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http://dx.doi.org/10.15324/kjcls.2022.54.3.217

Development of Dairy Products Using Ficus carica Vinegar and the Effects on the Caco-2 Cell Line  

Heo, Ji Hye (Department of Biomedical Laboratory Science, Donggang University)
Publication Information
Korean Journal of Clinical Laboratory Science / v.54, no.3, 2022 , pp. 217-223 More about this Journal
Abstract
Among various health functional foods, probiotics constitute the largest market. The interest in probiotics is increasing continuously according to the research results that gut health can control the immune function of the body, prevent diseases, and assist in treatment. In this study, dairy products and dressing sauces were developed using Ficus carica vinegar (FV), and their effects on colon cells were analyzed. When 5% FV was added to regular milk, the satisfaction with the resulting yogurt and ricotta cheese was high. The dairy product was Leuconostoc lactis, and the number of bacteria was more than 1.0×107~1.0×108 CFU/mL. The product satisfied the health food standards as probiotics. An examination of the cell viability of Caco-2 cells, which proliferate similarly to human intestinal epithelial cells, revealed an approximately 19% increase in the proliferation rate when treated with whey at 10%. An antioxidant activity of up to 58% was recorded when the cells were treated with whey at various concentrations. In addition, excellent adhesion was observed for L.latis isolated from whey. This study confirmed that dairy products made using traditionally fermented FV assist intestinal health effectively as the microbiome.
Keywords
Ficus carica vinegar; Intestinal health; Leuconostoc lactis; Microbiome; Probiotics;
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Times Cited By KSCI : 4  (Citation Analysis)
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1 Kang CH, Han SH, Kim YG, Jeong Y, Paek NS. Antibacterial activity and probiotic properties of lactic acid bacteria isolated from traditional fermented foods. KSBB J. 2017;32:199-205. http://doi.org/10.7841/ksbbj.2017.32.3.199   DOI
2 Chung BH, Seo HS, Kim HS, Woo SH, Cho YG. Antioxidant and anticancer effects of fermentation vinegars with Phellinus linteus, Inonotus obliquus, and Pleurotus ostreatus. Korean J Medicinal Crop Sci. 2010;18:113-117.
3 Galkiewicz JP, Kellogg CA. Cross-kingdom amplification using bacteria-specific primers: complications for studies of coral microbial ecology. Appl Environ Microbiol. 2008;74:7828-7831. http://doi.org/10.1128/AEM.01303-08   DOI
4 World Health Organization and Food and Agriculture Organization of the United Nations. Probiotics in food. Health and nutritional properties and guidelines for evaluation, Geneva and Rome: World Health Organization and Food and Agriculture Organization of the United Nations; 2006 [cited 2022 June 1] Available from: https://www.fao.org/3/a0512e/a0512e.pdf
5 Ministry of Food and Drug Safety. Announcement of standards and specifications of health functional food Notification 2008-12 [Internet]. Seoul: Ministry of Food and Drug Safety; 2008 [cited 2022 June 2]. Available from: https://www.mfds.go.kr/brd/m_824/view.do?seq=41221&srchFr=&srchTo=&srchWord=&srchTp=&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&page=55
