Genetic Variants of NBS1 Predict Clinical Outcome of Platinum-based Chemotherapy in Advanced Non-small Cell Lung Cancer in Chinese |
Xu, Jia-Li
(Department of Oncology, The First Affiliated Hospital of Nanjing Medical University)
Hu, Ling-Min (Department of Epidemiology and Biostatistics, MOE Key Laboratory of Modern Toxicology, School of Public Health, Nanjing Medical University) Huang, Ming-De (Department of Oncology, Huai'an No.1 hospital affiliated to Nanjing Medical University) Zhao, Wan (Department of Oncology, The First Affiliated Hospital of Nanjing Medical University) Yin, Yong-Mei (Department of Oncology, The First Affiliated Hospital of Nanjing Medical University) Hu, Zhi-Bin (Department of Epidemiology and Biostatistics, MOE Key Laboratory of Modern Toxicology, School of Public Health, Nanjing Medical University) Ma, Hong-Xia (Department of Epidemiology and Biostatistics, MOE Key Laboratory of Modern Toxicology, School of Public Health, Nanjing Medical University) Shen, Hong-Bing (Department of Epidemiology and Biostatistics, MOE Key Laboratory of Modern Toxicology, School of Public Health, Nanjing Medical University) Shu, Yong-Qian (Department of Oncology, The First Affiliated Hospital of Nanjing Medical University) |
1 | Tran H, Shi G, Li G, et al (2004). Mutant Nbs1 enhances cisplatin-induced DNA damage and cytotoxicity in head and neck cancer. Otolaryngol Head Neck Surg, 131, 477-84. DOI |
2 | Wang LE, Yin M, Dong Q, et al (2011). DNA repair capacity in peripheral lymphocytes predicts survival of patients with non-small-cell lung cancer treated with first-line platinumbased chemotherapy. J Clin Oncol, 29, 4121-8. DOI |
3 | Wang Y, Cortez D, Yazdi P, et al (2000). BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev, 14, 927-39. |
4 | Yang MH (2006). Increased NBS1 expression is a marker of aggressive head and neck cancer and overexpression of NBS1 contributes to transformation. Clinic Cancer Res, 12, 507-15. DOI |
5 | Zhang Y, Zhou J, Lim CU (2006). The role of NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint control. Cell Res, 16, 45-54. DOI |
6 | Zheng J, Zhang C, Jiang L, et al (2011). Functional NBS1 polymorphism is associated with occurrence and advanced disease status of nasopharyngeal carcinoma. Mol Carcinog, 50, 689-96. DOI |
7 | Zienolddiny S (2005). Polymorphisms of DNA repair genes and risk of non-small cell lung cancer. Carcinogenesis, 27, 560-7. DOI |
8 | Kobayashi J (2004). Molecular mechanism of the recruitment of NBS1/hMRE11/hRAD50 complex to DNA double-strand breaks: NBS1 binds to gamma-H2AX through FHA/BRCT domain. J Radiat Res (Tokyo), 45, 473-8. DOI |
9 | Kobayashi J, Antoccia A, Tauchi H, et al (2004). NBS1 and its functional role in the DNA damage response. DNA Repair (Amst), 3, 855-61. |
10 | Lan Q, Shen M, Berndt SI, et al (2005). Smoky coal exposure, NBS1 polymorphisms, p53 protein accumulation, and lung cancer risk in Xuan Wei, China. Lung Cancer, 49, 317-23. DOI |
11 | Landi S, Gemignani F, Canzian F, et al (2006). DNA repair and cell cycle control genes and the risk of young-onset lung cancer. Cancer Res, 66, 11062-9. DOI |
12 | Le Chevalier T (2010). Adjuvant chemotherapy for resectable non-small-cell lung cancer: where is it going? Ann Oncol, 21, vii196. DOI |
13 | Li C, Wang LE, Wei Q (2009). DNA repair phenotype and cancer susceptibility-a mini review. Int J Cancer, 124, 999-1007. DOI |
14 | Loizidou MA, Cariolou MA, Neuhausen SL, et al (2010). Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population. Breast Cancer Res Treat, 121, 147-56. DOI |
15 |
Lu J, Wei Q, Bondy ML, et al (2006). Polymorphisms and haplotypes of the NBS1 gene are associated with risk of sporadic breast cancer in non-Hispanic white women |
16 | Margulis V, Lin J, Yang H, et al (2008). Genetic susceptibility to renal cell carcinoma: the role of DNA double-strand break repair pathway. Cancer Epidemiol Biomarkers Prev, 17, 2366-73. DOI |
17 | Maser RS, Monsen KJ, Nelms BE, Petrini JH (1997). hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks. Mol Cell Biol, 17, 6087-96. DOI |
18 | Medina PP, Ahrendt SA, Pollan M, et al (2003). Screening of homologous recombination gene polymorphisms in lung cancer patients reveals an association of the NBS1- 185Gln variant and p53 gene mutations. Cancer Epidemiol Biomarkers Prev, 12, 699-704. |
