Browse > Article
http://dx.doi.org/10.7314/APJCP.2014.15.12.4847

Oncoplastic Breast Conserving Surgery with Nipple-areolar Preservation for Centrally Located Breast Cancer: a Retrospective Cohort Study  

Ren, Zhao-Jun (Department of Pathology, Jiangsu Cancer Hospital)
Li, Xiu-Juan (Department of General Surgery, Jiangsu Cancer Hospital)
Xu, Xin-Yu (Department of Pathology, Jiangsu Cancer Hospital)
Xia, Lei (Department of Pathology, Jiangsu Cancer Hospital)
Tang, Jin-Hai (Department of General Surgery, Jiangsu Cancer Hospital)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.15, no.12, 2014 , pp. 4847-4849 More about this Journal
Abstract
A compariosn was made of survival outcomes of oncoplastic breast conserving therapy (oBCT) with nipple-areolar (NAC) preservation in women with centrally located breast cancer (CLBC) undergoing modified radical mastectomy (MRM) in China in a matched retrospective cohort study. We used a database including patients who received oBCT (n=91) or MRM (n=182) from 2003 to 2013 in our hospital. Matching was conducted according to five variables: age at diagnosis, axillary lymph node status, hormone receptor status, human epidermal growth factor-like receptor 2 status (HER-2) and tumor stage. The match ratio was 1:2. Median follow-up times for the oBCT and MRM groups were 83 and 81 months, respectively. There were no significant differences in 87-month overall, local, or distant recurrence-free survival between patients with oBCT and MRM (89%vs.90%; 93%vs.95%; 91%vs.92%;). For appropriate breast cancer patients, oBCT for CLBC is oncologically safe, oncoplastic techniques improving cosmetic outcomes.
Keywords
Oncoplastic breast conserving surgery; nipple-areolar preservation; centrally located breast cancer;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Veronesi U, Cascinelli N, Mariani L, et al (2002). Twentyyear follow-up of a randomized study comparing breastconserving surgery with radical mastectomy for early breast cancer. N Engl J Med, 347, 1227-32.   DOI   ScienceOn
2 Spear SL, Pelletiere CV, Wolfe AJ, et al (2003). Experience with reduction mammaplasty combined with breast conservation therapy in the treatment of breast cancer. Plast Reconstr Surg, 111, 1102-9.   DOI   ScienceOn
3 Sun Meng-Qing. Meng Ai-Feng. Huang Xin-En. Wang Mei-Xiang (2013). Comparison of psychological influence on breast cancer patients between breast-conserving surgery and modified radical mastectomy. Asian Pac J Cancer Prev, 14, 149-52.   과학기술학회마을   DOI   ScienceOn
4 Gerber B, Krause A, Reimer T, et al (2003). Skin-sparing mastectomy with conservation of the nipple-areola complex and autologous reconstruction is an oncologically safe procedure. Ann Surg, 238, 120-7.
5 Dale PS, Giuliano AE (1996). Nipple-areolar preservation duringbreast-conserving therapy for subareolar breast carcinomas. Arch Surg, 131, 430-3.   DOI
6 Fisher B, Anderson S, Bryant J, et al (2002). Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med, 3471, 233-41.
7 Fitzal F, Mittlboeck M, Trischler H, et al (2008). Breastconserving therapy for centrally located breast cancer. Ann Surg, 247, 470-6.   DOI   ScienceOn
8 Parry RG, Cochran TC, Wolfort FG (1977). When is there nipple involvement in carcinoma of the breast? Plast Reconstr Surg, 59, 535-7.   DOI   ScienceOn
9 Poggi MM, Danforth DN, Sciuto LC, et al (2003). Eighteenyear results in the treatment of early breast carcinoma with mastectomy versus breast conservation therapy: the National Cancer Institute Randomized Trial. Cancer, 98, 697-702.   DOI   ScienceOn
10 Rusby JE, Brachtel EF, Othus M, et al (2008). Development and validation of a model predictive of occult nipple involvement in women undergoing mastectomy. Br J Surg, 95, 1356-61.   DOI   ScienceOn
11 Simmons RM, Brennan MB, Christos P, Sckolnick M, Osborne M (2001). Recurrence rates in patients with central or retroareolar breast cancers treated with mastectomy or lumpectomy. Am J Surg, 182, 325-9.   DOI   ScienceOn
12 Arriagada R, Le MG, Guinebretiere JM, et al (2003). Late local recurrences in a randomised trial comparing conservative treatment with total mastectomy in early breast cancer patients. Ann Oncol, 14, 1617-22.   DOI   ScienceOn
13 Jia WJ, Jia HX, Feng HY, et al (2014). HER2-enriched tumors have the highest risk of local recurrence in Chinese patients treated with breast conservation therapy. Asian Pac J Cancer Prev, 15, 315-20.   과학기술학회마을   DOI   ScienceOn
14 Blichert-Toft M, Nielsen M, During M, et al (2008). Long-term results of breast conserving surgery vs. mastectomy for early stage invasive breast cancer: 20-year follow-up of the Danish randomized dbcg-82TM protocol. Acta Oncol, 47, 672-81.   DOI   ScienceOn
15 Brachtel EF, Rusby JE, Michaelson JS, et al (2009). Occult nipple involvement in breast cancer: clinicopathologic findings in 316 consecutive mastectomy specimens. J Clin Oncol, 27, 4948-54.   DOI   ScienceOn
16 Van Dongen JA, Voogd AC, Fentiman IS, et al (2000). Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for Research and Treatment of Cancer 10801 trial. J Natl Cancer Inst, 92, 1143-50.   DOI   ScienceOn