Browse > Article

Use of selegiline in 3 Cases of Canine Pituitary-dependent Hyperadrenocorticism  

김주민 (서울대학교 수의과대학)
황철용 (서울대학교 수의과대학)
윤정희 (서울대학교 수의과대학)
윤화영 (서울대학교 수의과대학)
한홍율 (서울대학교 수의과대학)
Publication Information
Journal of Veterinary Clinics / v.19, no.4, 2002 , pp. 455-460 More about this Journal
Abstract
Pituitary-dependent hyperadrenocorticism (PDH) was diagnosed with history taking, physical examination, complete blood count, serum chemistry profiles, abdominal radiology, ultrasonography and adrenal function tests in 3 dogs. Their clinical signs were polyuria, polydipsia, polyphagia, bilateral symmetrical truncal alopecia and secondary infection in skin or urinary tract. Especially one dog showed severe clinical signs such as calcinosis cutis and delayed wound healing. These 3 dogs were diagnosed as PDH, and treated with selegiline 1-2 mg/kg /ay sid PO. 2 dogs with clinical signs of PDH were disappeared and improved, but 1 dog with severe illness progressed gradually despite of selegiline and mitotane application, and eventually died.
Keywords
Pituitary-dependent hyperadrenocorticism(PDH); dogs; selegiline;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Hyperadrenocorticism /
[ Edward CF ] / Textbook of veterinary internal medicine
2 medical treatment of canine pituitary-dependent hyperadrenocorticism(Cushing's disease) /
[ Peterson ME. ] / Vet Clin North Am Small Anim Prac
3 Hyperadrenocorticism in the dog; canine Cushing's syndrome /
[ Owens JM;Drucker WD. ] / Vet Clin North Am Small Anim Prac
4 Complications and concurrent disease associated with canine hyperadrenocorticism /
[ Nichols R ] / Vet clin North Am Small Anim Prac
5 Screening tests used inthe diagnosis of canine hyperadrenocorticism /
[ Mack RE ] / Semin Vet Med Surg (Small Anim)
6 Ultrasonography of the adrenal glnad in dogs /
[ Kaser-Horz B;Sanders HM ] / Schweiz Arch Tierheikd
7 Diagnosis of hyperadrenocorticism in dogs as compared to human diagnostic methods; a review /
[ Thuroczy J;Balogh L;Huszenicza G;Janoki GA;Kulcsar M. ] / Acta Vet Hung
8 Retrospective evaluation of urinary tract infection in 42 dogs with hyperadrenocorticism or diabetes mellitus or both /
[ Forrester SD;Troy GC;Dalton MN;Huffman JW;Holtzman G ] / J Vet Intern Med
9 Hypophysectomy as a treatment for canine and feline Cushing's disease /
[ Meij BP. ] / Vet Clin North Am Small Prac
10 Canine hyperadrenocorticism /
[ Michael EH ] / BSAVA manual of small animal endocrinology(2nd ed.)
11 Problems associated with medical therapy canine hyperadrenocorticism /
[ Nichols R. ] / Probl Vet med
12 Concurrent illness and complications associated with canine hyperadrenocorticism /
[ Nichols R. ] / Semin Vet MEd Surg (Small Anim)
13 Hyperadrenocorticism in dogs /
[ Richard WN. ] / Small animal internal medicine
14 Canine pituitary dependent hyperadrenocorticism; a spontaneous animal model for neurodegenerative disorders and their treatment with Ldeprenyl /
[ Bruyette DS;Ruehl WW;Smidberg TL ] / Prog Brain Res
15 Concurrent pituitary and adreal tumors in dogs with hyperadrenocorticism; 17 cases (1978-1995) /
[ Greco DS;Peterson ME;Davidson AP;Feldman EC;Komurek K. ] / J Am Vet Med Assoc
16 Comparative aspects of Cushing's syndrome in dogs and cats /
[ Feldman EC;Nelson RW ] / Endocrinol Metab clin North Am
17 L-Deprenyl in the treatment of canine pituitary-dependent hyperadrenocorticism /
[ David SB;William WR ] / Current Veterinary Therapy ⅩⅢ
18 Ultrasonography of the adrenal glnad /
[ Schelling CG ] / Probl Vet Med
19 Use of ACTH stimulation tests to monitor the treatment of canine hyperadrenocorticism /
[ Dunn KJ;Herrtage ME;Dunn JK ] / Vet Rec
20 Laboratory parameters for thetrol of the course of therapy of canine Cushing's syndrome /
[ Reush C;Hahnle B. ] / Tierarztl Prax
21 Use of endogenous ACTH concentration and adrenal ultrasonography to distinguish the cause of canine hyperadrenocorticism /
[ Gould SM;Bainse EA;Mannion PA;Evans H;Herrtage ME ] / J Small Anim Prac   ScienceOn
22 An alternative protocol for the medical management of canine pituitary-dependent hyperadrenocorticism /
[ Rijnberk A;Belshaw BE ] / vet Rec   ScienceOn
23 Ultrasonographic characteristics of both adrenal glands in 15 dogs with functional adrenocortical tumors /
[ Hoerauf A;Reusch C. ] / J Am Anim Hosp Assoc
24 Canine cognitive dysfunction as a model for hyman age-related cognitive decline, dementia and Alzheimet's disease; clinical presentation, cognitive testing, pathology and response to L-deprenyl /
[ Ruehl WW;Rruyette DS;DePaoli A;Cotman CW;Head E;Milgram NW;Commings BJ ] / Prog brain Res
25 hyperadrenocorticism and hypothyroidism in a dog /
[ Hess RS;Ward CR. ] / J Am Anim Hosp Assoc
26 o,p'-DDD(mitotane) treatment of canine pituitary-dependent hyperadrenocorticism /
[ Peterson ME. ] / J Am Vet Med Assoc
27 Management of canine pituitary-dependent hyperadrenocorticism with L-depreny(Anipryl) /
[ Bruyette DS;Ruehl WW;Entriken T;Griffin D;Darling L ] / Vet Clin North Am Small Anim Pract
28 The efficacy of L-deprenyl in dogs with pituitary-dependent hyperadrenocoriticism /
[ Reusch CE;Steffen T;Hoerauf A. ] / J Vet Intern Med