MicroRNAs: Biogenesis, Roles for Carcinogenesis and as Potential Biomarkers for Cancer Diagnosis and Prognosis |
Kavitha, Nowroji
(Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia)
Vijayarathna, Soundararajan (Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia) Jothy, Subramanion Lachumy (Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia) Oon, Chern Ein (Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia) Chen, Yeng (Dental Research & Training Unit, and Oral Cancer Research and Coordinating Centre (OCRCC), Faculty of Dentistry, University of Malaya) Kanwar, Jagat Rakesh (Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR), School of Medicine (SoM), Molecular and Medical Research (MMR) Strategic Research Centre, Faculty of Health, Deakin University) Sasidharan, Sreenivasan (Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia) |
1 | Bueno MJ, Malumbres M (2011). MicroRNAs and the cell cycle. Biochim Biophys Acta, 1812, 592-601. DOI |
2 | Chang CJ, Chao CH, Xia W, et al (2011). p53 regulates epithelialmesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol, 13, 317-23. DOI |
3 | Calin GA, Cimmino A, Fabbri M, et al (2008). MiR-15a and miR-16-1 cluster functions in human leukemia. Proc Natl Acad Sci USA, 105, 5166-71. DOI |
4 | Calin GA, Croce CM (2006). MicroRNA signatures in human cancers. Nat Rev Cancer, 6, 857-66. DOI ScienceOn |
5 | Carthew RW, Sontheimer EJ (2009). Origins and mechanisms of miRNAs and siRNAs. Cell, 136, 642-55. DOI ScienceOn |
6 | Corsini LR, Bronte G, Terrasi M, et al (2012). The role of microRNAs in cancer: diagnostic and prognostic biomarkers and targets of therapies. Expert Opin Ther Tar, 16, 103-9. DOI |
7 | Cortez MA, Welsh JW, Calin GA (2012). Circulating microRNAs as noninvasive biomarkers in breast cancer. Rec Res Cancer Res, 195, 151-61. DOI |
8 | Croce CM (2013). Ultraconserved regions encoding ncRNAs. US Patent App. 2013, 13/910,410. |
9 | Croce CM, Liu CG, Calin GA, Sevignani C (2010). Diagnosis and treatment of cancers with microRNA located in or near cancer associated chromosomal features. Patents, US20100234241 A1. |
10 | Croce CM: Causes and consequences of microRNA dysregulation in cancer (2009). Nat Rev Genetics, 10, 704-14. DOI ScienceOn |
11 | Deng G, Sui G (2013). Noncoding RNA in oncogenesis: a new era of identifying key players. Int J Mol Sci, 14, 18319-49. DOI |
12 | Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R (2005). Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell, 123, 631-40. DOI ScienceOn |
13 | Griffiths-Jones S, Saini HK, Van Dongen S, Enright AJ (2008). miRBase: tools for microRNA genomics. Nucleic Acids Res, 36, 154-8. DOI ScienceOn |
14 | Han J, Pedersen JS, Kwon SC, et al (2009). Posttranscriptional crossregulation between Drosha and DGCR8. Cell, 136, 75-84. DOI ScienceOn |
15 | Hu Z, Chen X, Zhao Y, et al (2010). Serum MicroRNA signatures identified in a genome-wide serum MicroRNA expression profiling predict survival of non-small-cell lung cancer. J Clin Oncol, 28, 1721-6. DOI ScienceOn |
16 | Hanke M, Hoefig K, Merz H, et al (2010). A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer. In: Urologic Oncology: Seminars and Original Investigations, 11, 655-61. |
17 | He L, He X, Lowe SW, Hannon GJ (2007). microRNAs join the p53 network-another piece in the tumour-suppression puzzle. Nat Rev Cancer, 7, 819-22. DOI ScienceOn |
18 | Heneghan HM, Miller N, Kerin MJ (2010). MiRNAs as biomarkers and therapeutic targets in cancer. Curr Opin Pharmacol, 10, 543-50. DOI ScienceOn |
19 | Iliopoulos D, Lindahl-Allen M, Polytarchou C, et al (2010). Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Mol Cell, 39, 761-72. DOI |
20 | Inui M, Martello G, Piccolo S (2010). MicroRNA control of signal transduction. Nat Rev Mol Cell Biol, 11, 252-63. DOI ScienceOn |
21 | Melo SA, Moutinho C, Ropero S, et al (2010). A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. Cancer cell, 18, 303-15. DOI |
22 | Lujambio A, Lowe SW (2012). The microcosmos of cancer. Nature, 482, 347-55. DOI |
