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Therapeutic Effect of Dioctahedral Smectite on Diarrhea Caused by E. coli and Salmonella in Piglets  

Jung, Won-Chul (Research Institute of Life Sciences, College of Veterinary Medicine, Gyeongsang National University)
Cha, Chun-Nam (Engineering Research Institute, Department of Industrial Systems Engineering, Gyeongsang National University)
Kim, Young-Il (Pharmaceutical Engineering, Konyang University)
Lee, Yeo-Eun (Department of Environmental Health, Graduate School of Public Health, Gyeongsang National University)
Yoo, Chang-Yeul (Department of Computer Information, Gyeongnam Provincial Namhae College)
Kim, Suk (Research Institute of Life Sciences, College of Veterinary Medicine, Gyeongsang National University)
Lee, Hu-Jang (Research Institute of Life Sciences, College of Veterinary Medicine, Gyeongsang National University)
Publication Information
Journal of Veterinary Clinics / v.27, no.4, 2010 , pp. 378-381 More about this Journal
Abstract
The objectives in the present study were to evaluate the therapeutic effect of dioctahedral smectite (smectite) against piglet diarrhea caused by E. coli and Salmonella. Of this study, twenty piglets (body weight, $6.60{\pm}0.34\;kg$) with diarrhea were used to estimate the efficacy of smectite on piglet diarrhea with 20% smectite suspension in PBS. Pigs were administered with 1 ml smectite suspension three times a day after feeding, and fecal samples were collected at the gate of treatment and on 1st, 2nd, 3rd, and 4th day after administration. Changes in body weight, diarrhea index, and shedding of E. coli and Salmonella were monitored during the experimental period. The group treated with smectite reduced diarrhea index (p < 0.01), and increased body weight compared to control group. In the treated group, the number of E. coli and Salmonella was significantly decreased compared to each control group (p < 0.01). From results of the present study, 20% smectite suspension had therapeutic effect on diarrhea caused by E. coli and Salmonella in piglets.
Keywords
dioctahedral smectite; piglet diarrhea; E. coli; Salmonella;
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Times Cited By KSCI : 7  (Citation Analysis)
Times Cited By SCOPUS : 2
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