Browse > Article

Computed Tomographic Assessment of Experimentally Induced Legg-Calve-Prethes Disease in Dogs  

Bae, Sun-Hee (College of Veterinary Medicine, Kyungpook National University)
Seong, Yun-Sang (College of Veterinary Medicine, Kyungpook National University)
Eom, Ki-Dong (College of Veterinary Medicine, Konkuk University)
Kim, Jae-Hoon (College of Veterinary Medicine, Cheju National University)
Jang, Kwang-Ho (College of Veterinary Medicine, Kyungpook National University)
Publication Information
Journal of Veterinary Clinics / v.25, no.1, 2008 , pp. 9-14 More about this Journal
Abstract
This purpose of this study was to describe and compare the radiographic and computed tomographic(CT) appearance of the experimentally induced Legg-Calve-Perthes Disease(LCPD) in dogs. LCPD was experimentally induced at the left femoral head in 7 litters of a dog. The lesions were evaluated with radiography, CT, and contrast CT every week from day 7 to day 70 after operation. Histopathologic examination was performed on 92th day after operation. Every images were evaluated according to the staging system of the osteonecrosis published by Association Research of Circulation Osseous in 1997 and the scoring(0-4). On CT scan, diffuse porotic lesion and focal sclerotic lesion were detected on day 14 and on day 21 after operation, respectively. Subchondral fracture, articular collapse and crescent sign with decreased attenuation were shown on day 28 after operation for the first time and no change of the sign were detected from operation day 9 to day 70 after operation. Focal porotic lesion and irregular radiopacity of femoral head were detected on day $41{\pm}7.48$ and on day $51{\pm}5.29$ after operation respectively on radiographs. In scoring evaluation, 2.00 was scored on day 14 after operation on CT scan, on day 56 after operation on radiographs, respectively This study has shown that CT is more suitable for early diagnosis of LCPB and has superior sensitivity than radiography. Also, CT has been expected to be important for staging and treatment of LCPD.
Keywords
Legg-Calve-Perthes Disease(LCPD); computed tomography(CT); radiography; dog;
Citations & Related Records

Times Cited By SCOPUS : 0
연도 인용수 순위
  • Reference
1 Resnick D, Sweet DE, Madewell JE. Osteonecrosis and Osteochondrosis. In: Bone and Joint Imaging, 3rd ed. Philadelphia: WB Saunders. 2004: 1067-1107
2 Steinberg ME, Hayken GD, Steinberg DR. A quantitative system for staging avascular necrosis. J Bone Joint Surg Br. 1995; 77-B: 34-41   DOI
3 Thrall DE. Disease of the immature skeleton In: Textbook of veterinary diagnostic radiology, 4th ed. Philadelphia: WB. Saunders. 2002: 149
4 이승진, 지동범, 박세일, 김인섭, 박희주, 김희천, 김도영. 대퇴관절. 소동물정형외과. 서울: 지성출판사. 2001: 457-458
5 Kaderly RE, Anderson BG, Anderson WD. Intracapsular and intraosseous vascular supply to the mature dog's coxofemoral joint. Am J Vet Res 1983; 44: 1805-1812
6 Stulbulg BN. Editorial Comment. Clin Orthp Relat Res. 1997; 334: 2-5
7 Magid D, Fishman EK, Scott WW, Brooker AF, Arnorld WP, Lennox DW, Siegelman SS. Femoral head avascular necrosis: CT assessment with multiplanar reconstruction. Radiology 1985; 157: 751-756   DOI
8 Johnson KA, Watson A.D.J. Skeletal Disease. In: Textbook of veterinary internal medicine, 6th ed. Philadelphia: Elsevier Saunders. 2005: 1980-1981
9 Stevens K, Tao C, Lee SU, Salem N, Vandevenee J, Cheng C, Neumann G, Opran AV, Lang P. Subchodral fracture in osteonecrosis of the femoral head: Comparison of radiography, CT, and MR Imaging. Am J Roentgenol. 2003; 180: 363-368   DOI   ScienceOn
10 Lang P, Genant HK, Jergesen HE, Murray WR, Imaging of the hip joint: Computed tomography versus magnetic resonance imaging. Clin Orthop Relat Res. 1992; 74: 135-1535
11 Nadel SN, Debatin JF, Richardson WJ, Hedlund LW, Senft C, Rizk WS, Malizos KN, Stahl DL, Martinez S. Detection of acute avascular necrosis of the femoral head in dogs: Dynamic contrast-Enhanced MR imaging vs spin-echo and STIR sequences. Am J Roentgenol. 1992; 159: 1255-1261   DOI   ScienceOn
12 Mitchell MD, Kundel HL, Steinberg ME. Kressel HY, Alavi A, Axel L. Avascular necrosis of the hip: Comparison of MR, CT, and scintigraphy. American J of Roentgenology 1986; 147: 67-71   DOI   ScienceOn
13 Kim HK, Su PH, Qiu YS. Histopathologic changes in growthplate cartilage following ischemic necrosis of the capital femoral epiphysis: An experimental investigation in immature pigs. J Bone Joint Surg Am 2001; 83: 688-697   DOI
14 Cook WE, Smith MM. Perthes Disease. In: Textbook of small animal surgery, 3rd ed. Philadelphia: WB Saunders. 2003: 2260-2264
15 Kaderly RE, Anderson BG. Extraosseous vascular supply to the mature dog's coxofemoral joint. Am J Vet Res 1981; 43: 1208-1214
16 Mitchell DG, Kessel HY, Arger PH, Dalinka M, Spritzer CE, Steinberg ME. Avascular necosis of the femoral head: Morphologic assessment by MR imaging, with CT correlation. Radiology 1986; 161: 739-742   DOI