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Enteritis Caused by Type A Clostridium perfringens Producing $\alpha$-Toxin in a Dog  

Han, Jae-Ik (Veterinary Laboratory Medicine, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University)
Jang, Hye-Jin (Veterinary Laboratory Medicine, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University)
Cheon, Haeng-Bok (Veterinary Radiology, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University)
Kim, Ji-Hye (Veterinary Surgery, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University)
Kim, Gon-Hyung (Veterinary Surgery, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University)
Chang, Dong-Woo (Veterinary Radiology, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University)
Na, Ki-Jeong (Veterinary Laboratory Medicine, Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University)
Publication Information
Journal of Veterinary Clinics / v.27, no.2, 2010 , pp. 190-193 More about this Journal
Abstract
A 6-year-old, female, Siberian husky was referred with mucous diarrhea. On fecal examination, numerous clustered and individual large epithelial cells and rod-shaped, spore-forming bacteria were examined. By bacterial culture and molecular typing, the bacteria was identified as Clostridium perfringens (C. perfringens), and by toxin analysis of C. perfringens, production of $\alpha$-toxin was confirmed. Based on these results, the dog was diagnosed as enteritis caused by C. perfringens producing $\alpha$-toxin, and was treated with amoxicillin/clavulanate. After 1 week, the diarrhea was disappeared and no spore-forming bacteria were examined on fecal examination. This report shows that the rapid and exact diagnosis keeps a effective treatment for enteritis caused by C. perfringens producing $\alpha$-toxin in dogs.
Keywords
dog; enteritis; Clostridium perfringens; $\alpha$-Toxin; amoxicillin/clavulanate;
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