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http://dx.doi.org/10.7314/APJCP.2014.15.13.5167

Characteristics of Hodgkin Lymphoma in a Defined Group of Iranian Pediatric Patients  

Baharvand, Maryam (Department of Oral Medicine, Faculty of Dentistry, Shahid Beheshti University of Medical Sciences)
Mortazavi, Hamed (Department of Oral Medicine, Faculty of Dentistry, Shahid Beheshti University of Medical Sciences)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.15, no.13, 2014 , pp. 5167-5169 More about this Journal
Abstract
This study was conducted to describe the characteristics of Hodgkin lymphoma in Iranian children. In a referral center for pediatric oncology (Mofid Hospital) in Tehran, patient data over a 10-year period were retrieved and recorded accordingly. Among 82 cases, 73.2% were male, 26.8% were female, and 70.7% were 5-9 years old. About 40% of patients were in stage III and 42.7% had systemic signs. Cervical nodes were commonly involved (91.5%). The most frequent histological subtype was mixed cellularity. The main hematological features were anemia (47.6%), lymphopenia (20.7%), and eosinophilia (8.7%). Survival rate was 72%, and 8.4% of patients were deceased. A 3% recurrence rate was observed in our patients. A significant relationship was found between the stage of disease and systemic signs (P<0.0005, ${\chi}^2$). Despite diagnosis of Hodgkin lymphoma in many children in Iran being made in higher stages, the mortality rate is relatively low.
Keywords
Hodgkin lymphoma; pediatric; Iran;
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