6 Seo JG, Lee GS, Kim JE, Chung MJ. Development of probiotic products and challenges. KSBB J. 2010;25:303-310.
7 Yi MR, Kang CH, Bu HJ. Acetic acid fermentation properties and antioxidant activity of lemongrass vinegar. Korean J Food Preserv. 2017;24:680-687. https://doi.org/10.11002/kjfp.2017.24.5.680   DOI
8 Heo JH. Antibacterial effect of various fermentation products and identification of differentially expressed genes of E.coli. Korean J Clin Lab Sci. 2022;54:119-124. http://doi.org/10.15324/kjcls.2022.54.2.119   DOI
9 Aihara K, Kajimoto O, Hirata H, Takahashi R, Nakamura Y. Effect of powdered fermented milk with Lactobacillus helveticus on subjects with high-normal blood pressure or mild hypertension. J Am Coll Nutr. 2005:24;257-265. https://doi.org/10.1080/07315724.2005.10719473   DOI
10 Bang SI, Gwon GH, Cho EJ, Lee AY, Seo WT. Characteristics of fermented vinegar using mulberry and its antioxidant activity. Korean J Food Preserv. 2020;27:651-662. https://doi.org/10.11002/kjfp.2020.27.5.651   DOI
11 Park SY, Seong KS, Lim SD. Anti-obesity effect of yogurt fermented by Lactobacillus plantarum Q180 in diet-induced obese rats. Korean J Food Sci An. 2016;36:77-83. https://doi.org/10.5851/kosfa.2016.36.1.77   DOI
12 Puebla-Barragan S, Reid G. Probiotics in cosmetic and personal care products: trends and challenges. Molecules. 2021;26:1249. https://doi.org/10.3390/molecules26051249   DOI
13 Amara AA, Shibl A. Role of probiotics in health improvement, infection control and disease treatment and management. Saudi Pharm J. 2015;23:107-114. https://doi.org/10.1016/j.jsps.2013.07.001   DOI
14 Ogunrinola GA, Oyewale JO, Oshamika OO, Olasehinde GI. The human microbiome and its impacts on health. Int J Microbiol. 2020;2020:8045646. https://doi.org/10.1155/2020/8045646   DOI
15 Lim YS, Kim J, Kang H. Isolation and identification of lactic acid bacteria with probiotic activities from Kimchi and their fermentation properties in milk. J Milk Sci Biotechnol. 2019;37:115-128. http://doi.org/10.22424/jmsb.2019.37.2.115   DOI
16 Pasternak S, Khlebobpros R. Scientometric analysis of human microbiome project. J Sib Fed Univ-Humanit Soc Sci. 2017;10: 1076-1082. https://doi.org/10.17516/1997-1370-0116   DOI
17 De Santis D, Giacinti G, Chemello G, Frangipane MT. Improvement of the sensory characteristics of goat milk yogurt. J Food Sci. 2019;84:2289-2296. https://doi.org/10.1111/1750-3841.14692   DOI
18 Son MJ, Lee SP. Effects of various polysaccharides on the physicochemical properties of the dextran culture containing carrot juice residue obtained from submerged culture using Leuconostoc citreum S5. J Korean Soc Food Sci Nutr. 2009;38:352-358. https://doi.org/10.3746/jkfn.2009.38.3.352   DOI
19 Kim YM, Yeon MJ, Choi NS, Chang YH, Jung MY, Song JJ, et al. Purification and characterization of a novel glucansucrase from Leuconostoc lactis EG001. Microbiol Res. 2010;165:384-391. https://doi.org/10.1016/j.micres.2009.08.005   DOI
20 Park MH, Choi YJ, Kim M, Kang HJ, Kam MY, Jung KI. Antioxidant and anti-inflammatory effects of mulberry (Morus alba) juice prepared using slow-speed masticating household juicer. J Korean Soc Food Sci Nutr. 2020;49:444-453. http://doi.org/10.3746/jkfn.2020.49.5.444   DOI
21 Young VB, Schmidt TM. Antibiotic associated diarrhea accompanied by large-scale alterations in the composition of the fecal microbiota. J Clini Microbiol. 2004;42:1203-1206. https://doi.org/10.1128/JCM.42.3.1203-1206.2004   DOI
22 Oh, HS, Kang ST. Quality characteristics and antioxidant activity of yogurt added with acanthopanax powder. Korean J Food Sci Technol. 2015;47:765-771. http://doi.org/10.9721/KJFST.2015.47.6.765   DOI
23 Kassinen A, Krogius-Kurikka L, Makivuokko H, Rinttila T, Paulin, L, Corander J, et al. The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects. Gastroenterology. 2007;133:24-33. https://doi.org/10.1053/j.gastro.2007.04.005   DOI