Low Expression of the FoxO4 Gene may Contribute to the Phenomenon of EMT in Non-small Cell Lung Cancer |
Xu, Ming-Ming
(Department of Cardiothoracic Surgery, Affiliated Hospital of Nantong University)
Mao, Guo-Xin (Department of Oncology, Affiliated Hospital of Nantong University) Liu, Jian (Department of Oncology, Affiliated Hospital of Nantong University) Li, Jian-Chao (Department of Cardiothoracic Surgery, Affiliated Hospital of Nantong University) Huang, Hua (Department of Pathology, Affiliated Hospital of Nantong University) Liu, Yi-Fei (Department of Pathology, Affiliated Hospital of Nantong University) Liu, Jun-Hua (Department of Cardiothoracic Surgery, Affiliated Hospital of Nantong University) |
1 | Tran H, Brunet A, Grenier JM, et al (2002). DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science, 296, 530-4. DOI ScienceOn |
2 | Xu B, Jin DY, Lou WH, Wang DS (2013). Lipocalin-2 is associated with a good prognosis and reversing epithelial-to-mesenchymal transition in pancreatic cancer. World J Surg, 37, 1892-900. DOI ScienceOn |
3 | Yang H, Zhao R, Yang HY, Lee MH (2005). Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity. Oncogene, 24, 1924-35. DOI ScienceOn |
4 | Tang TT, Lasky LA (2003). The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism. J Biol Chem, 278, 30125-35. DOI ScienceOn |
5 | Thiery JP, Acloque H, Huang RY, Nieto MA (2009). Epithelial-mesenchymal transitions in development and disease. Cell, 139, 871-90. DOI ScienceOn |
6 | Tsao S, Liu Y, Wang X, et al (2003). The association of E-cadherin expression and the methylation status of the E-cadherin gene in nasopharyngeal carcinoma cells. Eur J Cancer, 39, 524-31. DOI ScienceOn |
7 | Vaid M, Singh T, Katiyar SK (2011). Grape seed proanthocyanidins inhibit melanoma cell invasiveness by reduction of PGE2 synthesis and reversal of epithelial-to-mesenchymal transition. PLoS One, 6, e21539. DOI |
8 | Wang G, Dong W, Shen H, et al (2011). A comparison of Twist and E-cadherin protein expression in primary non-small-cell lung carcinoma and corresponding metastases. European J Cardio-Thoracic Surg 39, 1028-32. DOI ScienceOn |
9 | Wells A, Yates C, Shepard CR (2008). E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas. Clin Exp Metastasis, 25, 621-8. DOI ScienceOn |
10 | Wen C, Dehnel T (2011). China wrestles with lung cancer. Lancet Oncol, 12, 15. DOI ScienceOn |
11 | Xiang-qiang L, Shan-hong T, Zhi-yong Z, Hai-feng J (2011). [Expression and clinical significance of FOX04 in colorectal cancer]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 27, 969-71. |
12 | McGary EC, Lev DC, Bar-Eli M (2002). Cellular adhesion pathways and metastatic potential of human melanoma. Cancer Biol Ther, 1, 459-65. DOI |
13 | Liu Y (2010). New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol, 21, 212-22. DOI ScienceOn |
14 | Lupertz R, Chovolou Y, Unfried K, et al (2008). The forkhead transcription factor FOXO4 sensitizes cancer cells to doxorubicin-mediated cytotoxicity. Carcinogenesis, 29, 2045-52. DOI ScienceOn |
15 | Obsilova V, Vecer J, Herman P, et al (2005). 14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4. Biochemistry, 44, 11608-17. DOI ScienceOn |
16 | Satelli A, Li S (2011). Vimentin in cancer and its potential as a molecular target for cancer therapy. Cell Mol Life Sci, 68, 3033-46. DOI ScienceOn |
17 | Jemal A, Siegel R, Ward E, et al (2008). Cancer statistics, 2008. CA Cancer J Clin, 58, 71-96. DOI ScienceOn |
18 | Shi X, Wallis AM, Gerard RD, et al (2012). Foxk1 promotes cell proliferation and represses myogenic differentiation by regulating Foxo4 and Mef2. J Cell Sci, 125, 5329-37. DOI |
19 | Silhan J, Vacha P, Strnadova P, et al (2009). 14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4. J Biol Chem, 284, 19349-60. DOI ScienceOn |
20 | Soltermann A, Tischler V, Arbogast S, et al (2008). Prognostic significance of epithelial-mesenchymal and mesenchymal-epithelial transition protein expression in non.small cell lung cancer. Clin Cancer Res, 14, 7430-7. DOI ScienceOn |
