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http://dx.doi.org/10.7314/APJCP.2012.13.1.131

ABO Blood Group and Risk of Pancreatic Cancer in a Turkish Population in Western Blacksea Region  

Engin, Huseyin (Department of Oncology, Zonguldak Karaelmas University School of Medicine)
Bilir, Cemil (Department of Oncology, Zonguldak Karaelmas University School of Medicine)
Ustun, Hasan (Department of Oncology, Zonguldak Karaelmas University School of Medicine)
Gokmen, Ayla (Department of Hematology, Zonguldak Karaelmas University School of Medicine)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.13, no.1, 2012 , pp. 131-133 More about this Journal
Abstract
Background: We aimed to investigate the relationship between blood groups and pancreatic cancer in a Turkish population in Western Blacksea region. Methods: This is a retrospective study. Zonguldak Karaelmas University outpatient oncology clinic records were screened for the period between 2004 and 2011. Results: The median age of patients were 56 (${\pm}16$) and 132 of 633 study population had pancreatic cancer. Pancreatic cancer patients had significantly higher rates of blood group A compared to controls (OR 1.8, 95%CI, p 0.005). Rates of blood group AB was significantly lower than the control group (OR 0.37, 95% CI, p 0.04). The median survival (IR) time in subjects having the blood groups A, B, AB and O were 7.0 (1-28), 7.0 (2-38), 10 (2-36) and 9.0 (2-48) months respectively; the blood group 0 had significantly higher overall survival (OS) compared to the non-0 groups (p 0.04). Conclusions: Pancreatic cancer patients had more common blood group A in our population. Moreover, blood group AB appeared to be a protective factor against pancreatic cancer in our population. Blood group 0 had a significantly longer survival compared to non-0, regardless of prognostic factors.
Keywords
Blood group; pancreatic cancer; survival; Turkey;
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