Medetomidine Sedation and Its Antagonism by Yohimbine in Dogs |
Heo, Keong-Hee
(College of Veterinary Medicine, Research Center for Transgenic Cloned Pigs, Chungnam National University)
Lee, Jae-Yeon (College of Veterinary Medicine, Research Center for Transgenic Cloned Pigs, Chungnam National University) Choi, Kyeong-Ha (College of Veterinary Medicine, Research Center for Transgenic Cloned Pigs, Chungnam National University) Cho, Jin-Haeng (College of Veterinary Medicine, Research Center for Transgenic Cloned Pigs, Chungnam National University) Park, Chang-Sik (Division of Animal Science & Resources, Research Center for Transgenic Cloned Pigs, Chungnam National University) Kim, Myung-Cheol (College of Veterinary Medicine, Research Center for Transgenic Cloned Pigs, Chungnam National University) |
1 | Salonen JS. Phamacokinetics of medetomidine. Acta Vet Scand Suppl 1989; 85: 49-54. |
2 | Ueyema Y, Waselau AC, Wiese AJ, Muir WW. Anesthetic and cardiopulmonary effects of intramuscular morphine, medetomidine, ketamine injection in dogs. Vet Anaesth Analg 2008; 35: 480-487. DOI ScienceOn |
3 | Hsu, W.H., Schaffer D.D, and Pineda, M.H. Yohimbine increases plasma insulin concentrations of dog. Exp Biol Med 1987; 184: 345-349. |
4 | Lemke, KA. Anticholinergics and sedatives. In: Veterinary anesthesia and analgesia, 4th ed. Ames: Blackwell Publishing. 2007: 217-222. |
5 | Maze M, Tranquilli W. Alpha 2 adrenoceptor agonists: Defining the role in clinical anesthesia. Anesthesiol 1991; 74: 581-605. DOI ScienceOn |
6 | Plumb DC. Veterinary Drug Handbook, 5th ed. Ames: Iowa State University Press. 2002: 690-691. |
7 | Plumb DC. Plumb's Veterinary Drug Handbook, 6th ed. Ames: Blackwell Publishing. 2008: 690-691. |
8 | Gross ME, Tranquili WJ. Use of alpha-2 adrenergic receptor antagonists. J Am Vet Med Assoc 1989; 195: 378-381. |
9 | Hatch RC, Booth NH, Clark JD, Crawford LM, Kitzman JV, Wallner B. Antagonism of xylazine sedation in dogs by 4-aminopyridine and yohimbine. Am J Vet Res 1982; 43: 1009-1014. |
10 | Hsu WH, Lu ZX. Effect of yohimbine on xylazine-ketamine anesthesia in cats. J Am Vet Med Assoc 1984; 185: 886-888. |
11 | Hsu WH, Rong YF, Hembrough FB. The effects of jingsongling, a xylazine analog, on mean arterial blood pressure and heart rate in dogs--influences of yohimbine, tolazoline, prazosin, and atropine. J Vet Pharmacol Ther 1989; 12: 283. DOI ScienceOn |
12 | Andrejak, M., Ward, M., and Schmitt, H. Cardiovascular effects of yohimbine in anesthesia dogs. Eur J Pharmacol 1983; 94: 219-228. DOI ScienceOn |
13 | Ambrisko TD, Hikasa Y. The antagonistic effects of atipamezole and yohimbine on stress-related neurohormonal and metabolic responses induced by medetomidine in dogs. Can J Vet Res 2003; 67: 64-67. |