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http://dx.doi.org/10.7472/jksii.2014.15.4.21

Evaluation of Usefulness of the Protein Drug Feature Information Filed  

Byeon, Jaehee (Dept. of Stereoscopic Media, Korean German Institute of Technology)
Choi, Yoo-Joo (Dept. of Newmedia, Korean German Institute of Technology)
Lee, Ju-Hwan (Dept. of Newmedia, Korean German Institute of Technology)
Suh, Jung-Keun (Dept. of Newmedia, Korean German Institute of Technology)
Publication Information
Journal of Internet Computing and Services / v.15, no.4, 2014 , pp. 21-31 More about this Journal
Abstract
As the protein drug industry is growing, protein informations are indispensable for the protein drug development. NCBI and PDB in the U.S., the EMBL in Europe and the DDBJ in Japan are the representative centers for bio information and each center provides specific data for protein information. To obtain specific protein information, users are to be collect them from the service sites of each center and then combine or analyze for their purpose. To facilitate the accessibility to bio data, various R&D activities are running for development of diverse web services relevant to bio data in major data centers or small-scale projects. With the recognition of protein information as pivotal for the protein drug development, DrugBank in Canada, GDSC in the U.S. start to provide integrated informations between drugs and proteins. However, those service does not meet users' demands due to lack of diversity. In Korea, infra structures for bioinformatics are limited and the current services for protein drug information are providing only basic information of the drug including distribution data. This is a pilot study to construct a specialized service for protein drug information in Korean style breaking through the limitations of current services. This study proposed new fields for protein characterization information which had not been provided by current services and evaluated their effectiveness and usability by comparing them to the existing fields with expert survey. As a result, the newly proposed fields for protein characterization have been proven to be useful data fields for the service of protein drug information.
Keywords
Bioinformatics; Protein Drug; Characterization;
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