Parthenolide-Induced Apoptosis, Autophagy and Suppression of Proliferation in HepG2 Cells |
Sun, Jing
(National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University)
Zhang, Chan (National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University) Bao, Yong-Li (National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University) Wu, Yin (National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University) Chen, Zhong-Liang (Research Center of Agriculture and Medicine Gene Engineering of Ministry of Education) Yu, Chun-Lei (National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University) Huang, Yan-Xin (National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University) Sun, Ying (Research Center of Agriculture and Medicine Gene Engineering of Ministry of Education) Zheng, Li-Hua (National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University) Wang, Xue (China-Japan Union Hospital of Jilin University) Li, Yu-Xin (Research Center of Agriculture and Medicine Gene Engineering of Ministry of Education) |
1 | Zhang S, Ong CN, Shen HM (2004). Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells. Cancer Lett, 208, 143-53. DOI ScienceOn |
2 | Signore M, Ricci-Vitiani L, De Maria R (2012). Targeting apoptosis pathways in cancer stem cells. Cancer Lett, 332, 374-82. |
3 | Sobota R, Szwed M, Kasza A, et al (2000). Parthenolide inhibits activation of signal transducers and activators of transcription (STATs) induced by cytokines of the IL-6 family. Biochem Biophys Res Commun, 267, 329-33. DOI ScienceOn |
4 | Wang X (2001). The expanding role of mitochondria in apoptosis. Genes, 15, 2922-33. |
5 | Zhang S, Ong CN, Shen HM (2004). Involvement of proapoptotic bcl-2 family members in parthenolide-induced mitochondrial dysfunction and apoptosis. Cancer Lett, 211, 175-88. DOI ScienceOn |
6 | Zhang Y, Chen AY, Li M, Chen C, et al (2008). Ginkgo biloba extract kaempferol inhibits cell proliferation and induces apoptosis in pancreatic cancer cells. J Surg Res, 148, 17-23. DOI ScienceOn |
7 | Zunino SJ, Ducore JM, Storms DH (2007). Parthenolide induces significant apoptosis and production of reactive oxygen species in high-risk pre-B leukemia cells. Cancer Lett, 254, 119-27. DOI ScienceOn |
8 | Newman DJ (2008). Natural products as leads to potential drugs: an old process or the new hope for drug discovery. J Med Chem, 51, 2589-99. DOI ScienceOn |
9 | Mains RE, May V (1988). The role of a low pH intracellular compartment in the processing, storage, and secretion of ACTH and endorphin. J Biol Chem, 263, 7887-94. |
10 | Mathema VB, Koh YS, Thakuri BC, et al (2012). Parthenolide, a sesquiterpene lactone, expresses multiple anti-cancer and anti-inflammatory activities. Inflammation, 35, 560-5. DOI ScienceOn |
11 | Mizushima N (2004). Methods for monitoring autophagy. Int J Biochem Cell B, 36, 2491-502. DOI ScienceOn |
12 | Obiol-Pardo C, Granadino-Roldan JM, Rubio-Martinez J (2008). Protein-protein recognition as a first step towards the inhibition of XIAP and Survivin anti-apoptotic proteins. J Mol Recognit, 21, 190-204. DOI ScienceOn |
13 | Overholtzer M, Mailleux AA, Mouneimne G, et al (2007). A nonapop-totic cell death process, entosis, that occurs by cell-in-cell invasion. Cell, 131, 966-79. DOI ScienceOn |
14 | Paglin S, Hollister T, Delohery T, et al (2001). A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Res, 61, 439-44. |
15 | Parada-Turska J, Paduch R, Majdan M, et al (2007). Antiproliferative activity of parthenolide against three human cancer cell lines and human umbilical vein endothelial cells. Pharmacol Rep, 59, 233-7. |
16 | Riedl SJ, Shi Y (2004). Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol, 5, 897-907. DOI ScienceOn |
17 | Gomaa AI, Khan SA, Toledano MB, et al (2008). Hepatocellular carcinoma: epidemiology, risk factors and pathogenesis. World J Gastroenterol, 14, 4300-8. DOI ScienceOn |
18 | Shu KX, Li B, Wu LX (2007). The p53 network: p53 and its downstream genes. Colloids Surf B, 55, 10-8. DOI ScienceOn |
19 | Green DR, Evan GI (2002). A matter of life and death. Cancer Cell, 1, 19-30. DOI ScienceOn |
20 | Gerdes J, Lemke H, Baisch H, et al (1984). Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol, 133, 1710-5. |
21 | Kaseb AO, Abaza YM, Roses RE (2013). Multidisciplinary management of hepatocellular carcinoma. Recent Results Cancer Res, 190, 247-59. DOI |
22 | Leong S, McKay MJ, Christopherson RI, et al (2012). Biomarkers of breast cancer apoptosis induced by chemotherapy and TRAIL. J Proteome Res, 11, 1240-50. DOI ScienceOn |
23 | Knight DW (1995). Feverfew, chemistry and biological activity. Nat Prod Rep, 12, 271-6. DOI ScienceOn |
24 | Kondo Y, Kanzawa T, Sawaya R, et al (2005). The role of autophagy in cancer development and response to therapy. Nat Rev Cancer, 5, 726-34. DOI ScienceOn |
25 | Kwok BH, Koh B, Ndubuisi MI, et al (2001). The antiinflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase. Chem Biol, 8, 759-66. DOI ScienceOn |
26 | Levine B, Kroemer G (2008). Autophagy in the pathogenesis of disease. Cell, 132, 27-42. DOI ScienceOn |
27 | Lizuka N, Miyamoto K, Okita K, et al (2000). Inhibitory effect of Coptidis Rhizoma and berberine on the proliferation of human esophageal cancer cell lines. Cancer Lett, 148, 19-25. DOI ScienceOn |
28 | Lockshin RA, Zakeri Z (2004). Caspase-independent cell death. Oncogene, 23, 2766. DOI ScienceOn |
29 | Avila MA, Berasain C, Sangro B, et al (2006). New therapies for hepatocellular carcinoma. Oncogene, 25, 3866-84. DOI ScienceOn |
30 | Biederbick A, Kern HF, Elsasser HP (1995). Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. Eur J Cell Biol, 6, 3-14. |
31 | Cui J, Gong Z, Shen HM (2013). The role of autophagy in liver cancer: molecular mechanisms and potential therapeutic targets. Biochim Biophys Acta, 1836, 15-26. |
32 | DU P, Cao H, Wu HR (2013). Blocking Bcl-2 Leads to autophagy activation and cell death of the HEPG2 liver cancer cell line. Asian Pac J Cancer Prev, 14, 5849-54. 과학기술학회마을 DOI ScienceOn |
33 | Rocha AB, Lopes RM, Schwartsmann G (2001). Natural products in anticancer therapy. Curr Opin Pharmacol, 1, 364-9. DOI ScienceOn |
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