale I, Abrams JM, et al (2012). Molecular definitions of cell death subroutines: recommendations of the nomenclature committee on cell death 2012. Cell Death Differ, 19, 107-20. DOI |
8 | Geng J, Baba M, Nair U, Klionsky DJ (2008). Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy. J Cell Biol, 182, 129-40. DOI |
9 | Ghayad SE, Cohen PA(2010). Inhibitors of the PI3K/Akt/mTOR pathway: new hope for breast cancer patients. Recent Pat Anticancer Drug Discov, 5, 29-57. DOI |
10 | Gozuacik D, Kimchi A (2004). Autophagy as a cell death and tumor suppressor mechanism. Oncogene, 23, 2891-906. DOI |
11 | Hanahan D, Weinberg RA (2011). Hallmarks of cancer: the next generation. Cell, 144, 646-74. DOI |
12 | He J, Wang Y, Xu LH et al (2013). Cucurbitacin IIa induces caspase-3-dependent apoptosis and enhances autophagy in lipopolysaccharide-stimulated RAW 264.7 macrophages. Int Immunopharmacol, 16, 27-34. DOI |
13 | Hotchkiss RS, Strasser A, McDunn JE, Swanson PE (2009). Cell death. N Engl J Med, 361, 1570-83. DOI |
14 | Huang J, Klionsky DJ (2007). Autophagy and human disease. Cell Cycle, 6, 1837-49. DOI |
15 | Inoki K, Guan KL (2009). Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatment. Hum Mol Genet, 18, 94-100. DOI |
16 | Jaber N, Zong WX (2013). Class III PI3K Vps34: essential roles in autophagy, endocytosis, and heart and liver function. Ann N Y Acad Sci, 1280, 48-51. DOI |
17 | Lee JW, Jeong EG, Soung YH, et al (2006). Decreased expression of tumour suppressor Bax-interacting factor-1 (Bif-1), a Bax activator, in gastric carcinomas. Pathology, 38, 312-5. DOI |
18 | Klionsky DJ, Cregg JM, Dunn WA, et al (2003). A unified nomenclature for yeast autophagy-related genes. Dev Cell, 5, 539-45. DOI |
19 | Koneri K, Goi T, Hirono Y, Katayama K, Yamaguchi A (2007). Beclin 1 gene inhibits tumor growth in colon cancer cell lines. Anticancer Res, 27, 1453-7. |
20 | Lee JS, Li Q, Lee JY, et al (2009). FLIP-mediated autophagy regulation in cell death control. Nat Cell Biol, 11, 1355-62. DOI |
21 | Levine B (2007). Cell biology: autophagy and cancer. Nature, 446, 745-7. DOI |
22 | Levine B, Abrams J (2008). p53: The janus of autophagy? Nat Cell Biol, 10, 637-9. DOI |
23 | Li J L, Han SL, Fan X (2011). Modulating autophagy: a strategy for cancer therapy. Chin J Cancer, 30, 655-68. DOI |
24 | Liang XH, Jackson S, Seaman M, et al (1999). Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature, 402, 672-6. DOI |
25 | Lv XC, Zhou HY (2012). Resveratrol protects H9c2 embryonic rat heart derived cells from oxidative stress by inducing autophagy: role of p38 mitogen-activated protein kinase. Can J Physiol Pharmacol, 90, 655-62. DOI |
26 | Maiuri MC, Malik SA, Morselli E, et al (2009). Stimulation of autophagy by the p53 target gene Sestrin2. Cell Cycle, 8, 1571-6. DOI |
27 | Maiuri MC, Tasdemir E, Criollo A, et al (2009). Control of autophagy by oncogenes and tumor suppressor genes. Cell Death Differ, 16, 87-93. DOI |
28 | Wei Y, Zou Z, Becker N, et al (2013). EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance. Cell, 154, 1269-84. DOI |
29 | Wang C, Zhang X, Teng Z, Zhang T, Li Y (2014). Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice. Eur J Pharmacol, 740, 312-20. DOI |
30 | Wang Z, Zhang J, Wang Y, et al (2013). Matrine, a novel autophagy inhibitor, blocks trafficking and the proteolytic activation of lysosomal proteases. Carcinogenesis, 34, 128-38. DOI |
31 | White E, Karp C, Strohecker AM, Guo Y, Mathew R (2010). Role of autophagy in suppression of inflammation and cancer. Curr Opin Cell Biol, 22, 212-7. DOI |
32 | White EJ, Martin V, Liu JL, et al (2011). Autophagy regulation in cancer development and therapy. Am J Cancer Res, 1, 362-72. |
