Radiation-induced Cochlea Hair Cell Death: Mechanisms and Protection |
Tan, Pei-Xin
(Department of Radiation Oncology, Nanfang Hospital, Southern Medical University)
Du, Sha-Sha (Department of Radiation Oncology, Nanfang Hospital, Southern Medical University) Ren, Chen (Department of Radiation Oncology, Nanfang Hospital, Southern Medical University) Yao, Qi-Wei (Department of Radiation Oncology, Nanfang Hospital, Southern Medical University) Yuan, Ya-Wei (Department of Radiation Oncology, Nanfang Hospital, Southern Medical University) |
1 | Verheij M, Bartelink H (2000). Radiation-induced apoptosis. Cell Tissue Res, 301, 133-42. DOI ScienceOn |
2 | Wang J, Ruel J, Ladrech S, et al (2007). Inhibition of the c-Jun N-terminal kinase-mediated mitochondrial cell death pathway restores auditory function in sound-exposed animals. Mol Pharmacol, 71, 654-66. |
3 | Xie LH, Tang AZ, Yin SH, Tan SH (2012). [Protective effects of n-acetylcysteine on cochlear damage occuring in guinea pigs exposed to irradiation]. Zhonghua Yi Xue Za Zhi, 92, 989-92. |
4 | Zine A, van de Water TR (2004). The MAPK/JNK signalling pathway offers potential therapeutic targets for the prevention of acquired deafness. Curr Drug Targets CNS Neurol Disord, 3, 325-32. DOI |
5 | Awwad HK (1990). Radiation Oncology: Radiobiological and Physiological Perspectives. Late reacting tissues: radiation damage to central nervous system, The Netherlands: Kluger Academic Publishers. |
6 | Baker K, Staecker H (2012). Low dose oxidative stress induces mitochondrial damage in hair cells. Anat Rec (Hoboken), 295, 1868-76. DOI ScienceOn |
7 | Bertolaso L, Martini A, Bindini D, et al (2001). Apoptosis in the OC-k3 immortalized cell line treated with different agents. Audiology, 40, 327-35. DOI |
8 | Bhandare N, Antonelli PJ, Morris CG, et al (2007). Ototoxicity after radiotherapy for head and neck tumors. Int J Radiat Oncol Biol Phys, 67, 469-79. DOI ScienceOn |
9 | Bohne BA, Marks JE, Glasgow GP (1985). Delayed effects of ionizing radiation on the ear. Laryngoscope, 95, 818-28. |
10 | De Flora S, Izzotti A, D'Agostini F, Balansky RM (2001). Mechanisms of N-acetylcysteine in the prevention of DNA damage and cancer, with special reference to smokingrelated endpoints. Carcinogenesis, 22, 999-1013. DOI ScienceOn |
11 | Cheng AG, Huang T, Stracher A, et al (1999). Calpain inhibitors protect auditory sensory cells from hypoxia and neurotrophin-withdrawal induced apoptosis. Brain Res, 850, 234-43. DOI ScienceOn |
12 | Bourhis J, Blanchard P, Maillard E, et al (2011). Effect of amifostine on survival among patients treated with radiotherapy: a meta-analysis of individual patient data. J Clin Oncol, 29, 2590-7. DOI ScienceOn |
13 | Chen WC, Jackson A, Budnick AS, et al (2006). Sensorineural hearing loss in combined modality treatment of nasopharyngeal carcinoma. Cancer, 106, 820-9. DOI ScienceOn |
14 | Cheng AG, Cunningham LL, Rubel EW (2005). Mechanisms of hair cell death and protection. Curr Opin Otolaryngol Head Neck Surg, 13, 343-8. DOI ScienceOn |
15 | Doctrow SR, Lopez A, Schock AM, et al (2012). A synthetic superoxide dismutase/catalase mimetic EUK-207 mitigates radiation dermatitis and promotes wound healing in irradiated rat skin. J Invest Dermatol, 133, 1088-96. |
