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Spinal Syringomyelia Secondary to an Intracranial Microcystic Meningioma in a Dog  

Won, Sangcheol (Yeonhee Animal Clinic)
Kim, Jae-Hoon (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)
Publication Information
Journal of Veterinary Clinics / v.31, no.5, 2014 , pp. 439-444 More about this Journal
Abstract
A 5-year-old, 2.7 kg female maltese dog was presented a local veterinary clinic with one week history of hindlimb lameness associated with patellar luxation. Reduction of bilateral medial patellar luxation was operated using trochlear resection and lateral reinforcement technique. Three weeks after the surgery, the dog showed bending spine with pain in thoracic and lumbar region, continuous ataxia and intermittent convulsion. Magnetic resonance imaging scanning revealed a hyperintense mass in right frontal lobe of brain and abnormal cavitation from cervical cord to third lumbar cord. Histopathologically, neoplasm in brain composed of meningothelial cells showed loosely reticular or lace-like morphology with numerous extracellular cystic spaces of variable size and shape. Neoplastic cells were positive for vimentin and negative for neuron specific enolase and glial fibrillary acidic protein. Irregular shaped enlarge central canal-like cavity was existed in cervical and lumbar cords. In our best knowledge, this report described the clinical findings, imaging and histopathologic characteristics of unusual intracranial microcystic meningioma with secondary syringomyelia in a dog.
Keywords
convulsion; dog; magnetic resonance imaging; microcystic meningioma; syringomyelia;
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1 da Costa RC, Parent JM, Poma R, Duque MC. Cervical syringohydromyelia secondary to a brainstem tumor in a dog. J Am Vet Med Assoc 2004; 225: 1061-1064, 1048.   DOI
2 Choi CB, Bae CS, Kim HY. MRI of hydrosyringomyelia combined to hydrocephalus and occipital dysplasia in a dog. J Life Sci 2005; 15: 664-667.   DOI
3 Anegawa S, Hayashi T, Torigoe R, Iwaisako K, Higashioka H. Cerebellopontine angle meningioma causing asymptomatic syringomyelia--case report. Neurol Med Chir (Tokyo) 1997; 37: 624-626.   DOI   ScienceOn
4 Fossum TW. Surgery of the brain. In: Small animal surgery, 3rd ed. St. Luis: Mosby Elsevier. 2007: 1397-1401.
5 Fox B, Muzumdar D, DeMonte F. Resolution of tonsillar herniation and cervical syringomyelia following resection of a large petrous meningioma: case report and review of literature. Skull Base 2005; 15: 89-97.   DOI
6 Itoh T, Nishimura R, Matsunaga S, Kadosawa T, Mochizuki M, Sasaki N. Syringomyelia and hydrocephalus in a dog. J Am Vet Med Assoc 1996; 209: 934-936.
7 Jung DI, Park C, Kang BT, Kim JW, Kim HJ, Lim CY, Jeong SW, Park HM. Acquired cervical syringomyelia secondary to a brainstem meningioma in a maltese dog. J Vet Med Sci 2006; 68: 1235-1238.   DOI
8 Mandrioli L, Panarese S, Cesari A, Mandara MT, Marcato PS, Bettini G. Immunohistochemical expression of h-telomerase reverse transcriptase in canine and feline meningiomas. J Vet Sci 2007; 8: 111-115.   DOI
9 Meuten DJ. Tumors of the nervous system. In: Tumors in domestic animals, 4th ed. Ames: Iowa State Press. 2002: 717-723.
10 Motta L, Mandara MT, Skerritt GC. Canine and feline intracranial meningiomas: an updated review. Vet J 2012; 192: 153-165.   DOI
11 Paek SH, Kim SH, Chang KH, Park CK, Kim JE, Kim DG, Park SH, Jung HW. Microcystic meningiomas: radiological characteristics of 16 cases. Acta Neurochir (Wien) 2005; 147: 965-972.   DOI
12 Patnaik AK, Kay WJ, Hurvitz AI. Intracranial meningioma: a comparative pathologic study of 28 dogs. Vet Pathol 1986; 23: 369-373.   DOI   ScienceOn
13 Platt S, Olby N (Bagley RS). Coma, stupor and behavioural change. In: BSAVA Manual of Canine and Feline Neurology, 3rd ed. Cheltenham: BSAVA. 2004: 113-132.
14 Salvadori C, Pintore MD, Ricci E, Konar M, Tartarelli CL, Gasparinetti N, Cantile C. Microcystic meningioma of the fourth ventricle in a dog. J Vet Med Sci 2011; 73: 367-370.   DOI
15 Wolfe KC, Poma R. Syringomyelia in the Cavalier King Charles spaniel (CKCS) dog. Can Vet J 2010; 51: 95-102.
16 Ramos-Vara JA, Miller MA, Gilbreath E, Patterson JS. Immunohistochemical detection of CD34, E-cadherin, claudin- 1, glucose transporter 1, laminin, and protein gene product 9.5 in 28 canine and 8 feline meningiomas. Vet Pathol 2010; 47: 725-737.   DOI
17 Barnhart KF, Wojcieszyn J, Storts RW. Immunohistochemical staining patterns of canine meningiomas and correlation with published immunophenotypes. Vet Pathol 2002; 39: 311-321.   DOI   ScienceOn
18 Montoliu P, Añor S, Vidal E, Pumarola M. Histological and immunohistochemical study of 30 cases of canine meningioma. J Comp Pathol 2006; 135: 200-207.   DOI   ScienceOn