33 | Yang YL, Ji C, Bi ZG, et al (2013). Deguelin induces both apoptosis and autophagy in cultured head and neck squamous cell carcinoma cells. PLoS One, 8, 54736. DOI |
34 | Yang Z, Klionsky DJ (2009). An overview of the molecular mechanism of autophagy. Curr Top Microbiol Immunol, 335, 1-32. |
35 | Yang ZJ, Chee CE, Huang S, Sinicrope F (2011). Autophagy modulation for cancer therapy. Cancer Biol Ther, 11, 169-76. DOI |
36 | Yorimitsu T, Klionsky DJ (2005). Autophagy: molecular machinery for self-eating. Cell Death Differ, 12, 1542-52. DOI |
37 | Yuan G, Yan SF, Xue H, et al (2014). Cucurbitacin I induces protective autophagy in glioblastoma in vitro and in vivo. J Biol Chem, 289, 10607-19. DOI |
38 | Choi CH, Jung YK, Oh SH (2010). Autophagy induction by capsaicin in malignant human breast cells is modulated by p38 and extracellular signal-regulated mitogen-activated protein kinases and retards cell death by suppressing endoplasmic reticulum stress-mediated apoptosis. Mol Pharmacol, 78, 114-25. DOI |
39 | Zhang EB, Yin DD, Sun M, et al (2014). P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression. Cell Death Dis, 5, 1243. DOI |
40 | Zhu JS, Ouyang DY, Shi ZJ (2012). Cucurbitacin B induces cell cycle arrest, apoptosis and autophagy associated with G actin reduction and persistent activation of cofilin in Jurkat cells. Pharmacology, 89, 348-56. DOI |
41 | Choi MS, Kim Y, Jung JY, et al (2013). Resveratrol induces autophagy through death-associated protein kinase 1 (DAPK1) in human dermal fibroblasts under normal culture conditions. Exp Dermatol, 22, 491-4. DOI |
42 | Copetti T, Bertoli C, Dalla E, Demarchi F, Schneider C(2009). p65/RelA modulates BECN1 transcription and autophagy. Mol Cell Biol, 29, 2594-608. DOI |
43 | D'Amelio M, Cecconi F (2009). A novel player in the p53-mediated autophagy: Sestrin2. Cell Cycle, 8, 1467. |
44 | De Duve C, Pressman BC, Gianetto R, Wattiaux R, Appelmans F (1955). Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue. Biochem J, 60, 604-17. DOI |
45 | Degenhardt K, Mathew R, Beaudoin B, et al (2006). Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell, 10, 51-64. DOI |
46 | DiPaola RS, Dvorzhinski D, Thalasila A, et al (2008). Therapeutic starvation and autophagy in prostate cancer: a new paradigm for targeting metabolism in cancer therapy. Prostate, 68, 1743-52. DOI |
47 | Djavaheri-Mergny M, Amelotti M, Mathieu J, et al (2006). NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy. J Biol Chem, 281, 30373-82. DOI ScienceOn |
48 | Du J, An J, Wei N, et al (2010). Increased resistance to LPS-induced myocardial dysfunction in the Brown Norway rats versus Dahl S rats: roles of inflammatory cytokines and nuclear factor kappaB pathway. Shock, 33, 332-6. DOI |
49 | Kang MR, Kim MS, Oh JE, et al (2009). Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability. J Pathol, 217, 702-6. DOI |
50 | Jiang H, Martin V, Gomez-Manzano C, et al (2010). The RB-E2F1 pathway regulates autophagy. Cancer Res, 70, 7882-93. DOI |
51 | Karantza-Wadsworth V, Patel S, Kravchuk O, et al (2007). Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev, 21, 1621-35. DOI |
52 | Karantza-Wadsworth V, White E (2007). Role of autophagy in breast cancer. Autophagy, 3, 610-3. DOI |
53 | Karin M (2006). Nuclear factor-kappaB in cancer development and progression. Nature, 441, 431-6. DOI ScienceOn |
54 | Kenific CM, Debnath J (2014). Cellular and metabolic functions for autophagy in cancer cells. Trends Cell Biol, 25, 37-45. |
55 | Khan KH, Yap TA, Yan L, Cunningham D (2013). Targeting the PI3K-AKT-mTOR signaling network in cancer. Chin J Cancer, 32, 253-65. DOI |