19 | MeiXia L, Jiachun L, XiaoBo Y, et al (2009). Association between the NBS1 E185Q polymorphism and cancer risk: a meta-analysis. BMC Cancer, 9, 124. DOI |
20 | Merika M, Orkin SH (1993). DNA-binding specificity of GATA family transcription factors. Mol Cell Biol, 13, 3999-4010. DOI |
21 | Mosor M, Ziolkowska I, Januszkiewiczlewandowska D, Nowak J (2008). Polymorphisms and haplotypes of the NBS1 gene in childhood acute leukaemia. Eur J Cancer, 44, 2226-32. DOI |
22 | Naruke T, Tsuchiya R, Kondo H, Asamura H (2001). Prognosis and survival after resection for bronchogenic carcinoma based on the 1997 TNM-staging classification: the Japanese experience. Ann Thorac Surg, 71, 1759-64. DOI ScienceOn |
23 | Ohe Y, Ohashi Y, Kubota K, et al (2007). Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: Four- Arm Cooperative Study in Japan. Ann Oncol, 18, 317-23. |
24 | Ott K, Rachakonda PS, Panzram B, et al (2011). DNA repair gene and MTHFR gene polymorphisms as prognostic markers in locally advanced adenocarcinoma of the esophagus or stomach treated with cisplatin and 5-fluorouracil-based neoadjuvant chemotherapy. Ann Surg Oncol, 18, 2688-98. DOI ScienceOn |
25 | Araki K, Yamashita T, Reddy N, et al (2010). Molecular disruption of NBS1 with targeted gene delivery enhances chemosensitisation in head and neck cancer. Br J Cancer, 103, 1822-30. DOI |
26 | Chen YC (2005). Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-Kinase/Akt. J Biol Chem, 280, 32505-11. DOI |
27 | Choudhury A, Elliott F, Iles MM, et al (2008). Analysis of variants in DNA damage signalling genes in bladder cancer. BMC Med Genetics, 9, 69. |
28 | Dumon-Jones V, Frappart PO, Tong WM, et al (2003). Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation-induced tumorigenesis. Cancer Res, 63, 7263-9. |
29 | Eisenhauer EA, Therasse P, Bogaerts J, et al (2009). New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer, 45, 228-47. DOI ScienceOn |
30 | Futaki M, Liu JM (2001). Chromosomal breakage syndromes and the BRCA1 genome surveillance complex. Trends Mol Med, 7, 560-5. DOI |
31 | Hsu DS, Chang SY, Liu CJ, et al (2010). Identification of increased NBS1 expression as a prognostic marker of squamous cell carcinoma of the oral cavity. Cancer Sci, 101, 1029-37. DOI |
32 | Hsu HM, Wang HC, Chen ST, et al (2007). Breast cancer risk is associated with the genes encoding the DNA double-strand break repair Mre11/Rad50/Nbs1 complex. Cancer Epidemiol Biomarkers Prev, 16, 2024-32. DOI |
33 | Kelly K, Crowley J, Bunn PA Jr, et al (2001). Randomized phase III trial of paclitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced non-- small-cell lung cancer: a Southwest Oncology Group trial. J Clin Oncol, 19, 3210-8. DOI |
34 | Park SL, Bastani D, Goldstein BY, et al (2010). Associations between NBS1 polymorphisms, haplotypes and smokingrelated cancers. Carcinogenesis, 31, 1264-71. DOI |
35 | Perez RP (1998). Cellular and molecular determinants of cisplatin resistance. Eur J Cancer, 34, 1535-42. DOI |
36 | Ryk C, Kumar R, Thirumaran R, Hou S (2006). Polymorphisms in the DNA repair genes XRCC1, APEX1, XRCC3 and NBS1, and the risk for lung cancer in never- and eversmokers. Lung Cancer, 54, 285-92. DOI |
37 | Scagliotti GV, De Marinis F, Rinaldi M, et al (2002). Phase III randomized trial comparing three platinum-based doublets in advanced non-small-cell lung cancer. J Clin Oncol, 20, 4285-91. DOI ScienceOn |
38 | Schiller JH, Harrington D, Belani CP, et al (2002). Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med, 346, 92-8. DOI ScienceOn |
39 | Schuetz JM, MacArthur AC, Leach S, et al (2009). Genetic variation in the NBS1, MRE11, RAD50 and BLM genes and susceptibility to non-Hodgkin lymphoma. BMC Med Genetics, 10, 117. DOI |
40 | Siddik ZH (2003). Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene, 22, 7265-79. DOI ScienceOn |
41 | Spiro SG, Silvestri GA (2005). The treatment of advanced nonsmall cell lung cancer. Curr Opin Pulm Med, 11, 287-91. DOI |
42 | Stern MC, Lin J, Figueroa JD, et al (2009). Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer. Cancer Res, 69, 6857-64. DOI |
43 | Tauchi H (2000). Positional cloning and functional analysis of the gene responsible for Nijmegen breakage syndrome, NBS1. J Radiat Res, 41, 9-17. |
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