Let-7c Inhibits NSCLC Cell Proliferation by Targeting HOXA1 |
Zhan, Min
(Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University)
Qu, Qiang (Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University) Wang, Guo (Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University) Liu, Ying-Zi (Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University) Tan, Sheng-Lan (Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University) Lou, Xiao-Ya (Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University) Yu, Jing (Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University) Zhou, Hong-Hao (Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University) |
1 | Pasquinelli AE, Reinhart BJ, Slack F, et al (2000). Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature, 408, 86-9. DOI ScienceOn |
2 | Pelosi A, Careccia S, Lulli V, et al (2012). miRNA let-7c promotes granulocytic differentiation in acute myeloid leukemia. Oncogene. |
3 | Roush S, Slack FJ (2008). The let-7 family of microRNAs. Trends Cell Biol, 18, 505-16. DOI ScienceOn |
4 | Schultz J, Lorenz P, Gross G, et al (2008). MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. Cell Res, 18, 549-57. DOI ScienceOn |
5 | Shimizu S, Takehara T, Hikita H, et al (2010). The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma. J Hepatol, 52, 698-704. DOI ScienceOn |
6 | Simoncini T, Hafezi-Moghadam A, Brazil DP, et al (2000). Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature, 407, 538-41. DOI ScienceOn |
7 | Suzuki R, Takemura K, Tsutsumi M, et al (2001). Detection of cyclin D1 overexpression by real-time reverse-transcriptase-mediated quantitative polymerase chain reaction for the diagnosis of mantle cell lymphoma. Am J Pathol, 159, 425-9. DOI ScienceOn |
8 | Takamizawa J, Konishi H, Yanagisawa K, et al (2004). Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res, 64, 3753-6. DOI ScienceOn |
9 | Wang M, Wu L, Wang L, et al (2010). Down-regulation of Notch1 by gamma-secretase inhibition contributes to cell growth inhibition and apoptosis in ovarian cancer cells A2780. Biochem Biophys Res Commun, 393, 144-9. DOI ScienceOn |
10 | Yamada H, Yanagisawa K, Tokumaru S, et al (2008). Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at 21q11-21 in human lung cancer. Genes Chromosomes Cancer, 47, 810-8. DOI ScienceOn |
11 | Yin R, Bao W, Xing Y, et al (2012). MiR-19b-1 inhibits angiogenesis by blocking cell cycle progression of endothelial cells. Biochem Biophys Res Commun, 417, 771-6. DOI ScienceOn |
12 | Zha TZ, Hu BS, Yu HF, et al (2012). Overexpression of HOXA1 correlates with poor prognosis in patients with hepatocellular carcinoma. Tumour Biol, 33, 2125-34. DOI ScienceOn |
13 | Zhu T, Starling-Emerald B, Zhang X, et al (2005). Oncogenic transformation of human mammary epithelial cells by autocrine human growth hormone. Cancer Res, 65, 317-24. |
14 | Cho HS, Toyokawa G, Daigo Y, et al (2012). The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene. Int J Cancer, 131, E179-89. DOI ScienceOn |
15 | Esquela-Kerscher A, Trang P, Wiggins JF, et al (2008). The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle, 7, 759-64. DOI |
16 | Feng X, Wu Z, Wu Y, et al (2011). Cdc25A regulates matrix metalloprotease 1 through Foxo1 and mediates metastasis of breast cancer cells. Mol Cell Biol, 31, 3457-71. DOI ScienceOn |
17 | Jinno S, Suto K, Nagata A, et al (1994). Cdc25A is a novel phosphatase functioning early in the cell cycle. EMBO J, 13, 1549-56. |
18 | Gong FX, Xia JL, Yang BW, et al (2011). Effect of let-7c on the proliferation of human hepatocellular carcinoma cell HCCLM3. Zhonghua Gan Zang Bing Za Zhi, 19, 853-6. |
19 | Han HB, Gu J, Zuo HJ, et al (2012). Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer. J Pathol, 226, 544-55. DOI ScienceOn |
20 | Jemal A, Siegel R, Ward E, et al (2007). Cancer statistics, 2007. CA Cancer J Clin, 57, 43-66. DOI ScienceOn |
21 | Johnson CD, Esquela-Kerscher A, Stefani G, et al (2007). The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res, 67, 7713-22. DOI ScienceOn |
22 | Johnson SM, Grosshans H, Shingara J, et al (2005). RAS is regulated by the let-7 microRNA family. Cell, 120, 635-47. DOI ScienceOn |
23 | Kim HH, Kuwano Y, Srikantan S, et al (2009). HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev, 23, 1743-8. DOI ScienceOn |
24 | Kumar MS, Erkeland SJ, Pester RE, et al (2008). Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc Natl Acad Sci U S A, 105, 3903-8. DOI ScienceOn |
25 | Liu Q, Fu H, Sun F, et al (2008). miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. Nucleic Acids Res, 36, 5391-404. DOI ScienceOn |
26 | Mayr C, Hemann MT, Bartel DP. (2007). Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science, 315, 1576-9. DOI ScienceOn |
27 | Mohankumar KM, Xu XQ, Zhu T, et al (2007). HOXA1-stimulated oncogenicity is mediated by selective upregulation of components of the p44/42 MAP kinase pathway in human mammary carcinoma cells. Oncogene, 26, 3998-4008. DOI ScienceOn |
28 | Ohuchida K, Mizumoto K, Lin C, et al (2012). MicroRNA-10a is overexpressed in human pancreatic cancer and involved in its invasiveness partially via suppression of the HOXA1 gene. Ann Surg Oncol, 19, 2394-402. DOI ScienceOn |
29 | Nadiminty N, Tummala R, Lou W, et al (2012). MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth. PLoS One, 7, e32832. DOI ScienceOn |
30 | Navarro A, Marrades RM, Vinolas N, et al (2009). MicroRNAs expressed during lung cancer development are expressed in human pseudoglandular lung embryogenesis. Oncology-Basel, 76, 162-9. DOI ScienceOn |
31 | Abe M, Hamada J, Takahashi O, et al (2006). Disordered expression of HOX genes in human non-small cell lung cancer. Oncol Rep, 15, 797-802. |
32 | Aleem E, Kiyokawa H, Kaldis P (2005). Cdc2-cyclin E complexes regulate the G1/S phase transition. Nat Cell Biol, 7, 831-6. DOI ScienceOn |
33 | Barh D, Malhotra R, Ravi B, et al (2010). MicroRNA let-7: an emerging next-generation cancer therapeutic. Curr Oncol, 17, 70-80. |
34 | Bartel DP (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 116, 281-97. DOI ScienceOn |
35 | Bitu CC, Destro MF, Carrera M, et al (2012). HOXA1 is overexpressed in oral squamous cell carcinomas and its expression is correlated with poor prognosis. BMC Cancer, 12, 146. DOI ScienceOn |
36 | Chariot A, Castronovo V. (1996). Detection of HOXA1 expression in human breast cancer. Biochem Biophys Res Commun, 222, 292-7. DOI ScienceOn |
37 | Chen H, Sukumar S (2003). Role of homeobox genes in normal mammary gland development and breast tumorigenesis. J Mammary Gland Biol Neoplasia, 8, 159-75. DOI ScienceOn |
![]() |