Fucoidan Upregulates Chemotactic Activity of Porcine Peripheral Blood Polymorphonuclear Cells to Interleukin-8 by PI3K Activation |
Kang, Song-Ai
(Department of Veterinary Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University)
Ahn, Changhwan (Department of Veterinary Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University) Kang, Byeong-Teck (Department of Veterinary Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University) Kang, Ji-Houn (Department of Veterinary Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University) Jeung, Eui-Bae (Department of Veterinary Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University) Yang, Mhan-Pyo (Department of Veterinary Medicine, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University) |
1 | Matsubara K, Matsuura Y, Bacic A, Liao M, Hori K, Miyazawa K. Anticoagulant properties of a sulfated galactan preparation from a marine green alga, Codium cylindricum. Int J Biol Macromol 2001; 28: 395-399. DOI |
2 | Nathan C. Neutrophils and immunity: challenges and opportunities. Nat Rev Immunol 2006; 6: 173-182. DOI |
3 | Oudit GY, Penninger JM. Cardiac regulation by phosphoinositide 3-kinases and PTEN. Cardiovasc Res 2009; 82: 250-260 |
4 | Pereira MA, Sannomiya P, Leme JG. Inhibition of leukocyte chemotaxis by factor in alloxan-induced diabetic rat plasma. Diabetes 1987; 36: 1307-1314. DOI |
5 | Postma M, Bosgraaf L, Loovers HM, Van Haastert PJ. Chemotaxis: signalling modules join hands at front and tail. EMBO Rep 2004; 5: 35-40. DOI |
6 | Rameh LE, Cantley LC. The role of phosphoinositide 3-kinase lipid products in cell function. J Biol Chem 1999; 274: 8347-8350. DOI |
7 | Westphal M, Jungbluth A, Heidecker M, Muhlbauer B, Heizer C, Schwartz JM, Marriott G, Gerisch G. Microfilament dynamics during cell movement and chemotaxis monitored using a GFP-actin fusion protein. Curr Biol 1997; 7: 176-183. DOI |
8 | Xu J, Wang F, Van Keymeulen A, Herzmark P, Straight A, Kelly K, Takuwa Y, Sugimoto N, Mitchison T, Bourne HR. Divergent signals and cytoskeletal assemblies regulate selforganizing polarity in neutrophils. Cell 2003; 114: 201-214. DOI |
9 | Sasaki T, Irie-Sasaki J, Jones RG, Oliveira-dos-Santos AJ, Stanford WL, Bolon B, Wakeham A, Itie A, Bouchard D, Kozieradzki I, Joza N, Mak TW, Ohashi PS, Suzuki A, Penninger JM. Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration. Science 2000; 287: 1040-1046. DOI |
10 | Sadhu C, Masinovsky B, Dick K, Sowell CG, Staunton DE. Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement. J Immunol 2003; 170: 2647-2654. DOI |
11 | Son SM, Kang JH, Lee GS, Jeung EB, Yang MP. Induction of interleukin-8 expression in porcine peripheral blood mononuclear cells by trans10-cis12 conjugated linoleic acid. Vet Immunol Immunopathol 2006; 112: 284-289. DOI |
12 | Stephens L, Ellson C, Hawkins P. Roles of PI3Ks in leukocyte chemotaxis and phagocytosis. Curr Opin Cell Biol 2002; 14: 203-213. DOI |
13 | Blazquez S, Guigon G, Weber C, Syan S, Sismeiro O, Coppee JY, Labruyere E, Guillen N. Chemotaxis of Entamoeba histolytica towards the pro-inflammatory cytokine TNF is based on PI3K signalling, cytoskeleton reorganization and the galactose/N-acetylgalactosamine lectin activity. Cell Microbiol 2008; 10: 1676-1686. DOI |
14 | Ali H, Haribabu B, Richardson RM, Snyderman R. Mechanisms of inflammation and leukocyte activation. Med Clin North Am 1997; 81: 1-28. DOI |
15 | Arraes SM, Freitas MS, da Silva SV, de Paula Neto HA, Alves-Filho JC, Auxiliadora Martins M, Basile-Filho A, Tavares-Murta BM, Barja-Fidalgo C, Cunha FQ. Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation. Blood 2006; 108: 2906-2913. DOI |
16 | Backstrom L, Hoefling DC, Morkoc AC, Cowart RP. Effect of atrophic rhinitis on growth rate in Illinois swine herds. J Am Vet Med Assoc 1985; 187: 712-715. |
17 | Bourne HR, Weiner O. A chemical compass. Nature 2002;419: 21. DOI |
