HMGB1 Promotes the Synthesis of Pro-IL-1β and Pro-IL-18 by Activation of p38 MAPK and NF-κB Through Receptors for Advanced Glycation End-products in Macrophages |
He, Qiang
(Institute of Integrated Traditional Medicine and Western Medicine, Beijing Friendship Hospital, Capital Medical University)
You, Hong (Liver Research Center, Beijing Friendship Hospital, Capital Medical University) Li, Xin-Min (Liver Research Center, Beijing Friendship Hospital, Capital Medical University) Liu, Tian-Hui (Liver Research Center, Beijing Friendship Hospital, Capital Medical University) Wang, Ping (Liver Research Center, Beijing Friendship Hospital, Capital Medical University) Wang, Bao-En (Institute of Integrated Traditional Medicine and Western Medicine, Beijing Friendship Hospital, Capital Medical University) |
1 | Andersson U, Wang H, Palmblad K, et al (2000). High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med, 192, 565-70. DOI |
2 | Bauernfeind FG, Horvath G, Stutz A, et al (2009). Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol, 183, 787-91. DOI |
3 | Mantovani A, Allavena P, Sica A, Balkwill F (2008). Cancerrelated inflammation. Nature, 454, 436-44. DOI ScienceOn |
4 | Carrascal MT, Mendoza L, Valcarcel M, et al (2003). Interleukin-18 binding protein reduces b16 melanoma hepatic metastasis by neutralizing adhesiveness and growth factors of sinusoidal endothelium. Cancer Res, 63, 491-7. |
5 | Eissa SA, Zaki SA, El-Maghraby et al (2005). Importance of serum IL-18 and RANTES as markers for breast carcinoma progression. J Egypt Natl Canc Inst, 17, 51-5. |
6 | Klune JR, Dhupar R, Cardinal J, et al (2008). HMGB1: endogenous danger signaling. Mol Med, 14, 476-84. |
7 | Martinon F (2010). Signaling by ROS drives inflammasome activation. Eur J Immunol, 40, 616-9. DOI ScienceOn |
8 | Lewis AM, Varghese S, Xu H, et al (2006). Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment. J Transl Med, 4, 48. DOI |
9 | Lotze MT, Tracey KJ (2005). High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol, 5, 331-42. DOI |
10 | Luan ZG, Zhang H, Yang PT, et al (2010). HMGB1 activates nuclear factor-kappaB signaling by RAGE and increases the production of TNF-alpha in human umbilical vein endothelial cells. Immunobiology, 215, 956-62. DOI |
11 | Merendino RA, Gangemi S, Ruello A, et al (2001). Serum levels of interleukin-18 and sICAM-1 in patients affected by breast cancer: preliminary considerations. Int J Biol Markers, 16, 126-9. |
12 | Sha Y, Zmijewski J, Xu Z, et al (2008). HMGB1 develops enhanced proinflammatory activity by binding to cytokines. J Immunol, 180, 2531-7. DOI |
13 | Okamoto M, Liu W, Luo Y, et al (2010). Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta. J Biol Chem, 285, 6477-88. DOI |
14 | Park JS, Gamboni-Robertson F, He Q, et al (2006). High mobility group box 1 protein interacts with multiple Tolllike receptors. Am J Physiol Cell Physiol, 290, C917-24. |
15 | Schroder K, Tschopp J (2010). The inflammasomes. Cell, 140, 821-32. DOI |
16 | Wang P, Cong M, Liu TH, et al (2010). Primary isolated hepatic oval cells maintain progenitor cell phenotypes aftertwo-year prolonged cultivation. J Hepatol, 53, 863-71. DOI |
17 | Sims GP, Rowe DC, Rietdijk ST, et al (2010). HMGB1 and RAGE in inflammation and cancer. Annu Rev Immunol, 28, 367-88. DOI |
18 | Tang D, Kang R, 3rd ZHJ, et al (2010). High-mobility group box 1 and cancer. Biochim Biophys Acta, 1799, 131-40. DOI |
19 | Tschopp J, Schroder K (2010). NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production. Nat Rev Immunol, 10, 210-5. DOI ScienceOn |
20 | Yang D, Chen Q, Yang H, et al (2007). High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin. J Leukoc Biol, 81, 59-66. |
21 | Yang J, Chen L, Yang J, et al (2011). High mobility group box- 1 induces migration of vascular smooth muscle cells via TLR4-dependent PI3K/Akt pathway activation. Mol Biol Rep, 39, 3361-7. |
22 | Ye ZB, Ma T, Li H, et al (2007). Expression and significance of intratumoral interleukin-12 and interleukin-18 in human gastric carcinoma. World J Gastroenterol, 13, 1747-51. DOI |