Browse > Article

A Case of Thromboembolism Occurred in Dog with Immune-Mediated Hemolytic Anemia  

Lee, Chang-Surk (College of Veterinary Medicine, Chungnam National University)
Jun, Hyung-Kyou (College of Veterinary Medicine, Chungnam National University)
Cho, Sung-Nam (College of Veterinary Medicine, Chungnam National University)
Lee, Jung-Youn (Institute of Veterinary Science, Chungnam National University)
Lee, Sang-Eun (Institute of Veterinary Science, Chungnam National University)
Song, Kun-Ho (College of Veterinary Medicine, Chungnam National University)
Lee, Young-Won (College of Veterinary Medicine, Chungnam National University)
Choi, Ho-Jung (College of Veterinary Medicine, Chungnam National University)
Park, Seong-Jun (College of Veterinary Medicine, Chungnam National University)
Cho, Sung-Whan (College of Veterinary Medicine, Chungnam National University)
Publication Information
Journal of Veterinary Clinics / v.24, no.2, 2007 , pp. 255-259 More about this Journal
Abstract
A 6-year-old, intact male, mongrel dog with yellowish urine, anorexia, depression was referred to the Veterinary Medical Teaching Hospital of the Chungnam National university. Immune mediated hemolytic anemia (IMHA) was diagnosed by clinical signs, physical examination, laboratory tests (CBC, serum chemistry, Coombs' test, autoagglutination test and urinalysis) and diagnostic imaging (X-ray and ultrasonography). Clinical signs were improved after combined immune-suppressive therapy (prednisolone and cyclosporine) and prophylactic heparin therapy. A thrombus ($4cm{\times}1cm$) was observed in the right ventricle by autopsy. Combined therapy and supportive care (antithrombolytic agent and acupuncture) were effective in a dog with IMHA.
Keywords
IMHA; thrombus; cyclosporine; acupuncture; dog;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By SCOPUS : 0
연도 인용수 순위
1 Plumb DC. Veterinary drug handbook. 4th ed. Ames; Iowa state press. 2002;713-723
2 Buchanam JW, Bucheler J. Vertebral scale system to measure canine heart size in radiographs. J Am Vet Med Assoc 1995; 206: 194-199
3 Carr AP, Panciera DL, Kidd L. Prognostic factors for mortality and thromboembolism in canine immune-mediated hemolytic anemia: a retrospective study of 72 dogs. J Vet Intern Med 2002; 16: 504-509   DOI
4 Kim MC, Shin SM, Byun HS, Nam YY, Kim JM, Kim MK, Lee KY, Nam TC. The studies on treatment of liver disease using lasers and acupuncture in dogs. Kor J Vet Clin Med 1998; 15: 319-324
5 McGavin MD, Zachary JF. Pathologic basis of veterinary disease. In: Vascular disorders and thrombosis 4th ed. St. Louis: Mosby Co. 2006: 63-99
6 Olman MA, Gan RZ, Yen RT, Villespin I, Maxwell R, Pedersen C, Konopka R, Debes J, Moser KM. Effect of chronic thromboembolism on the pulmonary artery pressureflow relationship in dogs. J Appl Physiol 1994; 76: 875-881   DOI
7 Song KH, Kim DH, Hayasaki M. The PCR-based detection of Babesia gibsoni in dogs (German shepherds) reared in South Korea. Ann Trop Med Parasitol 2004; 98: 149-153   DOI   ScienceOn
8 Giger U. Hematology and immunology. In: Textbook of veterinary internal medicine, 5th ed. Pennsylvania: WB. Saunders Co. 1999: 1793-1797
9 Weinkle TK, Center SA, Randolph JF, Warner KL, Barr SC, Erb HN. Evaluation of prognostic factors, survival rates, and treatment protocols for immune-mediated hemolytic anemia in dogs: 151 cases (1993-2002). J Am Vet Med Assoc 2005; 226: 1874-1878
10 Choi EW, Lee CW Immune mediated hemolytic anemia. J Vet Clin 2001;18:288-292   과학기술학회마을
11 Thompson JP. Systemic immune-mediated disease. In: Small Animal Practice. Ohio: WE. Saunders Co. 1994: 171-174
12 Nelson RW, Couto CG. Small animal internal medicine. In: Hematology and immunology 3rd ed. St. Louis: Mosby Co. 2003: 1156-1169
13 McManus PM, Craig LE. Correlation between leukocytosis and necropsy findings in dogs with immune-mediated hemolytic anemia: 34 cases(I 994-1 999). J Am Vet Med Assoc 2001; 218: 1308-1313   DOI   ScienceOn
14 Bass MC, Schultze AE. Essential thrombocythemia in a dog: case report and literature review. J Am Anim Hosp Assoc 1998; 34:197-203   DOI
15 Ettinger SJ. Hematology and immunology. In: Veterinary internal medicine, 6th ed. St. Louis: Elsevier Co. 2004: 18781901
16 Weiss DJ, Brazzell JL. Detection of activated platelets in dogs with primary immune-mediated hemolytic anemia. J Vet Intern Med 2006; 20: 681-683
17 Schoen AM. Veterinary acupuncture: ancient art to modem medicine, 2nd ed. St. Louis; Mosby Co. 2001; 158-274
18 Tilley LP. The 5-minute veterinary consult, 2nd ed. London: British library. 1997: 434-435