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http://dx.doi.org/10.24304/kjcp.2022.32.4.321

Pilot Prospective Study for Validation of Korean Medication Review Tool for Nursing Home Residents in Older Adults Living in Long-term Care Facilities  

Hyun-Woo Chae (College of Pharmacy, Seoul National University)
Jonghyun Jeong (College of Pharmacy, Seoul National University)
Kwanghee Jun (College of Pharmacy, Seoul National University)
Ju-Yeun Lee (College of Pharmacy, Seoul National University)
Publication Information
Korean Journal of Clinical Pharmacy / v.32, no.4, 2022 , pp. 321-327 More about this Journal
Abstract
Background: To implement medication management service in Korean nursing home (NH), medication review tool for residents in Korean long-term care facilities was developed. This prospective pilot study aimed to verify the applicability of this newly developed tool and to evaluate the drug related problems (DRPs) identified by pharmacists' medication review in NH setting. Methods: This study was carried out in two NHs in Korea. The elderly residents (65 or older) using 5 or more medications were eligible. Pharmacists conducted medication review and identified the DRPs and potentially inappropriate medications (PIMs) based on the newly developed tool. Results: Among 43 NH residents, 27 residents agreed to participate. The median age was 87 and about 55.6% of them were taking 10 or more medications. Pharmacists identified a total of 37 PIMs in 18 NH residents (66.7%) and 54 DRPs in 22 residents (81.5%). The most frequent PIM was general-PIM (26 cases) followed by PIM under specific diseases or conditions (7 cases). Out of 77 items contained in the tool, 15 items were detected in study participants. 'Continued use or regular daily use of hypnotics' was the most highly detected item (9 cases) followed by 'multiple prescriptions within each class of hypnotics/sedatives' (5 cases). Among 54 DRPs identified, pharmacist intervened 39 cases (72.2%) and interventions were accepted in 18 cases (46.1%). Conclusion: This pilot study demonstrated that newly developed tool is feasible for the nursing home residents. However, further studies with larger population are warranted.
Keywords
long-term care facility; medication review; medication review tool; potentially inappropriate medications;
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1 Statistics Korea. 2022 statistics on the aged Available from http://kostat.go.kr/portal/eng/pressReleases/11/3/index.board. Accessed November 26, 2022.
2 Kang SH, Kim HR. Status of long-term care service and direction to enhance the role of insurance companies. Available from https://www.kiri.or.kr/report/downloadFile.do?docId=5140. Accessed November 26, 2022.
3 Ruangritchankul S, Peel NM, Hanjani LS, Gray LC. Drug related problems in older adults living with dementia. PLoS One 2020;15(7):e0236830.   DOI
4 Hwang HJ, Kim SH, Lee KS. Potentially inappropriate medications in the elderly in Korean long-term care facilities. Drugs Real World Outcomes 2015;2(4):355-61.   DOI
5 Ontario Ministry of Health and Long-Term Care. Medscheck Available from https://www.health.gov.on.ca/en/pro/programs/drugs/medscheck/medscheck_original.aspx. Accessed Nov 26 2022.
6 Moon A, Cho H, Jang S, Kang E, Jang S. Pharmacy-led medication management services in long-term care facilities: Lessons from other countries for Korea. Yakhak Hoeji 2020;64(2):166-72.   DOI
7 Australian Government Department of Health. Program rules: Quality use of medicines. Available from https://www.ppaonline. com.au/programs/medication-management-programs/residential-medication-management-review-and-quality-use-of-medicines. Accessed November 26 2022.
8 Park J-Y, Jun K, Baek Y-S, Park S-Y, Lee J-Y. Medication use review tools for community dwelling older patients: A systematic review. Korean J Clin Pharm 2021;31(1):61-78.   DOI
9 By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel. American geriatrics society 2019 updated AGS Beers criteria® for potentially inappropriate medication use in older adults. J Am Geriatr Soc 2019;67(4):674-94.   DOI
10 O'Mahony D, O'Sullivan D, Byrne S, O'Connor MN, Ryan C, Gallagher P. STOPP/START criteria for potentially inappropriate prescribing in older people: Version 2. Age Ageing 2014;44(2):213-18.   DOI
11 Nyborg G, Straand J, Klovning A, Brekke M. The Norwegian General Practice--Nursing Home Criteria (NORGEP-NH) for potentially inappropriate medication use: A web-based delphi study. Scand J Prim Health Care 2015;33(2):134-41.   DOI
12 Khodyakov D, Ochoa A, Olivieri-Mui BL, et al. Screening tool of older person's prescriptions/screening tools to alert doctors to right treatment medication criteria modified for U.S. nursing home setting. J Am Geriatr Soc 2017;65(3):586-91.   DOI
13 Jun K, Lee S, Lee AY, Ah YM, Lee JY. Development of a medication review tool for residents in Korean long-term care facilities. Ther Adv Chronic Dis 2022;13:20406223221128444.
14 Wolrd Health Organization. Medication safety in polypharmacy: Technical report. Available from https://apps.who.int/iris/bitstream/ handle/10665/325454/WHO-UHC-SDS-2019.11-eng.pdf. Accessed November 26, 2022.
15 Pharmaceutical Care Network Europe Association. Classification for drug related problem v9. 1. Available from https://www.pcne. org/upload/files/417_PCNE_classification_V9-1_final.pdf. Accessed November 18, 2022.
16 Han JM, Heo K-N, Lee AY, et al. Developing national level high alert medication lists for acute care setting in Korea. Korean J Clin Pharm 2022;32(2):116-24.   DOI
17 Jokanovic N, Tan EC, Dooley MJ, Kirkpatrick CM, Bell JS. Prevalence and factors associated with polypharmacy in long-term care facilities: A systematic review. J Am Med Dir Assoc 2015;16(6):535.e1-12.
18 Fog AF, Mdala I, Engedal K, Straand J. Variation between nursing homes in drug use and in drug-related problems. BMC Geriatr 2020;20(1):336.   DOI
19 Bories M, Bouzille G, Cuggia M, Le Corre P. Drug-drug interactions in elderly patients with potentially inappropriate medications in primary care, nursing home and hospital settings: A systematic review and a preliminary study. Pharmaceutics 2021; 13(2):266.   DOI
20 Lexow M, Wernecke K, Sultzer R, Bertsche T, Schiek S. Determine the impact of a structured pharmacist-led medication review-a controlled intervention study to optimise medication safety for residents in long-term care facilities. BMC Geriatr 2022;22(1):307.   DOI
21 Halvorsen KH, Kucukcelik S, Garcia BH, Svendsen K. Assessing potentially inappropriate medications in nursing home residents by NORGEP-NH criteria. Pharmacy (Basel) 2019;7(1):26.   DOI