21 | Geiger TR, Peeper DS (2009). Metastasis mechanisms. Biochim Biophys Acta-Reviews on Cancer, 1796, 293-308. DOI ScienceOn |
22 | Groome PA, Bolejack V, Crowley JJ, et al (2007). The IASLC Lung Cancer Staging Project: validation of the proposals for revision of the T, N, and M descriptors and consequent stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol, 2, 694-705. DOI |
23 | Ivaska J (2011). Vimentin: Central hub in EMT induction? Small Gtpases, 2, 51-3. DOI |
24 | Joo YE, Rew JS, Choi SK, et al (2002). Expression of E-cadherin and catenins in early gastric cancer. J Clin Gastroenterol, 35, 35-42. DOI ScienceOn |
25 | Joo YE, Rew JS, Park CS, Kim SJ (2002). Expression of E-cadherin, alpha-and beta-catenins in patients with pancreatic adenocarcinoma. Pancreatology, 2, 129-37. DOI ScienceOn |
26 | Liu X, Zhang Z, Sun L, et al (2011). MicroRNA-499-5p promotes cellular invasion and tumor metastasis in colorectal cancer by targeting FOXO4 and PDCD4. Carcinogenesis, 32, 1798-805. DOI ScienceOn |
27 | Kalluri R, Weinberg RA (2009). The basics of epithelial-mesenchymal transition. J Clin Invest, 119, 1420. DOI ScienceOn |
28 | Katoh M (2004). Human FOX gene family (Review). Int J Oncol, 25, 1495-500. |
29 | Kops GJ, de Ruiter ND, De Vries-Smits AM, et al (1999). Direct control of the Forkhead transcription factor AFX by protein kinase B. Nature, 398, 630-4. DOI ScienceOn |
30 | Burgering BM (2008). A brief introduction to FOXOlogy. Oncogene, 27, 2258-62. DOI ScienceOn |
31 | Berx G, Van Roy F (2001). The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression. Breast Cancer Res, 3, 289-93. DOI ScienceOn |
32 | Boura E, Silhan J, Herman P, et al (2007). Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding. J Biol Chem, 282, 8265-75. DOI ScienceOn |
33 | Bremnes RM, Veve R, Hirsch FR, Franklin WA (2002). The E-cadherin cell.cell adhesion complex and lung cancer invasion, metastasis, and prognosis. Lung Cancer, 36, 115-24. DOI ScienceOn |
34 | Calnan DR, Brunet A (2008). The FoxO code. Oncogene, 27, 2276-88. DOI ScienceOn |
35 | Chen L, Tang Y, Wang J, Yan Z, Xu R (2013). miR-421 induces cell proliferation and apoptosis resistance in human nasopharyngeal carcinoma via downregulation of FOXO4. Biochem Biophys Res Commun, 435, 745-50. DOI ScienceOn |
36 | Foroni C, Broggini M, Generali D, Damia G (2012). Epithelial-mesenchymal transition and breast cancer: role, molecular mechanisms and clinical impact. Cancer Treat Rev, 38, 689-97. DOI ScienceOn |
37 | Chuang PY, Yu Q, Fang W, Uribarri J, He JC (2007). Advanced glycation endproducts induce podocyte apoptosis by activation of the FOXO4 transcription factor. Kidney Int, 72, 965-76. DOI ScienceOn |
38 | Dansen TB, Smits LM, van Triest MH, et al (2009). Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity. Nature Chem Biol, 5, 664-72. DOI ScienceOn |
39 | Fan FT, Shen CS, Tao L, et al (2014). PKM2 Regulates hepatocellular carcinoma cell epithelial-mesenchymal transition and migration upon EGFR activation. Asian Pac J Cancer Prev, 15, 1961-70. 과학기술학회마을 DOI ScienceOn |
40 | Awaya H, Takeshima Y, Amatya VJ, et al (2005). Loss of expression of E-cadherin and beta-catenin is associated with progression of pulmonary adenocarcinoma. Pathol Int, 55, 14-8. DOI ScienceOn |
41 | Lee MJ, Yu GR, Yoo HJ, et al (2009). ANXA8 down-regulation by EGF-FOXO4 signaling is involved in cell scattering and tumor metastasis of cholangiocarcinoma. Gastroenterology, 137, 1138-50, 50 e1-9. DOI ScienceOn |
42 | Zhao ZY, Han CG, Liu JT, et al (2013). TIAM2 enhances non-small cell lung cancer cell invasion and motility. Asian Pac J Cancer Prev, 14, 6305-9. 과학기술학회마을 DOI ScienceOn |
43 | Lopez-Novoa JM, Nieto MA (2009). Inflammation and EMT: an alliance towards organ fibrosis and cancer progression. EMBO Mol Med, 1, 303-14. DOI ScienceOn |
44 | Su CY, Li YS, Han Y, Zhou SJ, Liu ZD (2014). Correlation between expression of cell adhesion molecules CD44 v6 and E-cadherin and lymphatic metastasis in non- small cell lung cancer. Asian Pac J Cancer Prev, 15, 2221-4. 과학기술학회마을 DOI ScienceOn |
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