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Cytologic Aspect of Keratoacanthoma with Granulomatous Inflammation in a Dog  

Ji, Hyang (Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University)
Kim, Dae-Yong (Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University)
Ji, Dong-Bum (Ji-Dong Bum Animal Hospital)
Choi, Ul-Soo (Department of Veterinary Clinical Pathology, College of Veterinary Medicine, Chonbuk National University)
Publication Information
Journal of Veterinary Clinics / v.26, no.6, 2009 , pp. 616-618 More about this Journal
Abstract
A 5-year-old Pekinese dog was presented for evaluation of a back mass of 1 year duration. Fine needle aspiration cytology of the mass revealed numerous keratinocytes, and a lesser number of multinucleated giant cells along with a low number of spindle cells, which were suggestive of epidermal cyst or hair follicle tumor with secondary granulomatous inflammation. The mass was surgically removed and examined histologically. Microscopically there was partially encapsulated well-demarcated nodule in deep dermis and subcutis. The nodule consisted of central cyst and secondary cysts that were lined by a single or multiple layers of basaloid cells and squamous epitheliums with central laminated keratin. Multifocal aggregation of numerous macrophages and multinucleated giant cells were present. The final diagnosis was keratoacanthoma with granulomatous inflammation. The mass did not recur 5 months after surgery.
Keywords
Keratinocyte; multinucleated giant cell; keratoacanthoma; cytology; dog;
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