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Application of Silver Ion for Clinical Mastitis in Holstein Cows  

Seol, Jae-Won (Center for Healthcare Technology Development, Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University)
Hur, Tai-Young (National Institute of Animal Science, Rural Development Administration)
Jung, Young-Hun (National Institute of Animal Science, Rural Development Administration)
Park, Sang-Youel (Center for Healthcare Technology Development, Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University)
Kang, Seog-Jin (National Institute of Animal Science, Rural Development Administration)
Publication Information
Journal of Veterinary Clinics / v.27, no.3, 2010 , pp. 246-251 More about this Journal
Abstract
Mastitis is an inflammation of the mammary gland that develops as a response to pathogenic microorganisms. Somatic cell count (SCC) and bacteriological analysis are the most accepted tools to determine udder health. This study evaluated the effects of intra-mammary gland infusion of silver ion against clinical mastitis in Holstein cows. Silver ion (20 ${\mu}g$/ml) was infused through the intra-mammary gland in quarters having clinical mastitis and milk was collected to determine SCC, and levels of lactoferrin and bovine serum albumin (BSA). Silver ion infusion decreased udder inflammation, firmness and swelling, and reduced clots, BSA, lactoferrin and SCC in milk. However, milk yield and circulating blood cells remained unchanged. The silver ion-mediated reductions of BSA and SCC indicate reduced inflammation and bacterial activity in silver ion-treated mammary glands in Holsteins with mastitis, which may be exploited in a curative strategy.
Keywords
Clinical mastitis; somatic cell count; lactoferrin; silver ion; bovine serum albumin;
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