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http://dx.doi.org/10.7314/APJCP.2013.14.5.2747

Dietary Phytochemical Index and the Risk of Breast Cancer: A Case Control Study in a Population of Iranian Women  

Bahadoran, Zahra (Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences)
Karimi, Zeinab (Faculty of Nutrition Sciences and Food Technology)
Houshiar-Rad, Anahita (Office, National Nutrition and Food Technology Research Institute)
Mirzayi, Hamid-Reza (Department of Radiation Oncology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences)
Rashidkhani, Bahram (Department of Community Nutrition, National Nutrition and Food Technology Research Institute)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.14, no.5, 2013 , pp. 2747-2751 More about this Journal
Abstract
In this study we assessed the dietary phytochemical index in relation to the risk of breast cancer in women. This case-control study was conducted on 100 incident breast cancer cases and 175 healthy controls. Data regarding socio-demographic factors, medical history, medications, and anthropometric measurements were collected. Dietary data were obtained using a validated food frequency questionnaire and a energy-adjusted dietary phytochemical index (PI) was calculated. The odds ratios of breast cancer were assessed across energyadjusted PI quartile categories. The mean age of participants was $46.2{\pm}8.9$ and $45.9{\pm}9.4$ years in cases and controls, respectively. The mean PI across quartile categories was $13.9{\pm}2.6$, $21.1{\pm}1.8$, $26.7{\pm}2.1$, $41.6{\pm}10.2$ in the first, second, third and fourth quartiles, respectively. After adjustment for all potential confounders, the risk of breast cancer in the forth quartile of dietary PI was significantly decreased (OR=0.08, 95%CI=0.01-0.84). Higher intake of phytochemical-rich foods is associated with lower risk of breast cancer.
Keywords
Breast cancer; diet; phytochemical-rich foods; phytochemical index;
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