Inhibition of Leptin and Leptin Receptor Gene Expression by Silibinin-Curcumin Combination |
Nejati-Koshki, Kazem
(Department of Medical Biotechnology, Faculty of Medicine, Tabriz University of Medical Sciences)
Akbarzadeh, Abolfazl (Department of Medical Nanotechnology, Faculty of Advanced Medical Sciences) Pourhasan-Moghaddam, Mohammad (Department of Medical Biotechnology, Faculty of Medicine, Tabriz University of Medical Sciences) Abhari, Alireza (Department of Clinical Biochemistry, Faculty of Medicine, Tabriz University of Medical Sciences) Dariushnejad, Hassan (Department of Medical Biotechnology, Faculty of Medicine, Tabriz University of Medical Sciences) |
1 | Boominathan, Lakshmanane (2009). Curcumin Functions as a Positive Regulator of miRNA Processing & a Negative Regulator of Cancer Stem Cell Proliferation. |
2 | Chiu TL, Su CC (2009). Curcumin inhibits proliferation and migration by increasing the Bax to Bcl-2 ratio and decreasing NF-kappaBp65 expression in breast cancer MDA-MB-231 cells. Int J Mol Med, 23, 469-75. |
3 | Cottrell EC, Mercer JG (2012). Leptin receptors. Handb Exp Pharmacol, 3-21. |
4 | De Kok TM, van Breda SG, Manson MM (2008). Mechanisms of combined action of different chemopreventive dietary compounds: a review. Eur J Nutr, 47, 51-9. DOI ScienceOn |
5 | Dieudonne MN, Machinal-Quelin F, Serazin-Leroy V, et al (2002). Leptin mediates a proliferative response in human MCF7 breast cancer cells. Biochem Biophys Res Commun, 293, 622-8. DOI ScienceOn |
6 | Fazeli M, Zarkesh-Esfahani H, Wu Z, et al (2006). Identification of a monoclonal antibody against the leptin receptor that acts as an antagonist and blocks human monocyte and T cell activation. J Immunol Methods, 312, 190-200. DOI ScienceOn |
7 | Fusco R, Galgani M, Procaccini C, et al (2010). Cellular and molecular crosstalk between leptin receptor and estrogen receptor-{alpha} in breast cancer: molecular basis for a novel therapeutic setting. Endocr Relat Cancer, 17, 373-82. DOI ScienceOn |
8 | Garcia-Robles MJ, Segura-Ortega JE, Fafutis-Morris M (2013). The biology of leptin and its implications in breast cancer: a general view. J Interferon Cytokine Res, [Epub ahead of print]. |
9 | Go O, Freeman RH, Reams GP, et al (2013). Obesity hypertension: pathophysiological role of leptin in neuroendocrine dysregulation. Am J Med Sci, [Epub ahead of print] |
10 | Gonzalez RR, Watters A, Xu Y, et al (2009). Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer. Breast Cancer Res, 11, 36. DOI ScienceOn |
11 | Hardwick JC, Van Den Brink GR, Offerhaus GJ, et al (2001). Leptin is a growth factor for colonic epithelial cells. Gastroenterology, 121, 79-90. DOI ScienceOn |
12 | Hu X, Juneja SC, Maihle NJ, et al (2002). Leptin.a growth factor in normal and malignant breast cells and for normal mammary gland development. J Natl Cancer Inst, 94, 1704-11. DOI ScienceOn |
13 | Ishikawa M, Kitayama J, Nagawa H (2004). Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer. Clin Cancer Res, 10, 4325-31. DOI ScienceOn |
14 | Kaur M, Agarwal R (2007). Silymarin and epithelial cancer chemoprevention: how close we are to bedside. Toxicol Appl Pharmacol, 224, 350-9. DOI ScienceOn |
15 | Kelesidis T, Kelesidis I, Chou S, et al (2010). Narrative review: the role of leptin in human physiology: emerging clinical applications. Ann Intern Med, 152, 93-100. DOI ScienceOn |
16 | Liu Z, Uesaka T, Watanabe H, et al (2001). High fat diet enhances colonic cell proliferation and carcinogenesis in rats by elevating serum leptin. Int J Oncol, 19, 1009-14. |
