Browse > Article

MR Imaging Features of Acute Enterovirus 71 Encephalitis in a Patient with Hand-Foot-Mouth Disease: A Case Report  

Park, Byung-Sa (Department of Radiology, Eulji University Hospital)
Yu, In-Kyu (Department of Radiology, Eulji University Hospital)
Lee, Byung-Hee (Department of Radiology, Eulji University Hospital)
Publication Information
Journal of the Korean Society of Radiology / v.64, no.2, 2011 , pp. 113-116 More about this Journal
Abstract
We report here on the MR findings of the first Korean case of hand-foot-mouth disease(HFMD) complicated by acute enterovirus 71 (EV 71) encephalitis in a 33-month old girl. Conventional MR images of the patient showed the increased signal intensity(SI) on a T2-weighted image (WI) at the posterior aspect of the medulla, the pontine tegmen, the bilateral dentate nuclei of the cerebellum and the midbrain. There was no evidence of abnormal SI or contrast enhancement at the same areas of the brain on the pre- and post-contrast T1-WI. The diffusion weighted images (DWI) also revealed the bilateral symmetrical strong high SI at the posterior aspect of the medulla and pontine tegmen and there was low SI at the same areas on the apparent diffusion coefficient(ADC) map. DWI in addition to the conventional MR imaging may be helpful for the early detection of acute EV 71 encephalitis in a patient with HFMD.
Keywords
Hand, Foot and Mouth Disease; Magnetic Resonance Imaging; Brain Stem; Encephalitis, Enterovirus, Infection;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Kitamura A, Narisawa T, Hayashi A, Ashihara Y, Ishiko H, Minohara Y, et al. Serotype determination of enteroviruses that cause hand-foot-mouth disease: identification of enterovirus 71 and Coxsackievirus A16 from clinical specimens by using specific probe. Kansenshogaku Zasshi 1997;71:715-723   DOI
2 Wright PW, Strauss GH, Langford MP. Acute hemorrhagic conjunctivitis. Am Fam Physician 1992;45:173-178
3 Katiyar BC, Misra S, Singh RB, Singh AK, Gupta S, Gulati AK, et al. Adult polio-like syndrome following enterovirus 70 conjunctivitis (natural history of the disease). Acta Neurol Scand 1983;67:263-274   DOI   ScienceOn
4 Yin-Murphy M, Baharuddin-Ishak, Phoon MC, Chow VT. A recent epidemic of Coxsackie virus type A24 acute haemorrhagic conjunctivitis in Singapore. Br J Ophthalmol 1986;70:869-873   DOI   ScienceOn
5 Frieden IJ, Penneys NS. Viral infections. In: Schachner LA, Hansen RC. Pediatric Dermatology. New York: Churchill Living Stone;1988:1371-1413
6 Melnick JL. Enterovirus type 71 infections: a varied clinical pattern sometimes mimicking paralytic poliomyelitis. Rev Infect Disease 1984;6 Suppl 2:S387-S390   DOI
7 Nagy G, Takatsy S, Kukan E, Mihaly I, Domok I. Virological diagnosis of enterovirus type 71 infections: experiences gained during an epidemic of acute CNS diseases in Hungary in 1978. Arch Virol 1982;71:17-27
8 Shen WC, Chiu HH, Chow KC, Tsai CH. MR imaging findings of enteroviral encephalomyelitis: an outbreak in Taiwan. AJNR Am J Neuroradiol 1999;20:1889-1895
9 Sener RN. Herpes simplex encephalitis: diffusion MR imaging findings. Comput Med Imaging Graph 2001;25:391-397   DOI   ScienceOn