Hep88 mAb-Mediated Paraptosis-Like Apoptosis in HepG2 Cells via Downstream Upregulation and Activation of Caspase-3, Caspase-8 and Caspase-9 |
Mitupatum, Thantip
(Faculty of Medicine, Thammasat University (Rangsit Campus))
Aree, Kalaya (Faculty of Medicine, Thammasat University (Rangsit Campus)) Kittisenachai, Suthathip (Thailand National Center for Genetic Engineering and Biotechnology (BIOTEC), Thailand Science Park) Roytrakul, Sittiruk (Thailand National Center for Genetic Engineering and Biotechnology (BIOTEC), Thailand Science Park) Puthong, Songchan (Antibody Production Research Unit, Institute of Biotechnology and Genetic Engineering, Chulalongkorn University) Kangsadalampai, Sasichai (Faculty of Medicine, Thammasat University (Rangsit Campus)) Rojpibulstit, Panadda (Faculty of Medicine, Thammasat University (Rangsit Campus)) |
1 | Rojpibulstit P, Kittisenachai S, Puthong S, et al (2014). Hep88 mAb-initiated paraptosis-like PCD pathway in hepatocellular carcinoma cell line through the binding of mortalin (HSPA9) and alpha-enolase. Cancer Cell Int, 14, 69-78. DOI |
2 | Ruchalski K, Mao H, Li Z, et al (2006). Distinct hsp70 domains mediate apoptosis-inducing factor release and nuclear accumulation. J Biol Chem, 281, 7873-80. DOI |
3 | Sabirzhanov B, Stoica BA, Hanscom M, et al (2012). Overexpression of HSP70 attenuates caspase-dependent and caspase-independent pathways and inhibits neuronal apoptosis. J Neurochem, 123, 542-54. DOI |
4 | Selim ME, Hendi AA (2012). Gold nanoparticles induce apoptosis in MCF-7 human breast cancer cells. Asian Pac J Cancer Prev, 13, 1617-20. DOI ScienceOn |
5 | Somboon K, Siramolpiwat S, Vilaichone RK (2014). Epidemiology and survival of hepatocellular carcinoma in the central region of Thailand. Asian Pac J Cancer Prev, 15, 3567-70. DOI ScienceOn |
6 | Sperandio S, de Belle I, Bredesen DE (2000). An alternative, nonapoptotic form of programmed cell death. Proc Natl Acad Sci U S A, 97, 14376-81. DOI |
7 | Sreedhar AS, Csermely P (2004). Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy: a comprehensive review. Pharmacol Ther, 101, 227-57. DOI |
8 | Unal-Cevik I, Kilinc M, Can A, et al (2004). Apoptotic and necrotic death mechanisms are concomitantly activated in the same cell after cerebral ischemia. Stroke, 35, 2189-94. DOI |
9 | Wadhwa R, Taira K, Kaul SC (2002). An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: what, when, and where? Cell Stress Chaperones, 7, 309-16. DOI |
10 | Wadhwa R, Takano S, Kaur K, et al (2006). Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis. Int J Cancer, 118, 2973-80. DOI |
11 | Wyllie AH, Golstein P (2001). More than one way to go. Proc Natl Acad Sci USA, 98, 11-3. DOI |
12 | Yang JD, Roberts LR (2010a). Epidemiology and management of hepatocellular carcinoma. Infect Dis Clin North Am, 24, 899-919. DOI |
13 | Yang JD, Roberts LR (2010b). Hepatocellular carcinoma: A global view. Nat Rev Gastroenterol Hepatol, 7, 448-58. DOI |
14 | Yu J, Zhou X, He X, et al (2011). Curcumin induces apoptosis involving bax/bcl-2 in human hepatoma SMMC-7721 cells. Asian Pac J Cancer Prev, 12, 1925-9. |
15 | Zhu Q, Xu YM, Wang LF, et al (2009). Heat shock protein 70 silencing enhances apoptosis inducing factor-mediated cell death in hepatocellular carcinoma HepG2 cells. Cancer Biol Ther, 8, 792-8. DOI |
16 | Cande C, Cohen I, Daugas E, et al (2002). Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria. Biochimie, 84, 215-22. DOI |
17 | Al-Fatlawi AA, Al-Fatlawi AA, Irshad M, et al (2014). Rice bran phytic acid induced apoptosis through regulation of Bcl-2/Bax and p53 genes in HepG2 human hepatocellular carcinoma cells. Asian Pac J Cancer Prev, 15, 3731-6. DOI |
18 | Beere HM (2004). "The stress of dying": the role of heat shock proteins in the regulation of apoptosis. J Cell Sci, 117, 2641-51. DOI |
19 | Bursch W (2001). The autophagosomal-lysosomal compartment in programmed cell death. Cell Death Differ, 8, 569-81. DOI |
20 | Cho S, Lee JH, Cho SB, et al (2010). Epigenetic methylation and expression of caspase 8 and survivin in hepatocellular carcinoma. Pathol Int, 60, 203-11. DOI |
21 | Del Puerto HL, Martins AS, Moro L, et al (2010). Caspase-3/-8/-9, Bax and Bcl-2 expression in the cerebellum, lymph nodes and leukocytes of dogs naturally infected with canine distemper virus. Genet Mol Res, 9, 151-61. DOI |