16 | Feghali JG, Liu W, Van De Water TR (2001). L-n-acetyl-cysteine protection against cisplatin-induced auditory neuronal and hair cell toxicity. Laryngoscope, 111, 1147-55. DOI ScienceOn |
17 | Ferri KF, Kroemer G (2001). Organelle-specific initiation of cell death pathways. Nat Cell Biol, 3, 255-63. DOI ScienceOn |
18 | Fleury B, Lapeyre M (2010). Tolerance of normal tissues to radiation therapy: ear. Cancer Radiother, 14, 284-9. DOI ScienceOn |
19 | Hitchcock YJ, Tward JD, Szabo A, Bentz BG, Shrieve DC (2009). Relative contributions of radiation and cisplatin-based chemotherapy to sensorineural hearing loss in headand-neck cancer patients. Int J Radiat Oncol Biol Phys, 73, 779-88. DOI ScienceOn |
20 | Hensley ML, Hagerty KL, Kewalramani T, et al (2009). American Society of Clinical Oncology 2008 clinical practice guideline update: use of chemotherapy and radiation therapy protectants. J Clin Oncol, 27, 127-45. |
21 | Hettinger K, Vikhanskaya F, Poh MK, et al (2007). C-Jun promotes cellular survival by suppression of PTEN. Cell Death Differ, 14, 218-29. DOI ScienceOn |
22 | Honore HB, Zarowski A, Moller K, Grau C (2002). Radiotherapy-induced ear toxicity. Radiother Oncol, 65, 9-16. DOI ScienceOn |
23 | Hua C, Bass JK, Khan R, Kun LE, Merchant TE (2008). Hearing loss after radiotherapy for pediatric brain tumors: effect of cochlear dose. Int J Radiat Oncol Biol Phys, 72, 892-9. DOI ScienceOn |
24 | Iliakis G (1991). The role of DNA double strand breaks in ionizing radiation-induced killing of eukaryotic cells. Bioessays, 13, 641-8. DOI |
25 | Jiang H, Sha SH, Forge A, Schacht J (2006). Caspase-independent pathways of hair cell death induced by kanamycin in vivo. Cell Death Differentiation, 13, 20-30. DOI ScienceOn |
26 | Kim CH, Kang SU, Pyun J, et al (2008). Epicatechin protects auditory cells against cisplatin-induced death. Apoptosis, 13, 1184-94. DOI |
27 | Linskey ME, Johnstone PA (2003). Radiation tolerance of normal temporal bone structures: implications for gamma knife stereotactic radiosurgery. Int J Radiat Oncol Biol Phys, 57, 196-200. DOI ScienceOn |
28 | Lessa RM, Oliveira JA, Rossato M, Ghilardi Netto T (2009). Analysis of the cytoprotective effect of amifostine on the irradiated inner ear of guinea pigs: an experimental study. Braz J Otorhinolaryngol, 75, 694-700. DOI |
29 | Liang J, Wang D, Renaud G, et al (2012). The stat3/socs3a pathway is a key regulator of hair cell regeneration in zebrafish. [corrected]. J Neurosci, 32, 10662-73. DOI ScienceOn |
30 | Li JJ, Guo YK, Tang QL, et al (2010). Prospective study of sensorineural hearing loss following radiotherapy for nasopharyngeal carcinoma. J Laryngol Otol, 124, 32-6. DOI ScienceOn |
31 | Low WK, Fong KW (1998). Long-term hearing status after radiotherapy for nasopharyngeal carcinoma. Auris Nasus Larynx, 25, 21-4. DOI ScienceOn |
32 | Low WK, Kong SW, Tan MG (2010). Ototoxicity from combined Cisplatin and radiation treatment: an in vitro study. Int J Otolaryngol, 2010, 523976. |
33 | Low WK, Burgess R, Fong KW, Wang DY (2005). Effect of radiotherapy on retro-cochlear auditory pathways. Laryngoscope, 115, 1823-6. DOI ScienceOn |