23 | Malumbres M, Barbacid M (2001). Milestones in cell division: to cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer, 1, 222-31. DOI |
24 | Martinez NJ, Gregory RI (2013). Argonaute2 expression is post-transcriptionally coupled to microRNA abundance. RNA, 19, 605-12. DOI |
25 | Mcbride O, Merry D, Givol D (1986). The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13). Proc Natl Acad Sci U.S.A, 83, 130-4. DOI ScienceOn |
26 | Melo SA, Esteller M (2011). A precursor microRNA in a cancer cell nucleus: get me out of here! Cell Cycle, 10, 922-5. DOI |
27 | Melo SA, Esteller M (2011). Dysregulation of microRNAs in cancer: playing with fire. FEBS Letters, 585, 2087-99. DOI |
28 | Melo SA, Ropero S, Moutinho C, et al (2009). A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat Genetics, 41, 365-70. DOI |
29 | Meng F, Henson R, Wehbe-Janek H, et al (2007). MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology, 133, 647-58. DOI ScienceOn |
30 | Mitchell PS, Tewari M (2010). Circulating microRNAs in cancer. In Kikuchi Y. and Rykova EY. (Eds.), Nucleic acids and molecular biology series: extracellular nucleic acids, Springer, 129-46. |
31 | Khan N, Cheng J, Pezacki JP, Berezovski MV (2011). Quantitative analysis of microRNA in blood serum with protein-facilitated affinity capillary electrophoresis. Anal Chem, 83, 6196-01. DOI |
32 | Iorio MV, Croce CM (2012). MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol Med, 4, 143-59. DOI |
33 | Iorio MV, Croce CM (2012). microRNA involvement in human cancer. Carcinogenesis, 33, 1126-33. DOI |
34 | Iorio MV, Ferracin M, Liu CG, et al (2005). MicroRNA gene expression deregulation in human breast cancer. Cancer Res, 65, 7065-70. DOI ScienceOn |
35 | Jansson MD, Lund AH (2012). MicroRNA and cancer. Mol Oncol, 6, 590-610. DOI |
36 | Josephine WD, Cui M, Shibata R, Cheng L, Zhang DY (2013). Diagnostic methodology and technology. In Molecular Genetic Pathology, Cheng, Liang, Zhang, David Y., Eble, John N. (Eds.), Springer, 2nd ed., XXI, 1136 p. |
37 | Karreth FA, Tay Y, Perna D, et al (2011). In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAFinduced mouse model of melanoma. Cell, 147, 382-95. DOI |
38 | Kim VN, Han J, Siomi MC (2009). Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol, 10, 126-39. DOI ScienceOn |
39 | Kobayashi E, Hornicek FJ, Duan Z (2012). MicroRNA involvement in osteosarcoma. Clin Sarcoma Res, 12, 359-739. |
40 | Kong YW, Ferland-Mccollough D, Jackson TJ, Bushell M (2012). microRNAs in cancer management. The Lancet Oncol, 13, 249-258. DOI ScienceOn |
41 | Krell J, Frampton AE, Colombo T, et al (2013). The p53 miRNA interactome and its potential role in the cancer clinic. Epigenomics, 5, 417-28. DOI |
42 | Ofir M, Hacohen D, Ginsberg D (2011). MiR-15 and miR-16 are direct transcriptional targets of E2F1 that limit E2F-induced proliferation by targeting cyclin E. Mol Cancer Res, 9, 440-7. DOI |
43 | Mollaie HR, Monavari SH, Arabzadeh SA, et al (2013). RNAi and miRNA in viral infections and cancers. Asian Pac J Cancer Prev, 14, 7045-56. DOI ScienceOn |
44 | Nana-Sinkam SP, Croce CM (2011). MicroRNAs as therapeutic targets in cancer. Transl Res, 157, 216-25. DOI ScienceOn |
45 | Nishida N, Mimori K, Mori M, Calin GA (2013). EGFR gets in the way of microRNA biogenesis. Cell Research, 23, 1157-8. DOI |
46 | Ramshankar V, Krishnamurthy A (2013). Lung cancer detection by screening - presenting circulating miRNAs as a promising next generation biomarker breakthrough. Asian Pac J Cancer Prev, 14, 2167-72. 과학기술학회마을 DOI ScienceOn |
47 | Orang AV, Safaralizadeh R, Hosseinpour Feizi MA (2014). Insights into the diverse roles of miR-205 in human cancers. Asian Pac J Cancer Prev, 15, 577-583. DOI ScienceOn |
48 | Parasramka MA, Ho E, Williams DE, Dashwood RH (2012). MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals. Mol Carcinogen, 51, 213-30. DOI |
49 |
Petrocca F, Visone R, Onelli MR, et al (2008). E2F1-regulated microRNAs impair TGF |
50 | Ruby JG, Jan CH, Bartel DP (2007). Intronic microRNA precursors that bypass Drosha processing. Nature, 448, 83-6. DOI ScienceOn |
