Prognostically Significant Fusion Oncogenes in Pakistani Patients with Adult Acute Lymphoblastic Leukemia and their Association with Disease Biology and Outcome |
Sabir, Noreen
(Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab)
Iqbal, Zafar (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Aleem, Aamer (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Awan, Tashfeen (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Naeem, Tahir (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Asad, Sultan (Centre for Advanced Molecular Biology, University of Lahore) Tahir, Ammara H (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Absar, Muhammad (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Hasanato, Rana MW (Department of Medicine, Microbiology Section, College of Medicine and King Khalid University Hospital, King Saud University) Basit, Sulman (Department of Medicine, Biochemistry Research Section, College of Medicine and King Khalid University Hospital, King Saud University) Chishti, Muhammad Azhar (Department of Medicine, Biochemistry Research Section, College of Medicine and King Khalid University Hospital, King Saud University) Ul-Haque, Muhammad Faiyaz (Department of Pathology, Molecular Genetic Pathology, College of Medicine and King Khalid University Hospital, King Saud University) Khalid, Ahmad Muktar (School of Biology Sciences, University of Sargodha) Sabar, Muhammad Farooq (Centre for Advanced Molecular Biology, University of Lahore) Rasool, Mahmood (Centre of Excellence in Genomic Medicine Research, King Abdulaziz University) Karim, Sajjad (Centre of Excellence in Genomic Medicine Research, King Abdulaziz University) Khan, Mahwish (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Samreen, Baila (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Akram, Afia M (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Siddiqi, Muhammad Hassan (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Shahzadi, Saba (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Shahbaz, Sana (Hematology, Oncology and Pharmacogenetic Engineering Sciences Group, Health Sciences Laboratories, Faculty of Biological Sciences, Department of Zoology, University of the Punjab) Ali, Agha Shabbir (Post Graduate Medical Institute & Institute of Child Health) |
1 | Andreasson P, Schwaller J, Anastasiadou E, et al (2001). The expression of ETV6/CBFA2 (TEL/AML1) is not sufficient for the transformation of hematopoietic cell lines in vitro or the induction of hematologic disease in vivo. Cancer Genet Cytogenet, 130, 93-104. DOI |
2 | Bassan R (2005). Evolving strategies for the management of high-risk adult acute lymphoblastic leukemia. Haematologica, 90, 1299. |
3 | Burmeister T. Gokbuget N, Schwartz S, et al (2010). Clinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemia. Haematologica, 95, 241-6. DOI |
4 | Debaraj PE, Foroni L, Janossy G, et al (1995). Expression of the E2A-PBX1 fusion transcripts in t (1; 19) (q23; p13) and der (19) t (1; 19) at diagnosis and in remission of acute lymphoblastic leukemia with different B lineage immunophenotypes. Leukemia, 9, 821-5. |
5 | Faderl S, Kantarjian HM, Talpaz M, Estrov Z (1998). Clinical significance of cytogenetic abnormalities in adult acute lymphoblastic leukemia. Blood, 91, 3995-4019. |
6 | Faiz M, Iqbal QJ, Qureshi A (2011). High prevalence of BCR-ABL fusion transcripts with poor prognostic impact among adult ALL patients: report from Pakistan. Asia Pac J Clin Oncol, 7, 47-55. |
7 | Fielding AK (2010). How I treat Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood, 116, 3409-17. DOI |
8 | Foa R, Vitale A, Mancini M, et al (2003). E2A-PBX1 fusion in adult acute lymphoblastic leukaemia: biological and clinical features. Br J Haematol, 120, 484-7. DOI |
9 | Harrison CJ, Foroni L (2002). Cytogenetics and molecular genetics of acute lymphoblastic leukemia. Rev Clin Exp Hematol, 6, 91-113. DOI |
10 | Iacobucci I, Papayannidis C, Lonetti A, et al (2012). Cytogenetic and molecular predictors of outcome in acute lymphocytic leukemia: recent developments. Curr Hematol Malig Rep, 7, 133-43. DOI ScienceOn |
11 | Iqbal Z (2006). Frequency of chromosomal abnormalities and corresponding fusion oncogenes in acute lymphoblastic leukemia (ALL) patients of Pakistan and its implication in differential diagnosis and prognosis of leukemia. Haematologica, 91, 65. |
12 | Iqbal Z, Tanveer A (2006) Incidence of different fusion oncogenes in acute lymphoblastic leukemia (ALL) patients from Pakistan: possible implication in differential diagnosis, prognosis, treatment and management of ALL. Haematologica, 91, 64. |
13 | Iqbal Z, Akhtar T, Iqbal M, et al (2009). First comprehensive report of strong interplay of genetic and environmental factors as well as high degree of ethnic and geographical variations in biology of leukemia as manifested by frequencies of common fusion oncogenes of prognostic significance associated with different Leukemic subtypes in Pakistani population. In: Online proceedings American Association for Cancer Research 100TH Annual Meeting, April 18-22, Colorado, Denver. |
14 | Mancini M, Scappaticci D, Cimino G, et al (2005). A comprehensive genetic classification of adult acute lymphoblastic leukemia (ALL): analysis of the GIMEMA 0496 protocol. Blood, 105, 3434-41. DOI |
15 | Moorman AV, Harrison CJ, Buck GA, et al (2007). Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the medical research council (MRC) UKALLXII/eastern cooperative oncology group (ECOG) 2993 trial. Blood, 109, 3189-97. DOI ScienceOn |
16 | Soverini S, Colarossi S, Gnani A, et al (2007). Resistance to dasatinib in Philadelphia-positive leukemia patients and the presence or the selection of mutations at residues 315 and 317 in the BCR-ABL kinase domain. Haematologica, 92, 401-4. DOI |
17 | Pui CH, Evans WE (2006). Treatment of acute lymphoblastic leukemia. N Engl J Med, 354, 166-78. DOI |
18 | Pui CH, Robison LL, Look AT (2008). Acute lymphoblastic leukaemia. Lancet, 371, 1030-43. DOI |
19 | Pui CH, Sandlund JT, Pei D, et al (2004). Improved outcome for children with acute lymphoblastic leukemia: results of total therapy study XIIIB at St jude children's research hospital. Blood, 104, 2690-6. DOI |
20 | The groupe franGais de cytoghetique hematologique (1996). Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologic findings and outcome. Blood, 87, 3135-42. |
21 | Thomas X, Boiron JM, Huguet F, et al (2004). Outcome of treatment in adults with acute lymphoblastic leukemia: analysis of the LALA-94 trial. J Clin Oncol, 22, 4075-86. DOI ScienceOn |
22 | Van Dongen JJ, Macintyre EA, Gabert JA, et al (1999). Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia. Leukemia, 13, 1901-28. DOI |
23 | Xing H, Yang X, Liu T, et al (2012). The study of resistant mechanisms and reversal in an imatinib resistant Ph+ acute lymphoblastic leukemia cell line. Leuk Res, 36, 509-13. DOI |