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http://dx.doi.org/10.17555/jvc.2015.08.32.4.352

Preservation through Cloning of Superior Canine Scent Detection Ability for Cancer Screening  

Kim, Min-Jung (College of Veterinary Medicine, Seoul National University)
Park, Jung-Eun (Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health)
Oh, Hyun-Ju (College of Veterinary Medicine, Seoul National University)
Hong, So-Gun (Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health)
Kang, Jung-Taek (GIBLUE Biotechnology Research Institute)
Rhim, Sang-Hyun (K-Stem Cell)
Lee, Dong-Won (K-Stem Cell)
Ra, Jung-Chan (K-Stem Cell)
Lee, yeong-Chun (College of Veterinary Medicine, Seoul National University)
Publication Information
Journal of Veterinary Clinics / v.32, no.4, 2015 , pp. 352-355 More about this Journal
Abstract
This study was conducted to ascertain whether the scent detection ability of a donor dog having extraordinary talent in cancer detection can be conserved through cloning. A specially trained dog for colorectal cancer detection was cloned, and she was trained and tested to detect breast cancers using breath samples collected from patients and healthy volunteers. Scent detection sensitivity of the clone was 93.3% and specificity was 99.5%, similar with those of donor (91% and 99%). Furthermore, the clone successfully detected early stage of breast cancers. Therefore, superior canine scent detection ability for cancer screening could be preserved through cloning.
Keywords
canine scent detection; cloning; dogs; breast cancers; diagnosis;
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