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http://dx.doi.org/10.7314/APJCP.2013.14.8.4913

Inpatients' Knowledge about Primary Liver Cancer and Hepatitis  

He, Wen-Jing (Shantou University of Medical College, Shantou University Medical College)
Xu, Ming-Yan (Laboratory of Cell Senescence, Shantou University Medical College)
Xu, Rui-Rui (Department of Minimally Invasive Surgery, Second Affiliated Hospital of Shantou University Medical College)
Zhou, Xiao-Qiong (Shantou University of Medical College, Shantou University Medical College)
Ouyang, Jun-Jie (Shantou University of Medical College, Shantou University Medical College)
Han, Hui (Department of Minimally Invasive Surgery, Second Affiliated Hospital of Shantou University Medical College)
Chen, Geng-Zhen (Department of Minimally Invasive Surgery, Second Affiliated Hospital of Shantou University Medical College)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.14, no.8, 2013 , pp. 4913-4918 More about this Journal
Abstract
Objective: To assess the level of an inpatient population's awareness about hepatitis and primary liver cancer (PLC), the most common type of which is hepatocellular carcinoma (HCC), and then to initiate education of this group. Methods: A survey was conducted with 1300 participants within the inpatient unit in representative tertiary hospitals in the Chaoshan area of China. Structured questionnaires contained demographic data and statements about different aspects of liver cancer and hepatitis. The questionnaires were completed by trained medical practitioners after they had conducted the interviews. Results: One way ANOVA showed that the sample population lacked adequate knowledge about HCC and hepatitis. Stepwise multiple regression analysis demonstrated that the participant's level of education had the greatest impact on their total knowledge score when other variables remained constant. Conclusions: The study demonstrated: a general lack of awareness amongst the participants about the preventative strategies, and the management options available for people with primary liver cancer and hepatitis; education level was an important factor affecting knowledge levels. The demonstrated deficiencies in people's knowledge about hepatitis and HCC, and their lack of subsequent protective behaviours are likely to play an important role in HCC and hepatitis transmission or prevention.
Keywords
Primary liver cancer (PLC); hepatocellular cancer (HCC); hepatitis; knowledge; prevention; education;
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1 Bruix J, Sherman M (2011). Management of hepatocellular carcinoma: an update. Hepatology, 53, 1020-2.   DOI   ScienceOn
2 Deng DJ, Xin HJ (2000). Formation of N-(Nitrosomethyl)urea in stomachs of experimental pigs and human volunteers given fish sauce in vivo. J Agric Food Chem, 48, 2495-8.   DOI   ScienceOn
3 Deng DJ, Ma H, Wang RM, et al (1998). Characterization of N-(Nitrosomethyl)urea in Nitrosated Fermented Fish Products. J Agric Food Chem, 46, 202-5.   DOI   ScienceOn
4 El-Serag HB, Marrero JA, Rudolph L, Reddy KR (2008). Diagnosis and treatment of hepatocellular carcinoma. Gastroenterology, 134, 1752-63.   DOI   ScienceOn
5 Elango KJ, Anandkrishnan N, Suresh A, et al (2011). Mouth self-examination to improve oral cancer awareness and early detection in a high-risk population. Oral Oncol, 47, 620-4.   DOI   ScienceOn
6 Ferlay J, Shin HR, Bray F, et al (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer, 127, 2893-917.   DOI   ScienceOn
7 Giles ML, Grace R, Tai A, et al (2013) Prevention of mother-to-child transmission of hepatitis B virus (HBV). during pregnancy and the puerperium: Current standards of care. Aust N Z J Obstet Gynaecol, 53, 231-5.   DOI   ScienceOn
8 Haorah J, Wang XJ, Xu GP, et al (2001). Determination of total N-nitroso compounds and their precursors in frankfurters, fresh meat, dried salted fish, sauces, tobacco, and tobacco smoke particulates. J Agric Food Chem, 49,6068-78.   DOI   ScienceOn
9 Humphris GM, Field EA (2003). The immediate effect on knowledge, attitudes and intentions in primary care attenders of a patient information leaflet: a randomized control trial replication and extension. Br Dent J, 194, 683-8; discussion 675.   DOI   ScienceOn
10 Kao JH, Chen PJ, Chen DS (2010). Recent advances in the research of hepatitis B virus-related hepatocellular carcinoma: epidemiologic and molecular biological aspects. Adv Cancer Res, 108, 21-72.   DOI   ScienceOn
11 Kim Y J, Lee HS (2005). Single nucleotide polymorphisms associated with hepatocellular carcinoma in patients with chronic hepatitis B virus infection. Intervirology, 48, 10-5.   DOI   ScienceOn
12 Lee YC, Cohet C, Yang YC, et al (2009). Meta-analysis of epidemiologic studies on cigarette smoking and liver cancer. Int J Epidemiol, 38, 1497-511.   DOI   ScienceOn
13 Liu.C, Wang YM, Fan K (2011). Epidemiological and clinical features of hepatitis B virus related liver failure in China. World J Gastroenterol, 17, 3054-9.   DOI   ScienceOn
14 Llovet JM, Burroughs A, Bruix J (2003). Hepatocellular carcinoma. Lancet, 362, 1907-17.   DOI   ScienceOn
15 Li S, Mao M (2012). Next generation sequencing reveals genetic landscape of hepatocellular carcinomas. Cancer Lett, pii: S0304-3835(12)00591-5.
