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http://dx.doi.org/10.22537/jksct.2020.18.2.136

Initial Serum Ammonia as a Predictor of Mortality in Patients with Acute Glufosinate Ammonium Herbicide Poisoning  

Ko, Eun Na Lae (Department of Emergency Medicine, Gyeongsang National University School of Medicine)
Kim, Dong Hoon (Department of Emergency Medicine, Gyeongsang National University School of Medicine)
Lee, Soo Hoon (Department of Emergency Medicine, Gyeongsang National University School of Medicine)
Jeong, Jin Hee (Department of Emergency Medicine, Gyeongsang National University School of Medicine)
Lee, Sang Bong (Department of Emergency Medicine, Gyeongsang National University School of Medicine)
Sung, Aejin (Department of Emergency Medicine, Gyeongsang National University School of Medicine)
Suh, Ja Hyoen (Department of Emergency Medicine, Gyeongsang National University School of Medicine)
Kang, Changwoo (Department of Emergency Medicine, Gyeongsang National University School of Medicine)
Publication Information
Journal of The Korean Society of Clinical Toxicology / v.18, no.2, 2020 , pp. 136-140 More about this Journal
Abstract
Purpose: The association of the initial serum ammonia level with in-hospital mortality in patients with acute glufosinate-ammonium herbicide poisoning was studied. Methods: This retrospective cohort study was conducted between March 2012 and August 2019 in the emergency department after glufosinate-ammonium herbicide poisoning. Survivors and non-survivors were analyzed using a Mann-Whitney U test and Fisher's exact test. Multivariate logistic regression analysis was performed to determine the independent risk factors for mortality. Results: One hundred and six patients were enrolled; 11 died, yielding a mortality of 10.4%. The serum bicarbonate level was significantly lower in the non-survival group than the survival group. Age, serum ammonia, blood urea nitrogen, creatinine levels, SOFA score, and APACHE II score were significantly higher in the non-survival group than the survival group. Age, serum ammonia, and creatinine level were independent risk factors for mortality in multivariate logistic regression analysis. Conclusion: The initial serum ammonia level is associated with mortality in patients with acute glufosinate herbicide poisoning.
Keywords
Glufosinate ammonium; Herbicide; Poisoning; Mortality;
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Times Cited By KSCI : 8  (Citation Analysis)
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