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Polycystic Kidney Disease in the Adult Female Pygmy Hippopotamus (Choeropsis liberiensis)  

Eo, Kyung Yeon (Seoul Zoo)
Lee, Myung Hee (Seoul Zoo)
Jeong, Yeong Mok (Seoul Zoo)
Yeo, Yong Gu (Seoul Zoo)
Lee, Hyun Ho (Seoul Zoo)
Moon, Kyung Chul (Department of Pathology and Kidney Research Institute, Medical Research Center, Seoul National University College of Medicine)
Kwon, Oh-Deog (College of Veterinary Medicine, Kyungpook National University)
Publication Information
Journal of Veterinary Clinics / v.31, no.5, 2014 , pp. 466-468 More about this Journal
Abstract
Polycystic kidney disease (PKD) is characterized by multiple cysts within the renal parenchyma and is a common heritable disease in humans, dogs, and cats. However, a few cases of PKD have been described in captive pygmy hippopotamuses. Bilateral PKD was observed in a 33-year-old, 198-kg female pygmy hippopotamus during its necropsy in Seoul Zoo on 15 January 2013. The diagnosis of PKD was confirmed by gross findings and histopathological examination. One kidney was slightly enlarged, and the lower portion of other kidney contained a large cyst filled with light yellow, watery fluid. Both kidneys had numerous, variably sized fluid-filled cysts of 2 to 20 mm in diameter. Considerable portions of the renal cortex and medulla were replaced by cysts. Microscopic inspection showed that the cysts were lined with low cuboidal to flat epithelial cells. The present case report of PKD in a pygmy hippopotamus is the first in Korea.
Keywords
Polycystic kidney disease; pygmy hippopotamus; Choeropsis liberiensis;
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