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Sublingual Granular Cell Tumor in a Dog  

Park, Jun-Won (College of Veterinary Medicine, Seoul National University)
Jee, Hyang (College of Veterinary Medicine, Seoul National University)
Oh, Won-Seok (NeoDin Veterinary Science Institute)
Kim, Eun-Ok (NeoDin Veterinary Science Institute)
Youn, Sin-Keun (Dr.Youn's Animal Hospital)
Woo, Gye-Hyeong (National Veterinary Research Institute and Quarantine Service)
Kim, Dae-Yong (College of Veterinary Medicine, Seoul National University)
Publication Information
Journal of Veterinary Clinics / v.27, no.4, 2010 , pp. 491-493 More about this Journal
Abstract
Granular cell tumor was described in a 7-year-old male Miniature Pinscher. Sublingual mass was surgically removed and submitted for diagnosis. The mass was about 1.8 cm in diameter, firm, tan, and ulcerated. On histopathology, the mass was unencapsulated and infiltrated adjacent tissue and consisted of nest or sheet of round to polygonal, and occasional spindle-shaped cells. The neoplastic cells contain large amount of eosinophilic granular materials in the cytoplasm. Immunohistochemically, the neoplastic cells were positive to neuron-specific enolase but were negative to S-100. The cytoplasmic eosinophilic granules were positive to PAS but were negative to PTAH methods. Based on these results, the mass was diagnosed as sublingual granular cell tumor. No recurrence or metastasis was noted so far since surgery.
Keywords
granular cell tumor; dog;
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