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Changes of Xenograft According to Extracted Time with Chloroform-methanol Solution in freeze-dried Cortical bone of Pig Transplanted to Dogs  

최인혁 (전북대학교 수의과대학)
이미진 (전북대학교 수의과대학)
최은경 (충북대학교 수의과대학)
정인성 (건국대학교 수의과대학)
최성진 (전북대학교 수의과대학)
김남수 (전북대학교 수의과대학)
Publication Information
Journal of Veterinary Clinics / v.20, no.1, 2003 , pp. 91-95 More about this Journal
Abstract
It has been known that periods of absorption varies allografts or xenografts of transplantations of freeze-dried cortical bone(FDCB). In this study changes of absorption of FDCB in xenograft transplantations were evaluated according to extracted time with chloroform-methanol solution(CM sol.). The FDCB from pig was removed soft tissue by surgical knife. Fat of the FDCB was removed with treatments of CM sol. for 2, 6, and 10 days, then the treated FDCB was freeze-dried at $-80^{\circ}C$ and sterilized with ethylene oxide gas. The FDCB was transplanted to fifteen millimeter artificial-defected regions of 6 dogs on fibular diaphyses. This was biweekly examined by radiograph for 18 weeks. In result new bone formation with FDCB treated for 6 days was higher than the other bones treated for 2 and 10 days. Duration of absorption with FDCB treated for 6 days was longer than the others. The remain with FDCB treated for 10 days was more than the others.
Keywords
Chloroform-methanol solution; Freeze dried bone; Bone resorption; Xenograft; Pig;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
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