22 | Chua CW, Choo SP (2011). Targeted therapy in hepatocellular carcinoma. Int J Hepatol, 2011, 348297. |
23 | Ciocca DR, Calderwood SK (2005). Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications. Cell Stress Chaperones, 10, 86-103. DOI |
24 | Daugaard M, Rohde M, Jaattela M (2007). The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions. FEBS Lett, 581, 3702-10. DOI |
25 | Deocaris CC, Widodo N, Ishii T, et al (2007). Functional significance of minor structural and expression changes in stress chaperone mortalin. Ann N Y Acad Sci, 1119, 165-75. DOI |
26 | Ferlay J, Shin HR, Bray F, et al (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer, 127, 2893-917. DOI |
27 | Garrido C, Gurbuxani S, Ravagnan L, et al (2001). Heat shock proteins: endogenous modulators of apoptotic cell death. Biochem Biophys Res Commun, 286, 433-42. DOI |
28 | Guo WJ, Chen TS, Wang XP, et al (2010). Taxol induces concentration-dependent apoptotic and paraptosis-like cell death in human lung adenocarcinoma (ASTC-a-1) cells. J Xray Sci Technol, 18, 293-308. |
29 | Gupta RK, Banerjee A, Pathak S, et al (2013). Induction of mitochondrial-mediated apoptosis by Morinda citrifolia (Noni) in human cervical cancer cells. Asian Pac J Cancer Prev, 14, 237-42. DOI ScienceOn |
30 | Gupta S, Kass GE, Szegezdi E, et al (2009). The mitochondrial death pathway: a promising therapeutic target in diseases. J Cell Mol Med, 13, 1004-33. DOI ScienceOn |
31 | Ho M (2011). Advances in liver cancer antibody therapies: a focus on glypican-3 and mesothelin. BioDrugs, 25, 275-84. DOI |
32 | Jia ZQ, Chen Y, Yan YX, et al (2014). Iso-suillin isolated from Suillus luteus, induces G1 phase arrest and apoptosis in human hepatoma SMMC-7721 cells. Asian Pac J Cancer Prev, 15, 1423-8. DOI |
33 | Jiang L, Liu M, Li Y, et al (2014). Abstract 1559: TTC36, a novel chaperone of heat shock protein 70, functions as a tumor suppressor in hepatocellular carcinoma. Cancer Res, 74, 1559. DOI |
34 | Kaul SC, Deocaris CC, Wadhwa R (2007). Three faces of mortalin: a housekeeper, guardian and killer. Exp Gerontol, 42, 263-74. DOI |
35 | Laohathai K, Bhamarapravati N (1985). Culturing of human hepatocellular carcinoma. A simple and reproducible method. Am J Pathol, 118, 203-8. |
36 | Leist M, Jaattela M (2001). Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol, 2, 589-98. |
37 | Li B, Zhao J, Wang CZ, et al (2011). Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53. Cancer Lett, 301, 185-92. DOI |
38 | Li GN, Wang SP, Xue X, et al (2013). Monoclonal antibodyrelated drugs for cancer therapy. Drug Discov Ther, 7, 178-84. |
39 | Lu WJ, Lee NP, Kaul SC, et al (2011). Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy. Cell Death Differ, 18, 1046-56. DOI |
40 | Ma Z, Izumi H, Kanai M, et al (2006). Mortalin controls centrosome duplication via modulating centrosomal localization of p53. Oncogene, 25, 5377-90. DOI |
41 | Manochantr S, Puthong S, Gamnarai P, et al (2011). Hep 88 mAB induced ultrastructural alteration through apoptosis like program cell death in hepatocellular carcinoma. J Med Assoc Thai, 94, 109-16. |
42 | Norberg E, Orrenius S, Zhivotovsky B (2010). Mitochondrial regulation of cell death: processing of apoptosis-inducing factor (AIF). Biochem Biophys Res Commun, 396, 95-100. DOI |
43 | Osaki Y, Nishikawa H (2014). Treatment for hepatocellular carcinoma in Japan over the last three decades: Our experience and published work review. Hepatol Res. |
44 | Pfaffl MW, Hageleit M (2001). Validities of mRNA quantification using recombinant RNA and recombinant DNA external calibration curves in real-time RT-PCR. Biotechnology Letters, 23, 275-82. DOI |
45 | Puthong S, Rojpibulstit P, Buakeaw A (2009). Cytotoxic effect of Hep88 mAb: a novel monoclonal antibody against hepatocellular carcinoma. Thammasat Int J Sc Tech, 14, 95-104. |
46 | Qu M, Zhou Z, Chen C, et al (2012). Inhibition of mitochondrial permeability transition pore opening is involved in the protective effects of mortalin overexpression against betaamyloid- induced apoptosis in SH-SY5Y cells. Neurosci Res, 72, 94-102. DOI |
47 | Ravagnan L, Gurbuxani S, Susin SA, et al (2001). Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol, 3, 839-43. DOI |
48 | Rohde M, Daugaard M, Jensen MH, et al (2005). Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms. Genes Dev, 19, 570-82. DOI |