56 | Kim SY, Oh YL, Kim KM, et al (2008). Decreased expression of Bax-interacting factor-1 (Bif-1) in invasive urinary bladder and gallbladder cancers. Pathology, 40, 553-7. DOI |
57 | Klionsky DJ(2005). The molecular machinery of autophagy: unanswered questions. J Cell Sci, 118, 7-18. DOI |
58 | Klionsky DJ (2007). Autophagy: from phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol, 8, 931-7. DOI |
59 | Klionsky DJ (2014). Citing recent declines in the discovery of new ATG genes, some scientists now suggest that the end of autophagy research may be within sight. Autophagy, 10, 715-6. DOI |
60 | Massey A, Kiffin R, Cuervo AM (2004). Pathophysiology of chaperone-mediated autophagy. Int J Biochem Cell Biol, 36, 2420-34. DOI |
61 | Mizushima N, Levine B, Cuervo AM, Klionsky DJ (2008). Autophagy fights disease through cellular self-digestion. Nature, 451, 1069-75. DOI |
62 | Morselli E, Galluzzi L, Kepp O, et al (2009). Anti- and pro-tumor functions of autophagy. Biochim Biophys Acta, 1793, 1524-32. DOI |
63 | O'Prey J, Skommer J, Wilkinson S, Ryan KM (2009). Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy. Cell Cycle, 8, 2260-5. DOI |
64 | Ohsumi Y (2006). Autophagy related genes in yeast, S. cerevisiae. Tanpakushitsu Kakusan Koso, 51, 1453-6. |
65 | Opipari AW, Jr, Tan L, et al (2004). Resveratrol-induced autophagocytosis in ovarian cancer cells. Cancer Res, 64, 696-703. DOI |
66 | Pal S, Bhattacharyya S, Choudhuri T, et al (2005). Amelioration of immune cell number depletion and potentiation of depressed detoxification system of tumor-bearing mice by curcumin. Cancer Detect Prev, 29, 470-8. DOI |
67 | Qu X, Yu J, Bhagat G, et al (2003). Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest, 112, 1809-20. DOI ScienceOn |
68 | Rosenfeldt MT, Ryan KM (2009). The role of autophagy in tumour development and cancer therapy. Expert Rev Mol Med, 11, 36. DOI ScienceOn |
69 | Rosenfeldt MT, Ryan KM (2011). The multiple roles of autophagy in cancer. Carcinogenesis, 32, 955-63. DOI |
70 | Rufini A, Melino G (2011). Cell death pathology: the war against cancer. Biochem Biophys Res Commun, 414, 445-50. DOI |
71 | Soussi T, Wiman KG (2007). Shaping genetic alterations in human cancer: the p53 mutation paradigm. Cancer Cell, 12, 303-12. DOI |
72 | Scherz-Shouval R, Shvets E, Fass E, et al (2007). Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J, 26, 1749-60. DOI |
73 | Shen Y, Li DD, Wang LL, Deng R, Zhu XF (2008). Decreased expression of autophagy-related proteins in malignant epithelial ovarian cancer. Autophagy, 4, 1067-8. DOI |
74 | Shi Z, Li CY, Zhao S, et al (2013). A systems biology analysis of autophagy in cancer therapy. Cancer Lett, 337, 149-60. DOI |
75 | Sui X, Jin L, Huang X, et al (2011). p53 signaling and autophagy in cancer: a revolutionary strategy could be developed for cancer treatment. Autophagy, 7, 565-71. DOI |
76 | Sun Q, Fan W, Zhong Q (2009). Regulation of Beclin 1 in autophagy. Autophagy, 5, 713-6. DOI |
77 | Takahashi Y, Meyerkord CL, Wang HG (2009). Bif-1/endophilin B1: a candidate for crescent driving force in autophagy. Cell Death Differ, 16, 947-55. DOI |
78 | Tanida I, Ueno T, Kominami E (2004). LC3 conjugation system in mammalian autophagy. Int J Biochem Cell Biol, 36, 2503-18. DOI |
79 | Tasdemir E, Maiuri MC, Galluzzi L, et al (2008). Regulation of autophagy by cytoplasmic p53. Nat Cell Biol, 10, 676-87. DOI |
80 | Tu QQ, Zheng RY, Li J, et al (2014). Palmitic acid induces autophagy in hepatocytes via JNK2 activation. Acta Pharmacol Sin, 35, 504-12. DOI |
81 | Van Waes C (2007). Nuclear factor-kappaB in development, prevention, and therapy of cancer. Clin Cancer Res, 13, 1076-82. DOI |