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Comparison of Diffusion Weighted Imaging and Contrast Enhanced Imaging on MRI for Breast Lesions  

Choi, Jae-Jeong (Department of Radiology, The Catholic University of Korea)
Kang, Bong-Joo (Department of Radiology, The Catholic University of Korea)
Cha, Eun-Suk (Department of Radiology, The Catholic University of Korea)
Kim, Sung-Hun (Department of Radiology, The Catholic University of Korea)
Lee, Ji-Hye (Department of Radiology, The Catholic University of Korea)
Jeh, Su-Kyung (Department of Radiology, The Catholic University of Korea)
Park, Michael Yong (Department of Radiology, The Catholic University of Korea)
Jeong, Seung-Hee (Department of Preventive Medicine, The Catholic University of Korea)
Yim, Hyeon-Woo (Department of Preventive Medicine, The Catholic University of Korea)
Publication Information
Journal of the Korean Society of Radiology / v.62, no.6, 2010 , pp. 585-591 More about this Journal
Abstract
Purpose: To retrospectively compare the MRI findings of diffusion-weighted imaging (DWI) and contrast-enhanced imaging (CEI) of breast lesions. Materials and Methods: From June 2005 to June 2007, 159 patients with 159 biopsy-proven breast lesions underwent breast MRIs including DWI and CEI. Two breast imaging radiologists reviewed the MRI findings by consensus for the presence of a high signal intensity on DWI and enhancement on CEI. The MRI findings and concordance of DWI and CEI findings were correlated with the pathologic diagnosis. Results: Of the 159 lesions 141 were malignant and 18 were benign. The sensitivity and specificity of DWI for detecting breast cancer was 96.5% (135/141) and 21.4% (5/18), respectively, compared to CEI, whose detection rate was 99.3% (140/141) and 33.3% (6/18), respectively. Larger lesions (> 1 cm) were more frequently detected by DWI. Of the enhanced malignancy, 96.4% (135/140) showed high signal intensity on DWI. The concordance of DWI and CEI findings in malignant lesions was significantly higher than benign lesions (95.7% vs. 61.1%, p<0.0001). Conclusion: High signal intensity on diffuse-weighted MRI shows a high degree of sensitivity for detecting breast cancer.
Keywords
Diffusion; Breast Neoplasm; Magnetic Resonance Imaging;
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