Protective Effect of Astragalus polysaccharides on Liver Injury Induced by Several Different Chemotherapeutics in Mice |
Liu, Wen
(Department of Pathology and Pathophysiology, Research Center of Food and Drug Evaluation, School of Medicine, Wuhan University)
Gao, Fang-Fang (Department of Pathology and Pathophysiology, Research Center of Food and Drug Evaluation, School of Medicine, Wuhan University) Li, Qun (Renmin Hospital of Wuhan University, the First College of Clinical Medicine of Wuhan University) Lv, Jia-Wei (Zhongnan Hospital of Wuhan University, the Second College of Clinical Medicine of Wuhan University) Wang, Ying (Department of Pathology and Pathophysiology, Research Center of Food and Drug Evaluation, School of Medicine, Wuhan University) Hu, Peng-Chao (Department of Pathology and Pathophysiology, Research Center of Food and Drug Evaluation, School of Medicine, Wuhan University) Xiang, Qing-Ming (Zhongnan Hospital of Wuhan University, the Second College of Clinical Medicine of Wuhan University) Wei, Lei (Department of Pathology and Pathophysiology, Research Center of Food and Drug Evaluation, School of Medicine, Wuhan University) |
1 | Anonymous (2003). Astragalus membranaceus. Monograph. Altern Med Rev, 8, 72-7. |
2 | Al-Sayed E, Martiskainen O, Seif el-Din SH, et al (2014). Hepatoprotective and antioxidant effect of Bauhinia hookeri extract against carbon tetrachloride-induced hepatotoxicity in mice and characterization of its bioactive compounds by HPLC-PDA-ESI-MS/MS. Biomed Res Int, 2014, 245171. |
3 | Alexandre J, Bleuzen P, Bonneterre J, et al (2000). Factors predicting for efficacy and safety of docetaxel in a compassionate-use cohort of 825 heavily pretreated advanced breast cancer patients. J Clin Oncol, 18, 562-73. |
4 | Basu A, Bhattacharjee A, Roy SS, et al (2014). Vanadium as a chemoprotectant: effect of vanadium (III)-L-cysteine complex against cyclophosphamide-induced hepatotoxicity and genotoxicity in Swiss albino mice. J Biol Inorg Chem, 19, 981-96. DOI |
5 | Bissery MC, Nohynek G, Sanderink GJ, et al (1995). Docetaxel (Taxotere): a review of preclinical and clinical experience. Part I: Preclinical experience. Anticancer Drugs, 6, 63-8. DOI |
6 | Chen X, Ye G, Zhang C, et al (2013). Superior outcome after neoadjuvant chemotherapy with docetaxel, anthracycline, and cyclophosphamide versus docetaxel plus cyclophosphamide: results from the NATT trial in triple negative or HER2 positive breast cancer. Breast Cancer Res Treat, 142, 549-58. DOI |
7 | de Jonge ME, Huitema AD, Beijnen JH, et al (2006). High exposures to bioactivated cyclophosphamide are related to the occurrence of veno-occlusive disease of the liver following high-dose chemotherapy. Br J Cancer, 94, 1226-30. DOI |
8 | Ding Y, Zhao L, Mei H, et al (2008). Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway. Eur J Pharmacol, 590, 377-86. DOI |
9 | Dobbs NA, Twelves CJ, Gregory W, et al (2003). Epirubicin in patients with liver dysfunction: development and evaluation of a novel dose modification scheme. Eur J Cancer, 39, 580-6. DOI |
10 | Fan L, Strasser-Weippl K, Li JJ, et al (2014). Breast cancer in China. Lancet Oncol, 15, e279-89. DOI |
11 | Fang Y, Wang L, Xia GH, et al (2014). Clinical investigation of efficacy of albumin bound paclitaxel plus platinum compounds as first-line chemotherapy for stage III/IV squamous non-small cell lung cancer. Asian Pac J Cancer Prev, 15, 7453-7. DOI |
12 | Field KM, Dow C, Michael M (2008). Part I: Liver function in oncology: biochemistry and beyond. Lancet Oncol, 9, 1092-101. DOI |
13 | Joerger M (2014). Metabolism of the taxanes including nabpaclitaxel. Expert Opin Drug Metab Toxicol, 1-12 [Epub ahead of print]. |
14 | Fisher B, Brown AM, Dimitrov NV, et al (1990). Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, methotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifennonresponsive tumors: results from the National Surgical Adjuvant Breast and Bowel Project B-15. J Clin Oncol, 8, 1483-96. |
15 | Horton AA, Fairhurst S (1987). Lipid peroxidation and mechanisms of toxicity. Crit Rev Toxicol, 18, 27-79. DOI |
16 | Jia R, Cao L, Xu P, et al (2012). In vitro and in vivo hepatoprotective and antioxidant effects of Astragalus polysaccharides against carbon tetrachloride-induced hepatocyte damage in common carp (Cyprinus carpio). Fish Physiol Biochem, 38, 871-81. DOI |
