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Hepatocellular Carcinoma in a Cocker Spaniel Dog with Hypoglycemia  

Kang, Min-Hee (BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Deseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Yoo, Jong-Hyun (BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Deseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Park, Hee-Myung (BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Deseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Publication Information
Journal of Veterinary Clinics / v.27, no.2, 2010 , pp. 175-178 More about this Journal
Abstract
A 5-year-old male Cocker spaniel was presented with an abrupt seizure episode. The dog was moderately dehydrated, hypersalivation and loss of consciousness at the presentation. Tentative diagnosis was made through history taking, clinical signs, physical examination, neurologic examination, basic laboratory examinations, radiological examination and cytologic examination. In addition, serum alpha-fetoprotein (AFP) value was measured to diagnose in this case. The serum AFP concentration was marked elevated (1513.5 ng/ml). The patient was suspected as HCC and medical therapy was initiated to control hypoglycemic-associated seizure. However, the dog was euthanized because of the owner's request. It was diagnosed as hepatocellular carcinoma (HCC) based on the histopathologic examination. This case indicates that AFP measurement might be valuable to diagnose HCC in dogs.
Keywords
alpha fetoprotein; dog; hepatocellular carcinoma; hypoglycemia;
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