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http://dx.doi.org/10.17555/jvc.2017.02.34.1.18

Efficacy of Half Dose House Dust Mites-Specific Immunotherapy on Canine Atopic Dermatitis  

Park, Jeong-Ho (College of Veterinary Medicine & Research Institute of Veterinary Medicine, Chungnam National University)
Lee, Wang-Hui (College of Veterinary Medicine & Research Institute of Veterinary Medicine, Chungnam National University)
Park, Seong-Jun (College of Veterinary Medicine & Research Institute of Veterinary Medicine, Chungnam National University)
Publication Information
Journal of Veterinary Clinics / v.34, no.1, 2017 , pp. 18-22 More about this Journal
Abstract
The aim of this study was to prove that the hypothesis of half dose (HD) allergen-specific immunotherapy (ASIT) in the treatment of canine atopic dermatitis (CAD) would result in a similar success rate compared to the standard dose (SD) ASIT. Clinical signs were evaluated using a third version of the Canine Atopic Dermatitis Extent and Severity Index (CADESI-03) prior to ASIT (day 0), at the end of induction (day 43), and at three month afterwards (day 90). Of the 18 atopic dogs, 12 dogs (SD group: 6; HD group: 6) had a good - excellent response to the house dust mites-specific immunotherapy. The efficacies of ASIT were 66.6% in both groups. The grades of reduction rate CADESI-03 were not different between two groups. Therefore, half dose protocol of house dust mites-specific immunotherapy is an effective and efficient method to treat CAD.
Keywords
dog; atopic dermatitis; house dust mite; half-dose; immunotherapy;
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