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Islet Cell Tumors of the Pancreas: A Variety of Multiphase Dynamic Imaging Findings with Pathologic Correlations Focusing on Nonfunctioning Tumors and Insulinomas  

Hong, Yoo-Jin (Department of Diagnostic Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine)
Yu, Jeong-Sik (Department of Diagnostic Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine)
Park, Chan-Il (Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine)
Kwon, Ji-Eun (Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine)
Chung, Jae-Joon (Department of Diagnostic Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine)
Kim, Joo-Hee (Department of Diagnostic Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine)
Kim, Ki-Whang (Department of Diagnostic Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine)
Publication Information
Journal of the Korean Society of Radiology / v.63, no.5, 2010 , pp. 463-469 More about this Journal
Abstract
Islet cell tumors (ICTs) are rare pancreatic neoplasms of neuroendocrine origin, posing a diagnostic challenge to radiologists. We illustrated a spectrum of features of pancreatic ICTs that could be found on multiphase dynamic CT or MRI, and elucidated the histopathologic characteristics by determining the contrast enhancement pattern of the lesions. Various enhancement patterns were dependant on the internal composition of the tumor, that is, the proportion of vascular densities for early enhancement and non-hypervascular interstitial tissue for late enhancement regardless of the size or functional behavior. This knowledge of the imaging-pathologic spectrum of ICTs could be helpful for the proper differential diagnosis from other pancreatic tumors.
Keywords
Pancreatic Neoplasms; Tomography, X-ray Computed; Islet Cell Tumor;
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