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Ultrasonographic Resistive Index of the Interlobar Renal Artery in Renal Failure Induced by Ochratoxin A and Citrinin Toxicosis in Dogs  

Bae, Jun-Woo (College of Veterinary Medicine, Kyungpook National University)
Seong, Yun-Sang (College of Veterinary Medicine, Kyungpook National University)
Oh, Tae-Ho (College of Veterinary Medicine, Kyungpook National University)
Jang, Kwang-Ho (College of Veterinary Medicine, Kyungpook National University)
Lee, Keun-Woo (College of Veterinary Medicine, Kyungpook National University)
Eom, Ki-Dong (College of Veterinary Medicine, Konkuk University)
Publication Information
Journal of Veterinary Clinics / v.23, no.4, 2006 , pp. 427-431 More about this Journal
Abstract
Pulse Doppler ultrasonographic evaluation was performed to investigate the resistive index (RI) of the Interlobar renal artery in 17 dogs (32 kidneys) which were diagnosed with an acute renal failure caused by ochratoxin-A and citrinin contaminated commercial diet. RI was investigated in 7 normal beagle dogs and recovered patients. The mean of RI was resulted as $0.69{\pm}0.04$ in normal dog, however, significantly (p<0.001) increased as $0.76{\pm}0.05$ in renal failure dog. But RI had no relationship with the results of blood chemistry, urine analysis, and excretory urographic image quality. From these results, even though the results of the renal function test were within a normal reference range, it was considered that RI index is more reliable to represent a damaged renal parenchyma, and may have the potential to be a useful clinical tool in monitoring of the renal function.
Keywords
ultrasonography; resistive index; ochratoxin-A; citrinin; renal failure;
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1 Daley CA, Finn-Bodner ST, Lenz SD. Contrast induced renal failure documented by color-Doppler imaging in a dog. J Am Anim Hosp Assoc 1994; 30: 33-37
2 Castegnaro M, Chemozemsky IN, Hietanen E, Bartsch H. Are mycotoxins risk factors for endemic nephropathy and associated urothelial cancers? Arch Geschwulstforsch 1990; 60: 295-303
3 Choi J, Lee H, Chang D, Lee K, Eom K, Lee Y, Choi M, Yoon J. Effect of dopamine on excretory urographic image quality and the prevention of contrast-induced nephropathy in dogs. J Vet Med Sci 2001; 63: 383-388   DOI   ScienceOn
4 Feeney DA, Thrall DE, Barber DL, Culver DH, Lewis RE. Normal canine excretory urogram: effects of dose, time, and individual dog variation. Am J Vet Res 1979; 40: 1596-1604
5 Griffiths IB, Done SH. Citrinin as a possible cause of the pruritis, pyrexia and haemorrhagic syndrome in cattle. Vet Rec 1991; 129: 113-117   DOI   ScienceOn
6 Nyland TG, Fisher PE, Doverspike M, Hornof WJ, Olander HJ. Diagnosis of urinary tract obstruction in dog using duplex Doppler ultrasonography. Vet Radiol Ultrasound 1993; 34: 348-352   DOI
7 Platt JF, Rubin JM, Ellis JH. Acute renal failure: possible role of duplex Doppler US in distinction between acute prerenal failure and acute tubular necrosis. Radiology 1991; 179: 419-423   DOI
8 Platt JF, Ellis JH, Rubin JM, DiPietro MA, Sedman AB. Intrarenal arterial Doppler sonography in patients with nonobstructive renal disease: correlation of resistive indices with biopsy findings. AJR 1990; 154: 1223-1227   DOI   ScienceOn
