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Epidemiological Observation on Recent Outbreaks of Canine Distemper in Korea  

Doo, Kim (Department of Veterinary Medicine, Kangwon National University)
Ji-young, Park (Department of Veterinary Medicine, Kangwon National University)
So-jeo, Ahn (Department of Veterinary Medicine, Kangwon National University)
Seok-young, Jeoung (Department of Veterinary Medicine, Kangwon National University)
Son-il, Pak (Department of Veterinary Medicine, Kangwon National University)
Publication Information
Journal of Veterinary Clinics / v.21, no.3, 2004 , pp. 229-235 More about this Journal
Abstract
To characterize the recent outbreaks of canine distemper (CD) in Korea, we carried out epidemiological investigations by clinical observations, serum neutralizing (SN) antibody titer determination and RT-PCR on the 315 dogs which were clinically suspected as canine distemper virus (CDV) infection. One hundred and sixty two of 315 dogs were infected with CDV. Breed or gender did not seem to have effects on the prevalence of CD. The major part of dogs were in young age from 6 weeks to 18 weeks of age, and were not vaccinated or incompletely vaccinated. Clinical signs of dogs with CD were multi systemic and extremely variable. Dogs died from CD had significantly more ocular signs and neurologic signs than those of dogs survived (p<0.05). The SN titers against CDV of 157 (96.9%) dogs were under 1:16, which is less than protective level. One possible explanation for recent outbreaks of CD in Korea might be low antibody titers against CDV because of vaccination failure. Therefore, to reduce the impact of virulent infection in the dog population, dogs should be vaccinated adequately and prophylactic measures should include isolation of young dogs from the dog population until vaccination can be expected to provide protection.
Keywords
Canine distemper; epidemiology; Korea;
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