Browse > Article

Treatment of Lymphocytic Gastritis with Cyclosporine in a Cat  

Lee, Hwajoon (College of Veterinary Medicine, Chungbuk National University)
Park, So-Young (College of Veterinary Medicine, Chungbuk National University)
Ahn, Byeongwoo (College of Veterinary Medicine, Chungbuk National University)
Yang, Mhan-Pyo (College of Veterinary Medicine, Chungbuk National University)
Kang, Ji-Houn (College of Veterinary Medicine, Chungbuk National University)
Publication Information
Journal of Veterinary Clinics / v.31, no.2, 2014 , pp. 108-111 More about this Journal
Abstract
A 7-year-old spayed female domestic shorthair cat was referred for chronic intermittent vomiting. The frequency of vomiting increased recently, and the cat showed anorexia at presentation. There were no remarkable abnormalities on the blood analyses and diagnostic imaging. However, the endoscopic examination revealed focal erosions of the gastric body mucosa, and subsequent multiple biopsies were obtained. Histopathologic examination indicated mild to moderate lymphocytic gastritis. The vomiting was completely disappeared 7 days after the administration with prednisolone (PDS). However, because of side effects caused by the long-term PDS administration, cyclosporine was added on the prescription with tapered dose of PDS. The dog's condition improved with continued cyclosporine treatment, and no further vomiting and anorexia episodes have been noted. This case describes the successful management with administration of cyclosporine in feline lymphocytic gastritis.
Keywords
endoscopy; feline; lymphocytic gastritis; prednisolone;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Zur G, Botero-Anug AM. Severe ulcerative and granulomatous pinnal lesions with granulomatous sebaceous adenitis in unrelated vizslas. J Am Anim Hosp Assoc 2011; 47: 455-460.   DOI   ScienceOn
2 Schiffrin EJ, Blum S. Interactions between the microbiota and the intestinal mucosa. Eur J Clin Nutr 2002; 56: S60-64.   DOI   ScienceOn
3 Scott KD, Zoran DL, Mansell J, Norby B, Willard MD. Utility of endoscopic biopsies of the duodenum and ileum for diagnosis of inflammatory bowel disease and small cell lymphoma in cats. J Vet Intern Med 2011; 25: 1253-1257.   DOI   ScienceOn
4 Simpson KW. Diseases of the Stomach. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine, 7th ed. St. Louis: Elsevier Saunders. 2010: 1515-1526.
5 Benitah N, de Lorimier LP, Gaspar M, Kitchell BE. Chlorambucil-induced myoclonus in a cat with lymphoma. J Am Anim Hosp Assoc 2003; 39: 283-287.   DOI
6 Borel JF, Feurer C, Gubler HU, Stähelin H. Biological effects of cyclosporin A: A new antilymphocytic agent. Agents Actions 1976; 6: 468-475.   DOI   ScienceOn
7 Guilford WG. Idiopathic inflammatory bowel diseases. In: Guilford WG, Center SA, Strombeck DR, Williams DA, Meyer DJ, eds. Strombeck's Small Animal Gastroenterology, 3rd ed. Philadelphia: WB Saunders. 1996; 451-486.
8 Haot J, Hamichi L, Wallez L, Mainguet P. Lymphocytic gastritis: a newly described entity: a retrospective endoscopic and histological study. Gut 1988; 29: 1258-1264.   DOI   ScienceOn
9 Huang-Kornic E. Chronic intermittent vomiting in a cat: a case of chronic lymphocytic-plasmacytic gastritis. Can Vet J 1999; 40: 196-198.
10 Linek M, Boss C, Haemmerling R, Hewicker-Trautwein M, Mecklenburg L. Effects of cyclosporine A on clinical and histologic abnormalities in dogs with sebaceous adenitis. J Am Vet Med Assoc 2005; 226: 59-64.   DOI   ScienceOn
11 Noli C, Toma S. Three cases of immune-mediated adnexal skin disease treated with cyclosporin. Vet Dermatol 2006; 17: 85-92.   DOI   ScienceOn
12 Pohlman LM, Higginbotham ML,Welles EG, Johnson CM. Immunophenotypic and histologic classification of 50 cases of feline gastrointestinal lymphoma. Vet Pathol 2009; 46: 259-268.   DOI   ScienceOn
13 Robson D. Review of the pharmacokinetics, interactions and adverse reactions of cyclosporine in people, dogs and cats. Vet Rec 2003; 152: 739-748.   DOI