9 Paltt JF, Rubin JM, Bowerman RA, Marn CS. The inability to detect kidney disease on the basis of echogenicity. AJR 1988; 151: 317-319   DOI   ScienceOn
10 Saito M, Enomoto M, Tatsuno T, Uraguchi K. Yellowed rice toxins: luteoskyrin and related compounds, chlorine-containing compounds, citrinin and citreoviridin. In: Microbial toxins, 6th ed. New York: Academic Press. 1971: 299-380
11 Vrabcheva T, Petkova-Bocharova T, Grosso F, Nikolov I, Chernozemsky IN, Castegnaro M, Dragacci S. Analysis of ochratoxin A in foods consumed by inhabitants from an area with Balkan endemic nephropathy: a 1 month follow-up study. J Agric Food Chem 2004; 52: 2404-2410   DOI   ScienceOn
12 Walker R. Risk assessment of ochratoxin: current views of the European Scientific Committee on Food, the JECFA and the Codex Committee on Food Additives and Contaminants. Adv Exp Med Biol 2002; 504: 249-255
13 Biller DS, Bradley GA, Partingron BP. Renal medullary rim sign: ultrasonographic evidence of renal disease. Vet Radiol 1992; 33: 286-290   DOI
14 Nelson TR, Pretorius DB. The Doppler signal: where does it come from and what does it mean? AJR 1988; 151: 439-447   DOI   ScienceOn
15 Petersen LJ, Petersen JR, Ladefoged SD, Mehlsen J, Jensen HA. The pulsatility index and renal arteries in patients with hypertension and chronic renal failure. Nephrol Dial Transplant 1995; 10: 2060-2064
16 Krogh P. Role of ochratoxin in disease causation. Food Chem Toxicol 1992; 30: 213-224   DOI   ScienceOn
17 Morrow KL, Salmon MD, Lappin MR. Comparison of the resistive index to clinical parameters in dogs with renal disease. Vet Radiol Ultrasound 1996; 37: 193-199   DOI   ScienceOn
18 Platt JF. Duplex Doppler evaluation of native kidney dysfunction: obstructive and nonobstructive disease. AJR 1992; 158: 1035-1042   DOI   ScienceOn
19 Jimenez M, Mateo R, Querol A. Huerta T, Hernandez E. Mycotoxins and mycotoxigenic moulds in nuts and sunflower seeds for human consumption. Mycopathologia 1991; 115: 121-127   DOI
20 Wolf G Ochratoxin A: contamination of Foods and Consumer Exposures. Arch Lebensmittelhygiene 2000; 51: 81-128
21 Krogh P, Hasselager E, Friis P. Studies on fungal nephrotoxicity. 2. Isolation of two nephrotoxic compounds from Penicillium viridicatum Westling: citrinin and oxalic acid. Acta Pathol Microbiol Scand [B] 1970; 78: 401-413
22 Mastorikou I, Robbins ME, Bywaters T. Resistance and pulsatility Doppler indices: how accurately do they reflect changes in renal vascular resistance. Br J Radiol 1993; 66: 577-580   DOI   ScienceOn
23 Pollard R, Nyland TG, Bernsteen L, Gregory CR, Hornof WJ. Ultrasonographic evaluation of renal autografts in normal cats. Vet Radiol Ultrasound 1999; 40: 380-385   DOI
24 Dodd GD, Kaufman PN, Bracken RB. Renal arterial duplex Doppler ultrasound in dogs with urinary obstruction. J Urol 1991; 145: 644-646   DOI
25 Townsend RR, Tomlanovich SJ, Goldstein RB, Filly RA. Combined Doppler and morphologic sonographic evaluation of renal transplant rejection. J Ultrasound Med 1990; 9: 199-206
26 Brkljacic B, Drinkovic I, Sabljar-Matovinovic M, Soldo D, Morovic-Vergles J, Vidjak V, Hebrang A. Intrarenal duplex Doppler sonographic evaluation of unilateral native kidney obstruction. J Ultrasound Med 1994; 13: 197-204
27 Hanika C, Carlton WW, Tuite J. Citrinin mycotoxicosis in the rabbit. Food Chem Toxicol 1983; 21: 487-493   DOI   ScienceOn