16 Lok AS, Lai CL, Chung HT, et al (1991). Morbidity and mortality from chronic hepatitis B virus infection in family members of patients with malignant and nonmalignant hepatitis B virus-related chronic liver diseases. Hepatology, 13, 834-7.   DOI
17 Lopez-Jornet P, Camacho-Alonso F, Minano FM, Sanchez-Siles M (2012). Evaluation of the different strategies to oral cancer knowledge: a randomized controlled study. Psychooncology, 22, 1618-23.
18 Mitacek EJ, Brunnemann KD, Suttajit M, et al (1999). Exposure to N-nitroso compounds in a population of high liver cancer regions in Thailand: volatile nitrosamine (VNA). levels in Thai food. Food Chem Toxicol, 37, 297-305.   DOI   ScienceOn
19 Montalto G, Cervello M, Giannitrapani L, et al (2002). Epidemiology, risk factors, and natural history of hepatocellular carcinoma. Ann N Y Acad Sci, 963, 13-20.
20 Nobili V, Manco M, Devito R, et al (2008). Lifestyle intervention and antioxidant therapy in children with nonalcoholic fatty liver disease: a randomized, controlled trial. Hepatology, 48, 119-28.   DOI   ScienceOn
21 Parkin DM, Srivatanakul P, Khlat M, et al (1991). Liver cancer in Thailand. I. A case-control study of cholangiocarcinoma. Int J Cancer, 48, 323-8.   DOI
22 Petti S, Scully C (2007). Oral cancer knowledge and awareness: primary and secondary effects of an information leaflet. Oral Oncol, 43, 408-15.   DOI   ScienceOn
23 Peter FS (1975). The toxicology of nitrate, nitrite and n-nitroso compounds. J Sci Food Agric, 26, 1761-70   DOI
24 Plescia M, Richardson LC, Joseph D (2012). New roles for public health in cancer screening. CA Cancer J Clin, 62, 217-9.   DOI   ScienceOn
25 Qin SL, Lin YC, Li CT, Xie XL (2010). Statistical analysis of inpatients with malignancies and death rate in shantou cancer hospital from 2004 to 2008. IMHGN, 16, 889-92.
26 Shariff MI, Cox IJ, Gomaa AI, et al (2009). Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics. Expert Rev Gastroenterol Hepatol, 3, 353-67.   DOI   ScienceOn
27 Stute R, Petridis K, Steinhart H, Biernoth G (2002). Biogenic amines in fish and soy sauces. Eur Food Res Technol, 215, 101-7.   DOI
28 Wakabayashi K, Nagao M, Chung TH, et al (1985). Appearance of direct-acting mutagenicity of various foodstuffs produced in Japan and Southeast Asia on nitrite treatment. Mutat Res, 158, 119-24.   DOI   ScienceOn
29 Wang HH, Chung YC, Sun JL (2012). The effects of education program on knowledge and intention of breast cancer screening in Taiwan. Asian Pac J Cancer Prev, 13, 5545-9.   DOI   ScienceOn
30 Wedding D. Behavior and Medicine. 3rd ed. Seattle: Hogrefe & Huber, 2001. Print.
31 Yao LJ, Huang JY, Huang JH, Huang SS, Liao CH, et al (2007). Analysis on Epidemiological Trend of Class.A and Class.B Infectious Diseases From 1995 to 2005 in Shantou City. Prac Prev Med, 14, 721-3.
32 Yu MC, Tong MJ, Govindarajan S, Henderson BE (1991). Nonviral risk factors for hepatocellular carcinoma in a low-risk population, the non-Asians of Los Angeles County, California. J Natl Cancer Inst, 83, 1820-6.   DOI
33 Yu MC, Yuan JM (2004). Environmental factors and risk for hepatocellular carcinoma. Gastroenterology, 127, S72-8.   DOI   ScienceOn
34 Yu MW, Chang HC, Liaw YF, et al (2000). Familial risk of hepatocellular carcinoma among chronic hepatitis B carriers and their relatives. J Natl Cancer Inst, 92, 1159-64.   DOI   ScienceOn
35 Yu MW, Hsu FC, Sheen IS, et al (1997). Prospective study of hepatocellular carcinoma and liver cirrhosis in asymptomatic chronic hepatitis B virus carriers. Am J Epidemiol, 145, 1039-47.   DOI   ScienceOn
36 Zhang JY, Wang X, Han SG, Zhuang H (1998). A case-control study of risk factors for hepatocellular carcinoma in Henan, China. Am J Trop Med Hyg, 59, 947-51.
37 Zhang LL, Lin JX, Zhang JH (2011). The health survey of primary and secondary school students in Shantou. Chin J School Doctor, 25, 557-8.