18 | Hirsch E, Katanaev VL, Garlanda C, Azzolino O, Pirola L, Silengo L, Sozzani S, Mantovani A, Altruda F, Wymann MP. Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science 2000; 287: 1049-1053. DOI |
19 | Jeon CJ, Kim SH, Kim SS, Kang JH, Yang MP. Fucoidan upregulates chemotactic activity of canine peripheral blood polymorphonuclear cells through interleukin-8 from peripheral blood mononuclear cells in vitro. J Vet Clin 2012; 29: 207-212. |
20 | Vanhaesebroeck B, Jones GE, Allen WE, Zicha D, Hooshmand-Rad R, Sawyer C, Wells C, Waterfield MD, Ridley AJ. Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages. Nat Cell Biol 1999; 1: 69-71. DOI |
21 | Vanhaesebroeck B, Leevers SJ, Ahmadi K, Timms J, Katso R, Driscoll PC, Woscholski R, Parker PJ, Waterfield MD. Synthesis and function of 3-phosphorylated inositol lipids. Annu Rev Biochem 2001; 70: 535-602. DOI |
22 | Weiner OD, Neilsen PO, Prestwich GD, Kirschner MW, Cantley LC, Bourne HR. A PtdInsP(3)- and Rho GTPasemediated positive feedback loop regulates neutrophil polarity. Nat Cell Biol 2002; 4: 509-513. DOI |
23 | Kim SH, Kang JH, Yang MP. Fucoidan directly regulates the chemotaxis of canine peripheral blood polymorphonuclear cells by activating F-actin polymerization. Vet Immunol Immunopathol 2013; 151: 124-131. DOI |
24 | Katso R, Okkenhaug K, Ahmadi K, White S, Timms J, Waterfield MD. Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer. Annu Rev Cell Dev Biol 2001; 17: 615-675. DOI |
25 | Kawashima T, Murakami K, Nishimura I, Nakano T, Obata A. A sulfated polysaccharide, fucoidan, enhances the immunomodulatory effects of lactic acid bacteria. Int J Mol Med 2012; 29: 447-453. |
26 | Kim H, Lee A, Jung WK, Jeon TJ. Effects of fucoidan on cell morphology and migration in osteoblasts. Food Sci Biotechnol 2015; 24: 699-704. DOI |
27 |
Kim SH, Kang JH, Yang MP. Fucoidan increases phagocytic capacity and oxidative burst activity of canine peripheral blood polymorphonuclear cells through TNF- |
28 | Chung CY, Funamoto S, Firtel RA. Signaling pathways controlling cell polarity and chemotaxis. Trends Biochem Sci 2001; 26: 557-566. DOI |
29 | Cho TM, Kim WJ, Moon SK. Akt signaling is involved in fucoidan-induced inhibition of growth and migration of human bladder cancer cells. Food Chem Toxicol 2014; 64: 344-352. DOI |
30 | Chodniewicz D, Zhelev DV. Chemoattractant receptorstimulated F-actin polymerization in the human neutrophil is signaled by 2 distinct pathways. Blood 2003; 101: 1181-1184. DOI |
31 | Dharmawardhane S, Brownson D, Lennartz M, Bokoch GM. Localization of p21-activated kinase 1 (PAK1) to pseudopodia, membrane ruffles, and phagocytic cups in activated human neutrophils. J Leukoc Biol 1999; 66: 521-527. DOI |
32 |
Ferguson GJ, Milne L, Kulkarni S, Sasaki T, Walker S, Andrews S, Crabbe T, Finan P, Jones G, Jackson S, Camps M, Rommel C, Wymann M, Hirsch E, Hawkins P, Stephens L. PI (3) |
33 | Fry MJ. Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?. Breast Cancer Res 2001; 3:304-312. DOI |
34 | Hayashi K, Nakano T, Hashimoto M, Kanekiyo K, Hayashi T. Defensive effects of a fucoidan from brown alga Undaria pinnatifida against herpes simplex virus infection. Int Immunopharmacol 2008; 8: 109-116. DOI |
35 | Maruyama H, Tamauchi H, Iizuka M, Nakano T. The role of NK cells in antitumor activity of dietary fucoidan from Undaria pinnatifida sporophylls (Mekabu). Planta Med 2006; 72: 1415-1417. DOI |
36 | Kolsch V, Seher T, Fernandez-Ballester G. J, Serrano L, Leptin M. Control of Drosophila gastrulation by apical localization of adherens junctions and RhoGEF2. Science 2007; 315: 384-386. DOI |
37 | Lee H, Kim JS, Kim E. Fucoidan from seaweed Fucus vesiculosus inhibits migration and invasion of human lung cancer cell via PI3K-Akt-mTOR pathways. PLoS One 2012; 7: e50624. DOI |
38 | Li W, Liu G, Chou IN, Kagan HM. Hydrogen peroxidemediated, lysyl oxidase-dependent chemotaxis of vascular smooth muscle cells. J Cell Biochem 2000; 78: 550-557. DOI |
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