17 | Kebieche M, Lakroun Z, Lahouel M, et al (2009). Evaluation of epirubicin-induced acute oxidative stress toxicity in rat liver cells and mitochondria, and the prevention of toxicity through quercetin administration. Exp Toxicol Pathol, 61, 161-7. DOI |
18 | King PD, Perry MC (2001). Hepatotoxicity of chemotherapy. Oncologist, 6, 162-76. DOI |
19 | Liu X, Yang Y, Zhang X, et al (2010). Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-beta/Smad in HepG2 cell. J Gastroenterol Hepatol, 25, 420-6. DOI |
20 | Lu AF, Qi MJ, Li ZL, et al (2010). Callus cultivation and determination of flavonoids from Tetrastigma hemsleyanum. Zhong Yao Cai, 33, 1042-5. |
21 | Lubgan D, Marczak A, Walczak M, et al (2006). Pharmacological mechanisms of Doxorubicin activity (DOX)-current state of knowledge. Przegl Lek, 63, 782-8. |
22 | McDonald GB, Slattery JT, Bouvier ME, et al (2003). Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation. Blood, 101, 2043-8. DOI |
23 | Ma B, Yeo W, Hui P, et al (2002a). Acute toxicity of adjuvant doxorubicin and cyclophosphamide for early breast cancer-a retrospective review of Chinese patients and comparison with an historic Western series. Radiother Oncol, 62, 185-9. DOI |
24 | Ma XQ, Shi Q, Duan JA, et al (2002b). Chemical analysis of Radix Astragali (Huangqi) in China: a comparison with its adulterants and seasonal variations. J Agric Food Chem, 50, 4861-6. DOI |
25 | Matovina-Brko G, Ruzic M, Fabri M, et al (2014). Treatment of acute hepatitis C in breast cancer patient: a case report. J Chemother, 26, 180-3. DOI |
26 | McQuade JL, Meng Z, Chen Z, et al (2012). Utilization of and Attitudes towards Traditional Chinese Medicine Therapies in a Chinese Cancer Hospital: A Survey of Patients and Physicians. Evid Based Complement Alternat Med, 2012, 504507. |
27 | Murialdo R, Gallo M, Boy D, et al (2014). Sequential dose-dense 5-fluorouracil, epirubicin and cyclophosphamide followed by docetaxel in patients with early breast cancer with four or more positive lymph nodes. Tumori, 100, 128-35. |
28 | Na D, Liu FN, Miao ZF, et al (2009). Astragalus extract inhibits destruction of gastric cancer cells to mesothelial cells by anti-apoptosis. World J Gastroenterol, 15, 570-7. DOI |
29 | Naume B, Synnestvedt M, Falk RS, et al (2014). Clinical outcome with correlation to disseminated tumor cell (DTC) status after DTC-guided secondary adjuvant treatment with docetaxel in early breast cancer. J Clin Oncol, 32, 3848-57. DOI |
30 | Ozben T (2007). Oxidative stress and apoptosis: impact on cancer therapy. J Pharm Sci, 96, 2181-96. DOI |
31 | Peng X, Chen B, Lim CC, et al (2005). The cardiotoxicology of anthracycline chemotherapeutics: translating molecular mechanism into preventative medicine. Mol Interv, 5, 163-71. DOI |
32 | Shin HJ, Lee HS, Kim YI, et al (2014). Hepatotoxicity of antituberculosis chemotherapy in patients with liver cirrhosis. Int J Tuberc Lung Dis, 18, 347-51. DOI |
33 | Shokrzadeh M, Naghshvar F, Ahmadi A, et al (2014). The potential ameliorative effects of melatonin against cyclophosphamide-induced DNA damage in murine bone marrow cells. Eur Rev Med Pharmacol Sci, 18, 605-11. |
34 | Thatishetty AV, Agresti N, O'Brien CB (2013). Chemotherapyinduced hepatotoxicity. Clin Liver Dis, 17, 671-86. DOI |
35 | Tian QE, Li HD, Yan M, et al (2012). Astragalus polysaccharides can regulate cytokine and P-glycoprotein expression in H22 tumor-bearing mice. World J Gastroenterol, 18, 7079-86. DOI |
36 | Varbiro G, Veres B, Gallyas F, et al (2001). Direct effect of Taxol on free radical formation and mitochondrial permeability transition. Free Radic Biol Med, 31, 548-58. DOI |
37 | Wang XH, Jia HL, Deng L, et al (2014). Astragalus polysaccharides mediated preventive effects on bronchopulmonary dysplasia in rats. Pediatr Res, 76, 347-54. DOI |
38 | Yang B, Xiao B, Sun T (2013). Antitumor and immunomodulatory activity of Astragalus membranaceus polysaccharides in H22 tumor-bearing mice. Int J Biol Macromol, 62, 287-90. DOI |
39 | Yeo W, Mok TS, Tse KK, et al (2002). Phase II study of docetaxel and epirubicin in Chinese patients with metastatic breast cancer. Anticancer Drugs, 13, 655-62. DOI |
40 | Zhao LH, Ma ZX, Zhu J, et al (2011). Characterization of polysaccharide from Astragalus radix as the macrophage stimulator. Cell Immunol, 271, 329-34. DOI |
![]() |