Mechanism of Fatty Acid Synthase in Drug Tolerance Related to Epithelial-mesenchymal Transition of Breast Cancer |
Li, Jun-Qin
(Department of Anatomy, School of Basic and Forensic Medicine, Sichuan University)
Xue, Hui (Department of Anatomy, School of Basic and Forensic Medicine, Sichuan University) Zhou, Lan (Department of Anatomy, School of Basic and Forensic Medicine, Sichuan University) Dong, Li-Hua (Department of Anatomy, School of Basic and Forensic Medicine, Sichuan University) Wei, Da-Peng (Department of Anatomy, School of Basic and Forensic Medicine, Sichuan University) Li, Hua (Department of Anatomy, School of Basic and Forensic Medicine, Sichuan University) |
1 | Hüttemann M, Lee I, LI G, et al (2012). Phosphorylation of mammalian cytochrome c and cytochrome c oxidase in the regulation of cell destiny: respiration, apoptosis, and human disease. Adv Exp Med Biol, 748, 237-64. DOI |
2 | Liu Y, Du F, Chen W, ET AL (2013). Knockdown of dual specificity phosphatase 4 enhances the chemosensitivity of MCF-7 and MCF-7/ADR breast cancer cells to doxorubicin. Exp Cell Res, 319, 3140-9. DOI ScienceOn |
3 |
Kim MK, Maeng YI, Sung WJ, et al (2013). The differential expression of TGF- |
4 | Kim SK, Foote MB, Huang L (2012). The targeted intracellular delivery of cytochrome C protein to tumors using lipidapolipoprotein nanoparticles. Biomaterials, 33, 3959-66. DOI ScienceOn |
5 | Liu H, Liu Y, Zhang JT (2008). A new mechanism of drug resistance in breast cancer cells: fatty acid synthase overexpression-mediated palmitate overproduction. Mol Cancer Ther, 7, 263-70. DOI ScienceOn |
6 | Mani SA, Guo W, Liao MJ, et al (2008). The epithelialmesenchymal transition generates cells with properties of stem cells. Cell, 133, 704-15. DOI ScienceOn |
7 | Meena AS, Sharma A, Kumari R, et al (2013). Inherent and acquired resistance to paclitaxel in hepatocellular carcinoma: molecular events involved. PLoS One, 8, 61524. DOI |
8 | Micalizzi DS, Farabaugh SM, Ford HL (2010). Epithelialmesenchymal transition in cancer: parallels between normal development and tumor progression. J Mammary Gland Biol Neoplasia, 15, 117-34. DOI |
9 | Mihara M, Erster S, Zaika A, et al (2003). p53 has a direct apoptogenic role at the mitochondria. Mol Cell, 11, 577-90. DOI ScienceOn |
10 | Poonyachoti S, Deachapunya C (2012). Modulatory effects of phytoestrogens on the expression of Fas ligand and the release of cytochrome C in normal and cancerous endometrial cells. J Med Assoc Thai, 12, 105-12. |
11 |
Tian X, Liu Z, Niu B, et al (2011). E-cadherin/ |
12 | Puig T, Aguilar H, Cufi S, et al (2011). A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines. Breast Cancer Res, 13, 131. DOI |
13 |
Ramirez Alvarado M, Sanchez Roitz C (2012). El factor de necrosis tumoral- |
14 | Sethi JK, Xu H, Uysal KT, et al (2000). Characterisation of receptor-specific TNFalpha functions in adipocytecell lines lacking type 1 and 2 TNF receptors. FEBS Lett, 469, 77-82. DOI ScienceOn |
15 | Urruticoechea A, Aguilar H, Cufi S, et al (2009). In vivo and in vitro evidence of antitumor activity of UCM-GI028 against trastuzumab-resistant breast cancer. Cancer Res, 69, 5079. |
16 | Wang Y, Tian WX, Ma XF. (2013). Inhibitory effects of onion (Allium cepa L.) extract on proliferation of cancer cells and adipocytes via inhibiting fatty acid synthase. Asian Pac J Cancer Prev, 13, 5573-9. 과학기술학회마을 DOI ScienceOn |
17 | Wang ZW, Li YW, Kong DJ, et al (2009). Acquisition of Epithelial-Mesenchymal Transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of Notch signaling pathway. Cancer Res, 69, 2400-7. DOI ScienceOn |
18 | Zhao B, Li L, Cui K, et al (2011). Mechanisms of TRAIL and gemcitabine induction of pancreatic cancer cell apoptosis. Asian Pac J Cancer Prev, 12, 2675-8. |
19 |
Xiao Y, Li H, Zhang J, et al (2011). TNF- |
20 |
Xu TP, Shen H, Liu LX, Shu YQ (2013). Plumbagin from Plumbago zeylanica L induces apoptosis in human non-small cell lung cancer cell lines through NF- |
21 |
Zhou CH, Nitschke AM, Xiong W, et al (2008). Proteomic analysis of tumor necrosis factor- |
22 | Foster SS, De S, Johnson LK, et al (2012). Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression. Proc Natl Acad Sci USA, 109, 9953-8. DOI |
23 | Chen S, Denis CG, You ZB, et al (2001). Wnt-1 Signaling inhibits apoptosis by activating b-catenin/T cell factor-mediated transcription. J Cell Biol, 152, 87-96. DOI ScienceOn |
24 | Chopra M, Riedel SS, Biehl M, et al (2013). Tumor necrosis factor receptor 2-dependent homeostasis of regulatory T cells as a player in TNF-induced experimental metastasis. Carcinogenesis, 34, 1296-303. DOI ScienceOn |
25 | Gao FL, Song WG, Li WS, et al (2012). Correlation between expression of apoptosis modulators Smac and Cyt C and prognosis in esophageal squamous cell carcinoma. World Chinese J Digestology, 29, 226-8. |
26 | Espinoza I, Hong PC, Busby R, Ruth L (2010). Inhibition of fatty acid synthase (FASN) sensitizes breast cancer cells to chemotherapy and disrupts the lipid rafts. Cancer Res, 70, p4-03-01. DOI |
27 | Fiorentino M, Zadra G, Palescandolo E, et al (2008). Overexpression of fatty acid synthase is associated with palmitoylation of Wnt-11 and cytoplasmic stabilization of b-catenin in prostate cancer. Lab Invest, 88, 1340-8. DOI ScienceOn |
28 | Han RF, Ji X, Dong XG, et al (2013). An epigenetic mechanism underlying doxorubicin induced EMT in the human BGC-823 gastric cancer cell. Asian Pac J Cancer Prev, 15, 4271-4. 과학기술학회마을 DOI ScienceOn |
29 | Han XY, Wei B, Fang JF, et al (2013). Epithelial-mesenchymal transition associates with maintenance of stemness in spheroid-derived stem-like colon cancer cells. PLoS One, 8, 73341. DOI |
30 | Heinlein C, Krepulat F, Lohler J, et al (2008). Mutant p53 (R270H) gain of function phenotype in a mouse model for oncogene-induced mammary carcinogenesis. Int J Cancer, 122, 1701-9. |
31 | Hung CM, Kuo DH, Chou CH, et al (2011). Osthole suppresses hepatocyte growth factor (HGF)-induced epithelialmesenchymal transition via repression of the c-Met/Akt/mTOR pathway in human breast cancer cells. J Agric Food Chem, 5, 9683-90. |
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