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http://dx.doi.org/10.7314/APJCP.2014.15.3.1419

Esophageal/Gastric Cancer Screening in High-risk Populations in Henan Province, China  

Lu, Yu-Fei (Department of Oncology, Shandong University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute)
Liu, Zhi-Cai (Linzhou Institute of Esophageal Cancer)
Li, Zhong-Hong (Jiyuan cancer hospital)
Ma, Wen-Hao (Huixian People' Hospital)
Wang, Fu-Rang (Department of Tumor Hospital Cancer Prevention Research Office, the Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital)
Zhang, Ya-Bing (Medical Science Research Institute of Henan Province)
Lu, Jian-Bang (Department of Tumor Hospital Cancer Prevention Research Office, the Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.15, no.3, 2014 , pp. 1419-1422 More about this Journal
Abstract
Objective: To summarize the endoscopic screening findings in high-risk population of esophageal and gastric carcinoma and analyze influential factors related to screening. Methods: In seven selected cities and counties with high incidences of esophageal carcinoma, people at age of 40-69 were set as the target population. Those with gastroscopy contradictions were excluded, and all who were voluntary and willing to comply with the medical requirements were subjected to endoscopic screening and histological examination for esophageal, gastric cardia and gastric carcinoma in accordance with national technical manual for early detection and treatment of cancer. Results: In three years, 36,154 people were screened, and 16,847 (46.60%) cases were found to have precancerous lesions. A total of 875 cases were found to have cancers (2.42%), and among them 739 cases had early stage with an early diagnosis rate is 84.5%. Some 715 patients underwent prompt treatment and the success rate was 81.8%. Conclusions: In a high-risk population of esophageal and gastric carcinoma, it is feasible to implement early detection and treatment by endoscopic screening. Screening can identify potential invasive carcinoma, early stage carcinoma and precancerous lesions, improving efficacy through early detection and treatment. The exploratory analysis of related influential factors will help broad implementation of early detection and treatment for esophageal and gastric carcinoma.
Keywords
Esophageal carcinoma; gastric carcinoma; high-risk populations; endoscopy screening; histology;
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1 Wang GQ, Liu YY, Hao CQ, et al (2004). The relationship of esophageal mucosa iodine staining and histological changes of superficial esophageal carcinoma and precancerous lesions. Chin J Cancer, 26, 342-4.
2 Zhao P, Chen WG, Kong LZ (2012). 2003-2007 cancer incidence and mortality in China. Military Medical Science Press, Beijing, China.
3 Zheng RS, Zhang SW, Wu LY, et al (2012). China cancer registry 2008: analysis of incidence and mortality of malignant tumors. ???PLEASE SUPPLY 21, 1-2.
4 Henan research division of cancer prevention (2012). 2011 Annual report of cancer registration. Henan Hospital of Tumor Press, 33-41, Henan, China.
5 Kamangar F, Dores GM, Anderson WF (2006). Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol, 24, 2137-50.   DOI   ScienceOn
6 Lee YY, Oh DK, Choi KS, et al (2011). The current status of gastric cancer screening in Korea: report on the National Cancer Screening Programme, 2009. Asian Pac J Cancer Prev, 12, 3495-500.
7 Lu JB, Liu ZC, Ma WH, et al (2012). Practice and exploration of early diagnosis and treatment in Henan, which is of high incidence of esophageal carcinoma/cardia carcinoma. Chin J Tumor, 21, 828-30.
8 National Cancer Center (2012). China Cancer Registry Annual Report in 2011. Beijing Military Medical Science Press, 194.
9 Jaffer A. Ajani, James S, et al (2011). Esophageal and esophagogastric junction cancers. J Natl Compr Canc Netw, 9, 830-87.
10 National institute of cancer prevention (2008). 2004 Annual Report of cancer registration, Peking Union Medical College Press, Beijing, China.
11 Suh M, Choi KS, Lee YY, et al (2013). Cancer screening in Korea, 2012: results from the Korean national cancer screening survey. Asian Pac J Cancer Prev, 14, 6459-63.   과학기술학회마을   DOI   ScienceOn
12 Wang GQ, Hao CQ, Lai SQ, et al (2003). The application and effect of iodine staining in endoscopic screening in region of high incidence of esophageal carcinoma. Chin J Gastroenterology, 20, 377.
13 Aoki K (2006). Early history of cancer epidemiology and prevention in Japan. Asian Pac J Cancer Prev, 7, 170-6.
14 Dong ZW (2009). Cancer screening and early diagnosis and treatment manual in China (Trial). People's Health Publishing House, 1st Edition.
15 Elliot M. Livstone. Esophageal cancer tumors of the GI tract. Merck Manual, 2012.
16 Ferlay J, Shin HR, Bray F, et al (2010). Estimates of worldwide burden of cancer in 2008: Globocan 2008. Int J Cancer, 127, 2893-917.   DOI   ScienceOn
17 Ministry of Health Bureau of Disease Control and Prevention (2011). Technical proposals for early detection and treatment of cancer (2011 edition), People's Health Publishing House, Beijing, China.