34 | Low WK, Sun L, Tan MG, Chua AW, Wang DY (2008). L-N-Acetylcysteine protects against radiation-induced apoptosis in a cochlear cell line. Acta Otolaryngol, 128, 440-5. DOI ScienceOn |
35 | Low WK, Michelle GK, Tan. Sun L, et al (2006b). Dose-dependant radiation-induced apoptosis in a cochlear cell-line. Apoptosis, 11, 2127-36. DOI |
36 | Mansour HH, Hafez HF, Fahmy NM, Hanafi N (2008). Protective effect of N-acetylcysteine against radiation induced DNA damage and hepatic toxicity in rats. Biochem Pharmacol, 75, 773-80. DOI ScienceOn |
37 | Marchenko ND, Zaika A, Moll UM (2000). Death signal-induced localization of p53 protein to mitochondria: a potential role in apoptotic signaling. J Biol Chem, 275, 16202-12. DOI ScienceOn |
38 | Pyun JH, Kang SU, Hwang HS, et al (2011). Epicatechin inhibits radiation-induced auditory cell death by suppression of reactive oxygen species generation. Neuroscience, 199, 410-20. DOI ScienceOn |
39 | Mikkelsen RB, Wardman P (2003). Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms. Oncogene, 22, 5734-54. DOI ScienceOn |
40 | Petsuksiri J, Sermsree A, Thephamongkhol K, et al (2011). Sensorineural hearing loss after concurrent chemoradiotherapy in nasopharyngeal cancer patients. Radiat Oncol, 6, 19. DOI ScienceOn |
41 | Reliene R, Fischer E, Schiest RH (2004). Effect of N-acetylcysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice. Cancer Res, 63, 5148-53. |
42 | Sabapathy K (2012). Role of the JNK pathway in human diseases. Prog Mol Biol Transl Sci, 106, 145-69. DOI ScienceOn |
43 | Seidman MD, Vivek P (2004). Intratympanic treatment of hearing loss with novel and traditional agents. Otolaryngol Clin North Am, 37, 973-90. DOI ScienceOn |
44 | Selzer E, Hebar A (2012). Basic principles of molecular effects of irradiation. Wien Med Wochenschr, 162, 47-54. DOI ScienceOn |
45 | Wang J, Ladrech S, Pujol R (2004). Caspase inhibitors, but not c-Jun NH2-terminal kinase inhibitor treatment, prevent cisplatin-induced hearing loss. Cancer Res, 64, 9217-24. DOI ScienceOn |
46 | Tabuchi K, Nishimura B, Nakamagoe M, et al (2011). Ototoxicity: mechanisms of cochlear impairment and its prevention. Curr Med Chem, 18, 4866-71. DOI |
47 | Pan CC, Eisbruch A, Lee JS, et al (2005). Prospective study of inner ear radiation dose and hearing loss in head-and-neck cancer patients. Int J Radiat Oncol Biol Phys, 61, 1393-402. DOI ScienceOn |
48 | Devarajan P, Savoca M, Castaneda MP, et al (2002). Cisplatin-induced apoptosis in auditory cells: role of death receptor and mitochondrial pathways. Hear Res, 174, 45-54. DOI ScienceOn |
49 | Gao F, Fish BL, Szabo A, et al (2012). Short-term treatment with a SOD/catalase mimetic, EUK-207, mitigates pneumonitis and fibrosis after single-dose total-body or whole-thoracic irradiation. Radiat Res, 178, 468-80. DOI |
50 | Low WK, Toh ST, Wee J, Fook-Chong SM, Wang DY (2006a). Sensorineural hearing loss after radiotherapy and chemoradiotherapy: a single, blinded, randomized study. J Clin Oncol, 24, 1904-9. DOI ScienceOn |
51 | Sha SH, Taylor R, Forge A, Schacht J (2001). Differential vulnerability of basal and apical hair cells is based on intrinsic susceptibility to free radicals. Hear Res, 155, 1-8. DOI ScienceOn |