51 | Shen J, Xia W, Khotskaya YB, et al (2013). EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature, 497, 383-7. DOI |
52 | Saito Y, Liang G, Egger G, et al (2006). Specific activation of microRNA-127 with downregulation of the proto-oncogene by chromatin-modifying drugs in human cancer cells. Cancer Cell, 9, 435-43. DOI ScienceOn |
53 | Salmena L, Poliseno L, Tay Y, Kats L, Pandolfi PP (2011). A ceRNA hypothesis: the rosetta stone of a hidden RNA language? Cell, 146, 353-8. DOI ScienceOn |
54 | Sanchez-Diaz PC, Hsiao TH, Chang JC, et al (2013). Deregulated microRNAs in pediatric cancer stem cells target pathways involved in cell proliferation, cell cycle and development. PloS One, 8, 61622. DOI |
55 | Su X, Chakravarti D, Cho MS, et al (2010). TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature, 467, 986-90. DOI ScienceOn |
56 | Streichert T, Otto B, Lehmann U (2011). MicroRNA profiling using fluorescence-labeled beads: data acquisition and processing. Methods Mol Biol, 676, 253-68. DOI |
57 | Streichert T, Otto B, Lehmann U (2012). microRNA expression profiling in archival tissue specimens: methods and data processing. Mol Biotechnol, 50, 159-69. DOI |
58 | Su X, Xing J, Wang Z, et al (2013). microRNAs and ceRNAs:RNA networks in pathogenesis of cancer. Chin J Cancer Res, 25, 235-9. |
59 | Suzuki HI, Yamagata K, Sugimoto K, et al (2009). Modulation of microRNA processing by p53. Nature, 460, 529-33. DOI ScienceOn |
60 | Taby R, Issa JPJ (2010). Cancer epigenetics. CA Cancer J Clin, 60, 376-92. DOI |
61 | Vasudevan S, Tong Y, Steitz JA (2007). Switching from repression to activation: microRNAs can up-regulate translation. Science, 318, 1931-4. DOI ScienceOn |
62 | Toyota M, Suzuki H, Sasaki Y, et al (2008). Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res, 68, 4123-32. DOI ScienceOn |
63 | Van Kouwenhove M, Kedde M, Agami R (2011). MicroRNA regulation by RNA-binding proteins and its implications for cancer. Nat Rev Cancer, 11, 644-56. DOI ScienceOn |
64 | Varambally S, Cao Q, Mani RS, et al (2008). Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science, 322, 1695-9. DOI ScienceOn |
65 | Volinia S, Calin GA, Liu CG, et al (2006). A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA, 103, 2257-61. DOI ScienceOn |
66 | Volinia S, Galasso M, Sana ME, et al (2012). Breast cancer signatures for invasiveness and prognosis defined by deep sequencing of microRNA. Proc Natl Acad Sci USA, 109, 3024-9. DOI |
67 | Wan SM, Lv F, Guan T (2012). Identification of genes and microRNAs involved in ovarian carcinogenesis. Asian Pac J Cancer Prev, 13, 3997-4000. DOI ScienceOn |
68 | Wong KY, Yu L, Chim CS (2011). DNA methylation of tumor suppressor miRNA genes: a lesson from the miR-34 family. Epigenomics, 3, 83-92. DOI |
69 | Wynendaele J, Bohnke A, Leucci E, et al (2010). An illegitimate microRNA target site within the 3'UTR of MDM4 affects ovarian cancer progression and chemosensitivity. Cancer Res, 70, 9641-9. DOI |
70 | Xu L, Dai WQ, Xu XF, et al (2012). Effects of multiple-target anti-microRNA antisense oligodeoxyribonucleotides on proliferation and migration ofgastric cancer cells. Asian Pac J Cancer Prev, 13, 3203-7. DOI ScienceOn |
71 | Zenz T, Mohr J, Eldering E, et al (2009). miR-34a as part of the resistance network in chronic lymphocytic leukemia. Blood, 113, 3801-8. DOI ScienceOn |
72 | Zhao SF, Zhang X, Zhang XJ, et al (2014). Induction of MicroRNA-9 mediates cytotoxicity of curcumin against SKOV3 ovarian cancer cells. Asian Pac J Cancer Prev, 15, 3363-8. 과학기술학회마을 DOI |
73 | Bhayani MK, Calin GA, Lai SY (2012). Functional relevance of miRNA* sequences in human disease. Mutat Res-Fund Mol M, 731, 14-9. DOI |
74 | Bartel DP (2009). MicroRNAs: target recognition and regulatory functions. Cell, 136, 215-33. DOI ScienceOn |
75 | Beitzinger M, Meister G (2010). MicroRNAs: from decay to decoy. Cell, 140, 612-14. DOI |
76 | Berezikov E, Guryev V, Van De Belt J, et al (2005). Phylogenetic shadowing and computational identification of human microRNA genes. Cell, 120, 21-4. DOI ScienceOn |
