Browse > Article

Changes of Xenograft According to Extracted Time with Chloroform-methanol Solution in freeze-dried Cortical bone of Pig Transplanted to Dogs  

최인혁 (전북대학교 수의과대학)
이미진 (전북대학교 수의과대학)
최은경 (충북대학교 수의과대학)
정인성 (건국대학교 수의과대학)
최성진 (전북대학교 수의과대학)
김남수 (전북대학교 수의과대학)
Publication Information
Journal of Veterinary Clinics / v.20, no.1, 2003 , pp. 91-95 More about this Journal
Abstract
It has been known that periods of absorption varies allografts or xenografts of transplantations of freeze-dried cortical bone(FDCB). In this study changes of absorption of FDCB in xenograft transplantations were evaluated according to extracted time with chloroform-methanol solution(CM sol.). The FDCB from pig was removed soft tissue by surgical knife. Fat of the FDCB was removed with treatments of CM sol. for 2, 6, and 10 days, then the treated FDCB was freeze-dried at $-80^{\circ}C$ and sterilized with ethylene oxide gas. The FDCB was transplanted to fifteen millimeter artificial-defected regions of 6 dogs on fibular diaphyses. This was biweekly examined by radiograph for 18 weeks. In result new bone formation with FDCB treated for 6 days was higher than the other bones treated for 2 and 10 days. Duration of absorption with FDCB treated for 6 days was longer than the others. The remain with FDCB treated for 10 days was more than the others.
Keywords
Chloroform-methanol solution; Freeze dried bone; Bone resorption; Xenograft; Pig;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 동결건조골에 대한 소고 /
[ 장익열 ] / J Kor Orthop Assoc
2 Lipid extracted bank bone: bone conductive and mechanical properties /
[ Thoren K;Aspenberg P;Thorngren KG ] / Clin Orthop Rel Res
3 Bone morphogenetic proteins: from basic science to clinical applications /
[ Reddi AH ] / J Bone Joint Surg Am
4 Bone and cartilage transplantation /
[ Fanson PD;Markel MD ] / VCOT
5 Preparation of bank bone using defatting, freeze-drying and sterilization with ethylene oxide gas. Part 2. Clinical evaluation of its efficacy and safety /
[ Kakiuchi M;Ono K ] / In Orthop
6 The resorption of vital and devitalized bone in vitro: significance for bone graft /
[ Kingsmill VJ;Boyde A;Jones SJ ] / Calcif Tissue Int   DOI   ScienceOn
7 An antigenic anti-morphogenetic bone hydrophobic glycopeptide(AHG) /
[ Mikulski AJ;Urist MR ] / Prep Biochem   DOI
8 Bone repair induced by bone morphogenetic protein in ulnar defects in dogs /
[ Nilsson OS;Urist MR;Dawson EG(et al.) ] / J Bone Joint Surg [Br]   DOI
9 Bone formaiton by autoinduction /
[ Urist MR ] / Science   DOI
10 A Comparative study of anorganic xenogenic bone and autogenous bone implant for bone regeneration in rabbits /
[ Young C;Sandstedt P;Skohlund A ] / Int J Oral Maxillofac Implants
11 /
[ Weisbrode SE ] / Function, structure, and Healing of the musculoskeletal system. small animal orthopadics
12 Biology of bone transplantation /
[ Burchardt H ] / Orthop Clin Nor Am
13 同種保存骨その意義と新しい應用 /
[ 垣內 雅明 ] / 日整會誌
14 Bovine bone implant with bovine bone morphogenetic protein in healing a canine ulnar defect /
[ Tuominen T;J ms T;Tuukkanen J(et al.) ] / In Orthop
15 Treatment of acute and chronic bone infection /
[ Brinker WO;Piermattei DL;Flo GL ] / Handbook of small animal orthopedics & fracture treatment(2nd ed.)
16 The fate of freeze-dried bone allograft /
[ Burwell RG ] / Transplan proc
17 The effects of freeze-drying and rehydration on cancellous bone /
[ Conrad EU;Ericksen DP;Tencer AF(et al.) ] / Clin Orthop Related Res
18 Immune responses to osteochondral allografts: nature and significance /
[ Friedlaender GE;Horowitz MC ] / Orthopedics
19 Bone grafts /
[ Martinez SA;Walker T ] / Vet Clin Nor Am   DOI
20 Repair of experimental autologous grafts of cortical bone /
[ Burchardt H;Busbee Ⅲ GA;Enneking WF ] / J Bone Joint Surg
21 Bone transplantation /
[ Urist MR ] / Fundamental and Clinical Bone Physiology
22 Freeze-dried allogeneic segmental cortical-bone grafts in dogs /
[ Burchardt H;Jones H;Glowczewskie FP(et al.) ] / J Bone Joint Sur   DOI
23 Xenogeneic moose(Alces alces) bone morphogenetic protein (mBMP)-induced repair of critical-size skull defects in sheep /
[ Viljanen VV;Gao TJ;Lindholm TC(et al.) ] / Int J Oral Maxillofac Sur   DOI   ScienceOn
24 Bone grafting /
[ Stevenson S ] / Textbook of small animal surgery
25 Transplantation of bone /
[ Burchardt H;Enneking WF ] / Surg Clin North Am   DOI
26 Studies on the Antigenicity of bone. Ⅰ. Freeze-dried and deep-frozen bone allografts in rabbits /
[ Friedlaender GE;Strong DM;Sell KW ] / J Bone Joint Surg   DOI
27 Defatted gas-sterilised cortical bone allograft for posterior lumbar interbody vertebral fusion /
[ Kakiuchi M;Ono K ] / Int Orthop   DOI   ScienceOn
28 동결건조한 산양뼈의 개이식 효과 /
[ 최인혁;이종일 ] / Korean J Vet Clin Med   과학기술학회마을
29 Repair and Grafting of Bone /
[ Cutting CB;McCarthy JG;Knize DM ] / Plastic Surgery
30 Bone transplantation /
[ Hubble MJW ] / Current Orthopaedics   DOI   ScienceOn
31 Lipid extraction decreases the specific immunologic response to bone allografts in rabbits /
[ Thoren K;Aspenberg P;Thorngren KG ] / Acta Orthop Scand   DOI
32 Biology of vascularized bone grafts /
[ Goldberg VM;Shaffer JW;Field G(et al.) ] / Orthop Clin Nor Am
33 A chemosterilized antigen-extracted autodigested alloimplant for bone banks /
[ Urist MR;Mikulski A;Boyd SD ] / Arch Surg   DOI   ScienceOn
34 Biologic principles of bone induction: application to bone grafts /
[ Habal MB;Reddi AH ] / Bone grafts and bone substitutes
35 Modulation of osteoclast differentiation by local factors /
[ Suda T;Udagawa N;Nakamura I;Miyaura C;Takahashi N ] / Bone   DOI
36 개의 비유합 골절 모델에 있어서 동결 건조골이식의 효과 /
[ 최인혁;김현경;김남수 ] / Korean J Vet Res