17 | Koda M, Sulkowska M, Kanczuga-Koda L, et al (2007). Expression of leptin and its receptor in female breast cancer in relation with selected apoptotic markers. Folia Histochem Cytobiol, 45, 187-91. |
18 | Laud K, Gourdou I, Pessemesse L, et al (2002). Identification of leptin receptors in human breast cancer: Functional activity in the T47-D breast cancer cell line. Mol Cell Endocrinol, 188, 219-26. DOI ScienceOn |
19 | Lin CJ, Sukarieh R, Pelletier J (2009). Silibinin inhibits translation initiation: implications for anticancer therapy. Mol Cancer Ther, 8, 1606-12. DOI ScienceOn |
20 | Loffler S, Aust G, Kohler U, et al (2001). Evidence of leptin expression in normal and polycystic human ovaries. Mol Hum Reprod, 7, 1143-9. DOI ScienceOn |
21 | Maymo JL, Perez AP, Gambino Y, et al (2011). Leptin gene expression in the placenta--regulation of a key hormone in trophoblast proliferation and survival. Placenta, 2, 146-53. |
22 | Mix H, Widjaja A, Jandl O (2000). Expression of leptin and leptin receptor isoforms in the human stomach. Gut, 47, 481-6. DOI ScienceOn |
23 | Morroni M, De Matteis R, Palumbo C, et al (2004). In vivo leptin expression in cartilage and bone cells of growing rats and adult humans. J Anat, 205, 291-6. DOI ScienceOn |
24 | Nejati-Koshki K, Zarghami N, Pourhassan-Moghaddam M, et al (2012). Inhibition of leptin gene expression and secretion by silibinin: possible role of estrogen receptors. Cytotechnology, 64, 719-26. DOI ScienceOn |
25 | Sareen R, Jain N, Pandit V (2013). Curcumin: A boon to Colonic Diseases. Curr Drug Targets, 14. [Epub ahead of print] |
26 | Oda A, Taniguchi T, Yokoyama M (2001). Leptin stimulates rat aortic smooth muscle cell proliferation and migration. Kobe J Med Sci, 47, 141-50. |
27 | Peters JH, Simasko SM, Ritter RC (2007). Leptin analog antagonizes leptin effects on food intake and body weight but mimics leptin-induced vagal afferent activation. Endocrinology, 148, 2878-85. DOI ScienceOn |
28 | Ray A, Cleary MP (2010). Leptin as a potential therapeutic target for breast cancer prevention and treatment. Expert Opin Ther Targets, 14, 443-51. DOI ScienceOn |
29 | Siegel R, Naishadham D, Jemal A (2012). Cancer statistics 2012. CA Cancer J Clin, 62, 10-29. DOI ScienceOn |
30 | Singh RP, Sharma G, Dhanalakshmi S, et al (2009). Suppression of advanced human prostate tumor growth in athymic mice by silibinin feeding is associated with reduced cell proliferation, increased apoptosis, and inhibition of angiogenesis. Mol Cancer Ther, 8, 1606-12. DOI ScienceOn |
31 | Solberg R, Aas V, Thoresen GH, et al (2005). Leptin expression in human primary skeletal muscle cells is reduced during differentiation. J Cell Biochem, 96, 89-96. DOI ScienceOn |
32 | Soyupek S, Arma.an A, Serel TA, et al (2005). Leptin expression in the testicular tissue of fertile and infertile men. Arch Androl, 51, 239-46. DOI ScienceOn |
33 | Wazir U, Al Sarakbi W, Jiang WG, et al (2012). Evidence of an autocrine role for leptin and leptin receptor in human breast cancer. Cancer Genomics Proteomics, 9, 383-7. |
34 | Yom CK, Lee KM, Han W, et al (2013). Leptin as a potential target for estrogen receptor-positive breast cancer. J Breast Cancer, 16, 138-45. DOI ScienceOn |
35 | Yi KW, Shin JH, Seo HS, et al (2008). Role of estrogen receptor-alpha and -beta in regulating leptin expression in 3T3-L1 adipocytes. Obesity (Silver Spring), 16, 2393-9. DOI ScienceOn |
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