77 | Farooqi AA, Qureshi MZ, Coskunpinar E, et al (2014). miR-421, miR-155 and miR-650: Emerging trends of regulation of cancer and apoptosis. Asian Pac J Cancer Prev, 15, 1909-12. 과학기술학회마을 DOI ScienceOn |
78 | Duan W, Gao L, Wu X, et al (2010). MicroRNA-34a is an important component of PRIMA-1-induced apoptotic network in human lung cancer cells. Int J Cancer, 127, 313-20. |
79 | Fornari F, Gramantieri L, Ferracin M, et al (2008). MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma. Oncogene, 27, 5651-61. DOI ScienceOn |
80 | Farazi TA, Hoell JI, Morozov P, Tuschl T (2013). MicroRNAs in human cancer. Adv Exp Med Biol, 774, 1-20. DOI ScienceOn |
81 | Fink SP, Kishore Guda D(2013) Application of next-generation sequencing in RNA biomarker discovery in cancer research, In next generation sequencing in cancer research, Wu, Wei, Choudhry, Hani (Eds.), Springer, 1, 383. |
82 | Frankel LB, Christoffersen NR, Jacobsen A, et al (2008). Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Bio Chem, 283, 1026-33. DOI ScienceOn |
83 | Garzon R, Heaphy CE, Havelange V, et al (2009). MicroRNA 29b functions in acute myeloid leukemia. Blood, 114, 5331-41. DOI ScienceOn |
84 | Garzon R, Marcucci G, Croce CM (2010). Targeting microRNAs in cancer: rationale, strategies and challenges. Nat Rev Drug Discovery, 9, 775-89. DOI ScienceOn |
85 | Ghildiyal M, Zamore PD (2009). Small silencing RNAs: an expanding universe. Nat Rev Genet, 10, 94-108. DOI ScienceOn |
86 | Lin C, Huang F, Zhang Y, Tuokan T, Kuerban G. (2014). Roles of MiR-101 and its target gene cox-2 in early diagnosis of cervical cancer in Uygur women. Asian Pac J Cancer Prev, 15, 45-8. DOI ScienceOn |
87 | Krol J, Loedige I, Filipowicz W (2010). The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet, 11, 597-610. |
88 | Kumar MS, Pester RE, Chen CY, et al (2009). Dicer1 functions as a haploinsufficient tumor suppressor. Genes Dev, 23, 2700-4. DOI |
89 | Lawrie CH (2008). MicroRNA expression in lymphoid malignancies: new hope for diagnosis and therapy? J Cell Mol Med, 12, 1432-44. DOI |
90 | Lhakhang TW, Chaudhry M (2012). Current approaches to micro-RNA analysis and target gene prediction. J App Gene, 53, 149-58. DOI |
91 | Lim LP, Lau NC, Garrett-Engele P, et al (2005). Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature, 433, 769-73. DOI ScienceOn |
92 | Link A, Balaguer F, Shen Y, et al (2010). MicroRNAs as novel biomarkers for colon cancer screening. Cancer Epidem Biomar Prev, 19, 1766-74. DOI ScienceOn |
93 | Liu R, Zhang C, Hu Z, et al (2011). A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis. Eur J Cancer, 47, 784-91. DOI ScienceOn |
94 | Lopez-Serra P, Esteller M (2011). DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer. Oncogene, 31, 1609-22. |
95 | Lujambio A, Calin GA, Villanueva A, et al (2008). A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci USA, 105, 13556-61. DOI |
96 | Lee RC, Feinbaum, RL, d Ambros V (1993). The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 75, 843-54. DOI ScienceOn |
97 | Baumhoer D, Zillmer S, Unger K, et al (2012). MicroRNA profiling with correlation to gene expression revealed the oncogenic miR-17-92 cluster to be up-regulated in osteosarcoma. Cancer Genet, 205, 212-19. DOI |
98 | Fabbri M, Garzon R, Cimmino A, et al (2007). MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci USA, 104, 15805-10. DOI ScienceOn |
99 | Iorio MV, Casalini P, Piovan C, Braccioli L, Tagliabue E (2012). Current and future developments in cancer therapy research: mirnas as new promising targets or tools. In Biotargets of Cancer in Current Clinical Practice, Bologna, M. (Ed.), Springer. XVI, 563. |
100 | Reinhart BJ, Slack FJ, Basson M, et al (2000). The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature, 403, 901-6. DOI ScienceOn |
101 | Stenvang J, Silahtaroglu AN, Lindow M, Elmen J, Kauppinen S (2008). The utility of LNA in microRNA-based cancer diagnostics and therapeutics. Semin Cancer Biol, 18, 89-102. DOI |
![]() |